FlyBase Gene Report: Dmel\C15

FB2026_02 , released June 18, 2026

FB2026_02 , released June 18, 2026

Gene: Dmel\C15

General Information

Symbol

Dmel\C15

Species

D. melanogaster

Name

C15

Annotation Symbol

CG7937

Feature Type

protein_coding_gene

FlyBase ID

FBgn0004863

Gene Model Status

Stock Availability

22 publicly available

Gene Summary

C15 (C15) encodes a transcription factor that regulates gene expression in the leg distal region. [Date last reviewed: 2019-07-11] (FlyBase Gene Snapshot)

All Summaries

Gene Snapshot
Alliance
Auto summary
Gene Group
Interactive Fly

Also Known As

cll, clawless

Key Links

Genomic Location

Cytogenetic map

Sequence location

3R:21,499,986..21,512,814 [+]

Recombination map

3-72

RefSeq locus

NT_033777 REGION:21499986..21512814

Sequence

Get Decorated FASTA

Genomic Maps

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (16 terms)

Molecular Function (4 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

contributes_to sequence-specific DNA binding

inferred from physical interaction with FLYBASE:al; FB:FBgn0000061

(Kojima et al., 2005)

Terms Based on Predictions or Assertions (3 terms)

CV Term

Evidence

References

enables DNA binding

inferred from electronic annotation with InterPro:IPR042247

(InterPro Project Members, 2004-)

inferred from electronic annotation with InterPro:IPR001356, InterPro:IPR020479, InterPro:IPR042247

(InterPro Project Members, 2004-)

enables DNA-binding transcription factor activity, RNA polymerase II-specific

inferred from electronic annotation with InterPro:IPR017970

(InterPro Project Members, 2004-)

inferred from biological aspect of ancestor with PANTHER:PTN001215631

(GO Reference Genome Project, 2011-)

enables DNA-binding transcription factor activity

inferred from electronic annotation with InterPro:IPR042247

(InterPro Project Members, 2004-)

Biological Process (10 terms)

Terms Based on Experimental Evidence (7 terms)

CV Term

Evidence

References

involved_in antennal morphogenesis

inferred from mutant phenotype

(Kojima et al., 2005)

involved_in chaeta development

inferred from mutant phenotype

(Kojima et al., 2005)

involved_in elongation of arista core

inferred from mutant phenotype

(Campbell, 2005)

involved_in imaginal disc-derived leg morphogenesis

inferred from mutant phenotype

(Kojima et al., 2005)

involved_in leg disc development

inferred from mutant phenotype

(Campbell, 2005)

involved_in negative regulation of DNA-templated transcription

inferred from mutant phenotype

(Kojima et al., 2005)

involved_in positive regulation of DNA-templated transcription

inferred from mutant phenotype

(Kojima et al., 2005)

Terms Based on Predictions or Assertions (3 terms)

CV Term

Evidence

References

involved_in animal organ development

inferred from biological aspect of ancestor with PANTHER:PTN001215631

(GO Reference Genome Project, 2011-)

involved_in regulation of DNA-templated transcription

inferred from electronic annotation with InterPro:IPR017970

(InterPro Project Members, 2004-)

involved_in regulation of transcription by RNA polymerase II

inferred from biological aspect of ancestor with PANTHER:PTN001215631

(GO Reference Genome Project, 2011-)

Cellular Component (2 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

part_of protein-containing complex

inferred from physical interaction with FLYBASE:al; FB:FBgn0000061

(Kojima et al., 2005)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

is_active_in nucleus

inferred from biological aspect of ancestor with PANTHER:PTN001215631

(GO Reference Genome Project, 2011-)

Gene Group (FlyBase)

NK-LIKE HOMEOBOX TRANSCRIPTION FACTORS

Protein Family (UniProt)

-

Protein Signatures (InterPro)

Summaries

Gene Snapshot

C15 (C15) encodes a transcription factor that regulates gene expression in the leg distal region. [Date last reviewed: 2019-07-11]

Gene Group (FlyBase)

NK-LIKE HOMEOBOX TRANSCRIPTION FACTORS -: NK-like (NKL) homeobox transcription factors are sequence-specific DNA binding proteins that regulate transcription. NKL transcription factors are homeobox genes closely related to Hox-like genes, a number of which are found in the NK cluster. Many of the NKL members contain an Engrailed Homology 1 (EH1) motif. (Adapted from FBrf0232555 and PMID:22094586).

