FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Gene: Dmel\Pph13
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General Information
Symbol
Dmel\Pph13
Species
D. melanogaster
Name
PvuII-PstI homology 13
Annotation Symbol
CG2819
Feature Type
protein_coding_gene
FlyBase ID
FBgn0023489
Gene Model Status
Current
Stock Availability
14 publicly available
Gene Summary
PvuII-PstI homology 13 (Pph13) encodes a paired-class homeodomain protein. It is critical for rhabdomeric photoreceptor differentiation, phototransduction and rhabdomere morphogenesis. [Date last reviewed: 2019-03-14] (FlyBase Gene Snapshot)
All Summaries
Also Known As

Munster, hazy, Mu

Key Links
Genomic Location
Cytogenetic map
21E2-21E2
Sequence location
Recombination map
2-1.5
RefSeq locus
NT_033779 REGION:577486..579549
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
Gene Ontology (GO) Annotations (15 terms)
Molecular Function (5 terms)
Terms Based on Experimental Evidence (3 terms)
CV Term
Evidence
References
enables DNA-binding transcription activator activity, RNA polymerase II-specific
inferred from direct assay
(Mishra et al., 2010, Zelhof et al., 2003)
enables protein homodimerization activity
inferred from direct assay
(Mishra et al., 2010)
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding
inferred from direct assay
(Mishra et al., 2010, Zelhof et al., 2003)
Terms Based on Predictions or Assertions (3 terms)
CV Term
Evidence
References
enables DNA binding
inferred from electronic annotation with InterPro:IPR001356
(InterPro Project Members, 2004-)
enables DNA-binding transcription factor activity, RNA polymerase II-specific
inferred from electronic annotation with InterPro:IPR017970
(InterPro Project Members, 2004-)
inferred from biological aspect of ancestor with PANTHER:PTN004692309
(GO Reference Genome Project, 2011-)
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding
inferred from biological aspect of ancestor with PANTHER:PTN004692309
(GO Reference Genome Project, 2011-)
Biological Process (9 terms)
Terms Based on Experimental Evidence (6 terms)
CV Term
Evidence
References
involved_in compound eye photoreceptor development
inferred from mutant phenotype
(Mishra et al., 2010)
involved_in ocellus photoreceptor cell development
inferred from genetic interaction with FLYBASE:oc; FB:FBgn0004102
(Mishra et al., 2010)
involved_in photoreceptor cell development
inferred from mutant phenotype
(Bernardo-Garcia et al., 2017)
involved_in positive regulation of DNA-templated transcription
inferred from direct assay
(Mishra et al., 2010)
involved_in positive regulation of transcription by RNA polymerase II
inferred from direct assay
(Mishra et al., 2010, Zelhof et al., 2003)
involved_in rhabdomere development
inferred from mutant phenotype
(Mishra et al., 2010, Zelhof et al., 2003)
Terms Based on Predictions or Assertions (3 terms)
CV Term
Evidence
References
involved_in neuron development
inferred from biological aspect of ancestor with PANTHER:PTN001216073
(GO Reference Genome Project, 2011-)
involved_in regulation of DNA-templated transcription
inferred from electronic annotation with InterPro:IPR017970
(InterPro Project Members, 2004-)
involved_in regulation of transcription by RNA polymerase II
inferred from biological aspect of ancestor with PANTHER:PTN004692309
(GO Reference Genome Project, 2011-)
Cellular Component (1 term)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
located_in nucleus
inferred from direct assay
(Zelhof et al., 2003)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
is_active_in nucleus
inferred from biological aspect of ancestor with PANTHER:PTN004692309
(GO Reference Genome Project, 2011-)
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Summaries
Gene Snapshot
PvuII-PstI homology 13 (Pph13) encodes a paired-class homeodomain protein. It is critical for rhabdomeric photoreceptor differentiation, phototransduction and rhabdomere morphogenesis. [Date last reviewed: 2019-03-14]
Gene Group (FlyBase)
PAIRED-LIKE HOMEOBOX TRANSCRIPTION FACTORS -
Paired-like (PRD-like) homeobox transcription factors are sequence-specific DNA binding proteins that regulate transcription. PRD-like transcription factors lack a paired domain but possess a homeodomain characteristic of the paired homeobox transcription factors. Some members also possess an Engrailed Homology 1 (EH1) and/or an OAR motif near the C-terminus. (Adapted from FBrf0232555 and FBrf0106517).
Summary (Interactive Fly)

homeodomain transcription expressed in the developing eye - required for rhabdomere morphogenesis and proper detection of light

