FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Trpmlc05523
Open Close
General Information
Symbol
Dmel\Trpmlc05523
Species
D. melanogaster
Name
FlyBase ID
FBal0184751
Feature type
allele
Associated gene
Dmel\Trpml
Associated Insertion(s)
PBac{PB}Trpmlc05523
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
piggyBac activity
(Gene Disruption Project members and Exelixis, 2005)
Progenitor genotype
Associated Insertion(s)
PBac{PB}Trpmlc05523
Cytology
Description
Allele components
Component
Use(s)
Also carries
FRT
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      trpmlc05523/Df(3L)Exel6135 and trpmlc05523/trpml1 adult escapers have a 100% penetrant crumpled wing phenotype.

      trpmlc05523/Df(3L)Exel6135 adult escapers show normal baseline excitatory junctional current amplitudes at the neuromuscular junction at both pH 5.75 and under reduced Mg[2+] conditions.

      (Sandstrom, 2011)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      Trpml1/Trpmlc05523 is rescued by Trpml+tVa

      (Sandstrom, 2011)
      Comments

      The crumpled wing phenotype seen in trpmlc05523/trpml1 adult escapers is completely rescued by trpml+tVa.

      (Sandstrom, 2011)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      CG8743c05523
      Trpmlc05523
      trpmlc05523
      (Sandstrom, 2011)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)