Summary (Interactive Fly)

member of the 93E cluster of homeodomain proteins - regulates spatial patterning of the tarsus, a distal portion of the leg - homolog of vertebrate oncogene Hox11

Interactive Fly

Gene Model and Products

Number of Transcripts

1

Number of Unique Polypeptides

1

Please see the JBrowse view of Dmel\C15 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry Q7KS72)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

PDB - An information portal to biological macromolecular structures

3A01

Comments on Gene Model

Gene model reviewed during 5.47

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

FBtr0084111

1856

339

Additional Transcript Data and Comments

Reported size (kB)

2.3 (northern blot)

(Dear and Rabbitts, 1994)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

FBpp0083510

37.4

339

6.87

Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments

Reported size (kDa)

307 (aa); 34 (kD predicted)

(Dear and Rabbitts, 1994)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

PDB - An information portal to biological macromolecular structures

3A01

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\C15 using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

C15_1

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

0.54

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage

cardiogenic mesoderm

(Liu et al., 2008)

embryonic stage 4 -- 6

dorsal ectoderm anlage

Comment: anlage in statu nascendi

(Fisher et al., 2012)

embryonic stage 5

dorsal ectoderm anlage | restricted

(Stathopoulos et al., 2002)

embryonic stage 7 -- 8

amnioserosa anlage

(Fisher et al., 2012)

dorsal ectoderm

(Fisher et al., 2012)

embryonic stage 9 -- 10

amnioserosa primordium

(Fisher et al., 2012)

dorsal epidermis primordium

Comment: reported as dorsal epidermis anlage

(Fisher et al., 2012)

embryonic stage 11 -- 12

(Fisher et al., 2012)

dorsal epidermis primordium

(Fisher et al., 2012)

embryonic stage 13 -- 16

(Fisher et al., 2012)

embryonic brain

(Fisher et al., 2012)

embryonic dorsal epidermis

(Fisher et al., 2012)

larval ventral nerve cord

(Fisher et al., 2012)

northern blot

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 9 -- 17

Comment: reference states 4-24 hr AEL

(Dear and Rabbitts, 1994)

third instar larval stage

(Dear and Rabbitts, 1994)

pharate adult stage

(Dear and Rabbitts, 1994)

Additional Descriptive Data

C15 is highly expressed in cardiac mesoderm and is observed in cells posterior to the eve clusters

(Liu et al., 2008)

C15 is expressed in a restricted pattern in the dorsal region of the embryo corresponding to the presumptive dorsal ectoderm.

(Stathopoulos et al., 2002)

C15 transcripts are detected in embryos from 4 hours on with a peak in 12-24 hour embryos. They are also detected at lower levels in late larvae and early pupae.

(Dear and Rabbitts, 1994)

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

part_of protein-containing complex

inferred from physical interaction with FLYBASE:al; FB:FBgn0000061

(Kojima et al., 2005)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\C15 in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\C15

View exonic expression by tissue for Dmel\C15

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0004863

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

42544/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0004863

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0004863

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0004863

Flygut - An atlas of the Drosophila adult midgut

FBgn0004863

Images

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 6 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 14 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of C15

Transgenic constructs containing regulatory region of C15

Aberrations (Deficiencies and Duplications) ( 7 )

Inferred from experimentation ( 7 )

Gene partially disrupted in

(De Graeve et al., 2004)

Gene disrupted in

(Campbell, 2005)

(Campbell, 2005)

(Kojima et al., 2005)

(Kojima et al., 2005)

Gene not disrupted in

(Kojima et al., 2005)

(Kojima et al., 2005)

Inferred from location ( 3 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal | male limited, with Scer\GAL4^Bx-MS1096

