FB2026_02 , released June 18, 2026
Allele: Dmel\qvrf01257
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General Information
Symbol
Dmel\qvrf01257
Species
D. melanogaster
Name
FlyBase ID
FBal0185841
Feature type
allele
Associated gene
Dmel\qvr
Associated Insertion(s)
PBac{WH}qvrf01257
Carried in Construct
Also Known As
sssP2
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
piggyBac activity
(Gene Disruption Project members and Exelixis, 2005)
Progenitor genotype
Associated Insertion(s)
PBac{WH}qvrf01257
Cytology
Description

Insertion in the 3' untranslated region.

(Koh et al., 2008)
Allele components
Component
Use(s)
Inserted element
PBac{WH}
Regulatory region(s)
UAS
Also carries
FRT
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      qvrEY04063/qvrf01257 adults show a reduced amount of daily sleep compared to controls.

      (Wu et al., 2014)

      Homozygous females have a similar amount of daily sleep compared to wild-type flies, whereas homozygous males have slightly lower amounts of sleep than controls.

      qvrEY04063/qvrf01257 flies have a 30% reduction in daily sleep relative to control qvrEY04063/+ flies.

      Mechanical stimulation results in moderate reduction in the amount of sleep lost in qvrEY04063/qvrf01257 flies compared to controls. These flies show little or no rebound after the sleep deprivation.

      Mechanical stimulation results in an equivalent loss of sleep in homozygous flies and controls. The homozygous flies show a lack of rebound sleep after the sleep deprivation.

      Almost all qvrEY04063/qvrf01257 flies are rhythmic for circadian locomotor activity.

      Homozygous flies show ether-induced leg shaking.

      (Koh et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      CG33472f01257
      qvrf01257
      (Ruan et al., 2017)
      qvrf0
      (Ruan et al., 2017)
      sssP2
      (Wu et al., 2014, Koh et al., 2008)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)