FB2026_03 , released September 17, 2026
Allele: Dmel\C153
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General Information
Symbol
Dmel\C153
Species
D. melanogaster
Name
FlyBase ID
FBal0187947
Feature type
allele
Associated gene
Dmel\C15
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Campbell, 2005)
Progenitor genotype
Cytology
Description

Mutation results in a protein that is truncated before the homeodomain.

(Campbell, 2005)

Amino acid replacement: ?137term.

(Campbell, 2005)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3R:21,502,588..21,502,588 [+]
Nucleotide change:

C21502588T

Amino acid change:

Q170term | C15-PA

Reported amino acid change:

?137term

Comment:

Resulting protein is truncated before the homeodomain. Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Campbell, 2005)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      C153 mutants die soon after emerging. In C153 mutants, the aristae are shortened to a vestige. Additionally, the claws, pulvilli and empodium at the tip of the legs are missing and tarsal segments IV and V are reduced compared to wild type.

      (Campbell, 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Selected as: a mutation that enhances the reduced aristae phenotype in al130/alush mutants.

      (Campbell, 2005)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      C153
      Name Synonyms
      Secondary FlyBase IDs
        References (1)