C15^{UAS.ORF.GW.Tag:HA}

lethal | male limited | cold sensitive, with Scer\GAL4^Bx-MS1096

C15^{UAS.ORF.GW.Tag:HA}

partially lethal | recessive

C15^cll-dl92

C15¹

Other Phenotypes

Allele

abnormal neuroanatomy | adult stage, with Fili^GD2136, Scer\GAL4^Mz19-GAL4DBD

C15^p65AD

some die during immature adult stage | recessive

visible | female limited, with Scer\GAL4^Bx-MS1096

C15^{UAS.ORF.GW.Tag:HA}

visible | female limited | cold sensitive, with Scer\GAL4^Bx-MS1096

C15^{UAS.ORF.GW.Tag:HA}

Phenotype manifest in

Allele

adult olfactory receptor neuron Or47b, with Fili^GD2136, Scer\GAL4^Mz19-GAL4DBD

C15^p65AD

mesothoracic bristle

C15^cll-dl92

ocellar bristle

C15^cll-dl92

tarsal segment 4

wing | female limited, with Scer\GAL4^Bx-MS1096

C15^{UAS.ORF.GW.Tag:HA}

wing | female limited | cold sensitive, with Scer\GAL4^Bx-MS1096

C15^{UAS.ORF.GW.Tag:HA}

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (164)

11 of 14

Yes

Yes

10 of 14

No

Yes

10 of 14

No

Yes

2 of 14

No

No

2 of 14

No

No

2 of 14

No

No

2 of 14

No

No

2 of 14

No

No

2 of 14

No

No

2 of 14

No

No

2 of 14

No

No

2 of 14

No

No

2

2 of 14

No

No

2 of 14

No

No

2 of 14

No

Yes

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

Yes

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

5

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1

1 of 14

No

No

1

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

Yes

1 of 14

No

Yes

1 of 14

No

No

2

1 of 14

No

Yes

1 of 14

No

Yes

1 of 14

No

Yes

1 of 14

No

Yes

1 of 14

No

Yes

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

Yes

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1

1 of 14

No

No

1

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1

1 of 14

No

No

1

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1

1 of 14

No

No

1

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1

1 of 14

No

No

1 of 14

No

No

1

1 of 14

No

No

1 of 14

No

Yes

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

2

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1

1 of 14

No

No

1 of 14

No

Yes

1

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1

1 of 14

No

No

1

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1

1 of 14

No

No

1 of 14

No

No

1

1 of 14

No

No

1 of 14

No

No

1

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1

1 of 14

No

No

3

1 of 14

No

No

3

1 of 14

No

No

1

1 of 14

No

No

1 of 14

No

No

2

1 of 14

No

No

0

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

3

1 of 14

No

No

1

1 of 14

No

No

1

1 of 14

No

No

1

1 of 14

No

No

1

1 of 14

No

No

1

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1

1 of 14

No

No

1 of 14

No

Yes

1 of 14

No

No

1 of 14

No

No

1

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1

1 of 14

No

No

1

1 of 14

No

No

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (124)

10 of 14

Yes

Yes

10 of 14

Yes

Yes

9 of 14

No

Yes

2 of 14

No

No

2 of 14

No

No

2 of 14

No

No

2 of 14

No

No

2 of 14

No

No

2 of 14

No

No

2 of 14

No

No

2 of 14

No

No

2 of 14

No

No

2 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

Yes

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

Yes

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

Yes

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

Yes

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

Yes

1 of 14

No

No

Rnor\LOC100361016

1 of 14

No

Yes

Rnor\LOC100911668

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

Yes

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

Yes

1 of 14

No

Yes

1 of 14

No

Yes

1 of 14

No

No

1 of 14

No

Yes

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

Yes

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

Mus musculus (laboratory mouse) (162)

11 of 14

Yes

Yes

10 of 14

No

Yes

9 of 14

No

Yes

2 of 14

No

No

2 of 14

No

No

2 of 14

No

No

2 of 14

No

No

2 of 14

No

No

2 of 14

No

No

2 of 14

No

No

2 of 14

No

No

2 of 14

No

No

2 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

Yes

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

3

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

3

1 of 14

No

No

1 of 14

No

No

1

1 of 14

No

No

1 of 14

No

No

1 of 14

No

Yes

1 of 14

No

No

0

1 of 14

No

No

1 of 14

No

No

0

1 of 14

No

No

0

1 of 14

No

No

1 of 14

No

No

1

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1

1 of 14

No

Yes

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

0

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

5

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

Yes

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1

1 of 14

No

No

1 of 14

No

No

3

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

Yes

1 of 14

No

Yes

1 of 14

No

Yes

1 of 14

No

Yes

1 of 14

No

Yes

1 of 14

No

Yes

1 of 14

No

Yes

1 of 14

No

Yes

1 of 14

No

Yes

1 of 14

No

Yes

1 of 14

No

Yes

1 of 14

No

Yes

1 of 14

No

Yes

1 of 14

No

Yes

1 of 14

No

Yes

1 of 14

No

Yes

1 of 14

No

Yes

1 of 14

No

Yes

1 of 14

No

Yes

1 of 14

No

Yes

1 of 14

No

Yes

1 of 14

No

Yes

1 of 14

No

Yes

1 of 14

No

Yes

1 of 14

No

Yes

1 of 14

No

Yes

1 of 14

No

Yes

1 of 14

No

Yes

1 of 14

No

Yes

1 of 14

No

Yes

1 of 14

No

No

1 of 14

No

Yes

1 of 14

No

No

1 of 14

No

Yes

1 of 14

No

No

1 of 14

No

No

1

1 of 14

No

No

1 of 14

No

No

1

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

Xenopus tropicalis (Western clawed frog) (135)

6 of 13

Yes

Yes

6 of 13

Yes

Yes

5 of 13

No

Yes

Xtro\LOC100490929

2 of 13

No

No

Xtro\LOC101732809

2 of 13

No

No

2 of 13

No

Yes

1 of 13

No

No

1 of 13

No

Yes

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

Yes

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

Xtro\homeobox100496651-provisional

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

Yes

1 of 13

No

Yes

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

Yes

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

Xtro\LOC100485081

1 of 13

No

No

Xtro\LOC100485335

1 of 13

No

No

Xtro\LOC100485697

1 of 13

No

No

Xtro\LOC100486032

1 of 13

No

No

Xtro\LOC100487588

1 of 13

No

No

Xtro\LOC100492873

1 of 13

No

No

Xtro\LOC100493706

1 of 13

No

No

Xtro\LOC100496089

1 of 13

No

No

Xtro\LOC100497614

1 of 13

No

No

Xtro\LOC101731251

1 of 13

No

No

Xtro\LOC101731897

1 of 13

No

No

Xtro\LOC116406456

1 of 13

No

Yes

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

Yes

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

Danio rerio (Zebrafish) (166)

11 of 14

Yes

Yes

10 of 14

No

Yes

Drer\LOC100008066

9 of 14

No

Yes

9 of 14

No

Yes

2 of 14

No

No

2 of 14

No

No

2 of 14

No

No

2 of 14

No

No

2 of 14

No

No

2 of 14

No

No

2 of 14

No

No

2 of 14

No

No

2 of 14

No

No

2 of 14

No

No

2 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

Yes

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

Drer\si:dkey-43p13.5

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

Drer\zgc:101100

1 of 14

No

No

Caenorhabditis elegans (Nematode, roundworm) (54)

2 of 14

Yes

No

2 of 14

Yes

No

2 of 14

Yes

No

2 of 14

Yes

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

0

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

1

1 of 14

No

No

1 of 14

No

No

1 of 14

No

No

Anopheles gambiae (African malaria mosquito) (61)

Agam\AgaP_AGAP003674

12 of 12

Yes

Yes

Agam\AgaP_AGAP000484

2 of 12

No

No

Agam\AgaP_AGAP001389

2 of 12

No

No

Agam\AgaP_AGAP005727

2 of 12

No

No

Agam\AgaP_AGAP012428

2 of 12

No

No

Agam\AgaP_AGAP013373

2 of 12

No

No

Agam\ABDA_ANOGA

1 of 12

No

No

Agam\AgaP_AGAP000063

1 of 12

No

No

Agam\AgaP_AGAP000067

1 of 12

No

No

Agam\AgaP_AGAP000190

1 of 12

No

No

Agam\AgaP_AGAP000488

1 of 12

No

No

Agam\AgaP_AGAP001187

1 of 12

No

No

Agam\AgaP_AGAP001483

1 of 12

No

No

Agam\AgaP_AGAP001495

1 of 12

No

No

Agam\AgaP_AGAP001560

1 of 12

No

No

Agam\AgaP_AGAP001593

1 of 12

No

No

Agam\AgaP_AGAP001618

1 of 12

No

No

Agam\AgaP_AGAP001619

1 of 12

No

No

Agam\AgaP_AGAP002372

1 of 12

No

No

Agam\AgaP_AGAP002431

1 of 12

No

No

Agam\AgaP_AGAP003669

1 of 12

No

No

Agam\AgaP_AGAP003670

1 of 12

No

No

Agam\AgaP_AGAP003671

1 of 12

No

No

Agam\AgaP_AGAP003672

1 of 12

No

No

Agam\AgaP_AGAP004646

1 of 12

No

No

Agam\AgaP_AGAP004647

1 of 12

No

No

Agam\AgaP_AGAP004648

1 of 12

No

No

Agam\AgaP_AGAP004649

1 of 12

No

No

Agam\AgaP_AGAP004659

1 of 12

No

No

Agam\AgaP_AGAP004660

1 of 12

No

No

Agam\AgaP_AGAP004661

1 of 12

No

No

Agam\AgaP_AGAP005010

1 of 12

No

No

Agam\AgaP_AGAP005041

1 of 12

No

No

Agam\AgaP_AGAP005096

1 of 12

No

No

Agam\AgaP_AGAP005099

1 of 12

No

No

Agam\AgaP_AGAP005137

1 of 12

No

No

Agam\AgaP_AGAP005281

1 of 12

No

No

Agam\AgaP_AGAP005311

1 of 12

No

No

Agam\AgaP_AGAP005346

1 of 12

No

No

Agam\AgaP_AGAP006536

1 of 12

No

No

Agam\AgaP_AGAP006537

1 of 12

No

No

Agam\AgaP_AGAP006540

1 of 12

No

No

Agam\AgaP_AGAP006923

1 of 12

No

No

Agam\AgaP_AGAP007058

1 of 12

No

No

Agam\AgaP_AGAP007985

1 of 12

No

No

Agam\AgaP_AGAP009088

1 of 12

No

No

Agam\AgaP_AGAP009302

1 of 12

No

No

Agam\AgaP_AGAP009500

1 of 12

No

No

Agam\AgaP_AGAP009646

1 of 12

No

No

Agam\AgaP_AGAP010209

1 of 12

No

No

Agam\AgaP_AGAP010279

1 of 12

No

No

Agam\AgaP_AGAP010358

1 of 12

No

No

Agam\AgaP_AGAP010359

1 of 12

No

No

Agam\AgaP_AGAP011134

1 of 12

No

No

Agam\AgaP_AGAP011253

1 of 12

No

No

Agam\AgaP_AGAP011417

1 of 12

No

No

Agam\AgaP_AGAP012001

1 of 12

No

No

Agam\AgaP_AGAP013075

1 of 12

No

No

Agam\AgaP_AGAP013157

1 of 12

No

No

1 of 12

No

No

Agam\HMEN_ANOGA

1 of 12

No

No

Arabidopsis thaliana (thale-cress) (48)

3 of 13

Yes

No

3 of 13

Yes

No

3 of 13

Yes

No

2 of 13

No

Yes

2 of 13

No

No

2 of 13

No

No

2 of 13

No

No

2 of 13

No

No

2 of 13

No

No

2 of 13

No

No

2 of 13

No

No

2 of 13

No

No

2 of 13

No

No

2 of 13

No

No

2 of 13

No

No

2 of 13

No

No

2 of 13

No

No

2 of 13

No

No

2 of 13

No

No

2 of 13

No

No

2 of 13

No

No

2 of 13

No

No

2 of 13

No

No

2 of 13

No

No

2 of 13

No

No

1 of 13

No

No

1 of 13

No

Yes

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

Yes

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

Saccharomyces cerevisiae (Brewer's yeast) (3)

1 of 13

Yes

Yes

1 of 13

Yes

No

1 of 13

Yes

No

Schizosaccharomyces pombe (Fission yeast) (2)

2 of 12

Yes

No

1 of 12

No

No

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:C15. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (86)

4 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

3 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

TLX3; T cell leukemia homeobox 3

11 of 14

TLX1; T cell leukemia homeobox 1

10 of 14

TLX2; T cell leukemia homeobox 2

10 of 14

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

two hybrid array

(Shokri et al., 2019)

two hybrid array

(Shokri et al., 2019)

anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based

(Rhee et al., 2014)

pull down, autoradiography

(Mojica-Vázquez et al., 2017)

two hybrid array

(Shokri et al., 2019)

two hybrid array

(Shokri et al., 2019)

two hybrid array

(Shokri et al., 2019)

two hybrid array

(Shokri et al., 2019)

anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based

(Rhee et al., 2014)

bimolecular fluorescence complementation, fluorescence microscopy

(Bischof et al., 2018)

bimolecular fluorescence complementation, fluorescence microscopy

(Bischof et al., 2018)

pull down, autoradiography, western blot, x-ray crystallography

(Mojica-Vázquez et al., 2017, Miyazono et al., 2010, Kojima et al., 2005)

two hybrid array

(Shokri et al., 2019)

C15 - l(2)k10201

two hybrid array

(Shokri et al., 2019)

two hybrid array

(Shokri et al., 2019)

anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based

(Rhee et al., 2014)

two hybrid array

(Shokri et al., 2019)

Summary of Genetic Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

enhanceable

(Campbell, 2005)

External Data

Linkouts

BioGRID - A database of protein and genetic interactions.

67510

DroID - A comprehensive database of gene and protein interactions.

FBgn0004863

MIST (protein-protein) - An integrated Molecular Interaction Database

42544

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

Class of Gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

3R

Recombination map

3-72

Cytogenetic map

Sequence location

3R:21,499,986..21,512,814 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

93E3-93E4

Limits computationally determined from genome sequence between P{PZ}mod(mdg4)⁰⁷⁰³⁸&P{lacW}mod(mdg4)^L3101 and P{PZ}InR⁰⁵⁵⁴⁵;

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

93E1-93F8

(Kojima et al., 2005)

93C3-93F

(Campbell, 2005)

93E-93E

(Dear, 1993.6.4)

93E-93E

(determined by in situ hybridisation)

(Dear and Rabbitts, 1994)

93E1-93E2

(Dessain and McGinnis, 1993)

Location based on deficiency mapping.

(Campbell, 2005)

Experimentally Determined Recombination Data

Location

3-72

(FlyBase, 2016)

3-74.4

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (22)

Aberrations including deletions of this gene Aberrations including duplications of this gene

59028

C15²/TM6B, Tb¹

41233

w¹¹¹⁸; P{GMR40B01-GAL4}attP2

50056

w¹¹¹⁸; P{GMR39F05-GAL4}attP2

50087

w¹¹¹⁸; P{GMR40E04-GAL4}attP2

89613

w¹¹¹⁸; P{R40B01-p65.AD}JK22C

69846

w¹¹¹⁸; P{R39F05-GAL4.DBD}attP2

59029

C15³ e¹/TM6B, Tb¹

F003372

M{UAS-C15.ORF-CC}ZH-21F

F001697

M{UAS-C15.ORF.3xHA.GW}ZH-86Fb

v330706

P{VSH330706}attP40

v107334

P{KK109374}VIE-260B

v318356

PBac{fTRG01385.sfGFP-TVPTBF}VK00033

More stocks available...

Genomic Clones (33)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (8)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

Other clones

FI01111

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0004863

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0004863

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

Location based on deficiency mapping. Overall orientation not stated: lbe- CG7922+ C15+ CG7056+

(Kojima et al., 2005)

In situ and antibody staining show that C15 is expressed in amnioserosa cells, from cellularized blastoderm until the amnioserosa degenerates in late embryogenesis. From stage 11 on, there is also expression in small, segmentally repeated clusters of neurons of the CNS and in sensory cells of the Keilin's organs and of the antenno-maxillary complex.

(Frasch, 1995.3.24)

C15 has been cloned and sequenced.

(Dear and Rabbitts, 1994)

Relationship to Other Genes

Source for database merge of

Additional comments

Nomenclature History

Source for database identify of

Nomenclature comments

Etymology

Synonyms and Secondary IDs (10)

Reported As

Symbol Synonym

311

(Dear and Rabbitts, 1994)

93Bal

C15

(Janssens et al., 2025, Gurgo et al., 2024, Petrosky et al., 2024, Floc'hlay et al., 2023, Bourbon et al., 2022, Pegoraro et al., 2022, Xie et al., 2021, Mahmud et al., 2020, Shokri et al., 2019, Xie et al., 2019, Bischof et al., 2018, Newcomb et al., 2018, Ruiz-Losada et al., 2018, Karaiskos et al., 2017, Li et al., 2017, Ly et al., 2017, Mojica-Vázquez et al., 2017, Transgenic RNAi Project members, 2017-, Bürglin and Affolter, 2016, Dominguez et al., 2016, Kalay et al., 2016, Sarov et al., 2016, model organism Encyclopedia of Regulatory Network (modERN) Project, 2015-, Schertel et al., 2015, Gonzalez et al., 2014, Li et al., 2013, Saunders et al., 2013, Liang et al., 2012, Bantignies et al., 2011, Cherbas et al., 2011, Guest et al., 2011, Nien et al., 2011, Bosch et al., 2010, Chopra et al., 2009, Hazelett et al., 2009, Liu et al., 2009, Liu et al., 2008, Liang et al., 2007, Tajiri et al., 2007, Lin et al., 2006, Sandmann et al., 2006, Yasunaga et al., 2006, Copley, 2005, Hoskins et al., 2005)

CG7937

(Meadows, 2019.11.20, Meadows, 2018.10.31, Ni et al., 2011.7.19, Keleman et al., 2009.8.5, Perkins et al., 2009)

Cll

(Kachhap et al., 2017, Bürglin and Affolter, 2016, Tajiri et al., 2007, Takahashi et al., 2005)

Ect5

(Stathopoulos et al., 2002)

Hox11-311

c15

(Liu et al., 2008)

cll

(Miyazono et al., 2010, Tajiri et al., 2007, Yasunaga et al., 2006, Kojima et al., 2005)

Name Synonyms

C15

clawless

(Miyazono et al., 2010, Tajiri et al., 2007, Yasunaga et al., 2006, Kojima et al., 2005)

Secondary FlyBase IDs

FBgn0002943
FBgn0008640
FBgn0010393

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 38 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

42544

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

Q7KS72

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

Q7KS72

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0004863

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

42544/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0004863

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0004863

FlyMine - An integrated database for Drosophila genomics

FBgn0004863

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG7937

MARRVEL_MODEL - MARRVEL (model organism gene)

42544

PDB - An information portal to biological macromolecular structures

3A01

Linkouts

BioGRID - A database of protein and genetic interactions.

67510

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0004863

DroID - A comprehensive database of gene and protein interactions.

FBgn0004863

DRSC - Results frm RNAi screens

FBgn0004863

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

C15_1

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0004863

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0004863

Flygut - An atlas of the Drosophila adult midgut

FBgn0004863

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC011749

Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution

Interactive Fly

MIST (protein-protein) - An integrated Molecular Interaction Database

42544

References (94)