Gene Model and Products
Number of Transcripts
1
Number of Unique Polypeptides
1

Please see the JBrowse view of Dmel\Pph13 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Structure
Protein 3D structure   (Predicted by AlphaFold)   (AlphaFold entry Q9XZU0)

If you don't see a structure in the viewer, refresh your browser.
Model Confidence:
  • Very high (pLDDT > 90)
  • Confident (90 > pLDDT > 70)
  • Low (70 > pLDDT > 50)
  • Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures
Crossreferences
Comments on Gene Model

Gene model reviewed during 5.42

Gene model reviewed during 5.46

Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
Pph13-RA
FBtr0078070
NM_057982
1880
357
Additional Transcript Data and Comments
Reported size (kB)

1.9 (longest cDNA)

(Goriely et al., 1999)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
UniProt
RefSeq ID
GenBank
Pph13-PA
FBpp0077730
39.3
357
4.89
Q9XZU0
NP_477330
AAF51474
Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments
Reported size (kDa)

357 (aa)

(Goriely et al., 1999)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Pph13 using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.61

Transcript Expression
expression microarray
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
eye
(Xu et al., 2004)
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 11 -- 12
Bolwig organ primordium

Comment: reported as larval eye primordium

(Fisher et al., 2012)
embryonic stage 12 -- 17
Bolwig organ | precursor
(Goriely et al., 1999)
embryonic stage 13 -- 16
Bolwig organ
(Fisher et al., 2012)
embryonic stage 17
Bolwig organ | presumptive
(Goriely et al., 1999)
adult stage
eye
(Goriely et al., 1999)
medulla
(Goriely et al., 1999)
photoreceptor neuron of retina
(Goriely et al., 1999)
lamina
(Goriely et al., 1999)
Additional Descriptive Data

Eye-enriched transcripts determined by ratio of expression level in wild-type heads. versus expression level in so heads.

(Xu et al., 2004)
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
immunolocalization
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 15
Bolwig organ primordium
(Mishra et al., 2013)
embryonic stage 16
Bolwig organ
(Zelhof et al., 2003)
third instar larval stage
Bolwig organ primordium
(Mishra et al., 2013)
photoreceptor neuron
(Mishra et al., 2016)
pupal stage P7 -- adult stage
photoreceptor neuron
(Zelhof et al., 2003)
adult stage
eyelet
(Mishra et al., 2013)
ocellar retinula cell
(Mishra et al., 2016)
Additional Descriptive Data

Pph13 protein is expressed at late embryonic stages in the cells of the Bolwig organ, and in no other embryonic tissues. There is no expression in the imaginal discs, including eye discs, during larval stages. Pupal expression begins at 36 hours APF; during pupal development, Pph13 protein is expressed in all eight photoreceptor cells. This pattern is maintained in the adult eye.

(Zelhof et al., 2003)
Marker for
 
Subcellular Localization
CV Term
Evidence
References
located_in nucleus
inferred from direct assay
(Zelhof et al., 2003)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\Pph13 in JBrowse
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyExpress - Embryonic expression images (BDGP data)
  • Stages(s) 13-16
FlyBase Wiki
Image Based Resources
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 3 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 14 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of Pph13
Transgenic constructs containing regulatory region of Pph13
Aberrations (Deficiencies and Duplications) ( 13 )
Variants
Variant Molecular Consequences
Alleles Representing Disease-Implicated Variants
Phenotypes
Orthologs
Downloads
Download All DIOPT Orthologs
Human Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Homo sapiens (Human) (150)
Hsap\ALX1
5 of 14
Yes
Yes
Hsap\ALX3
5 of 14
Yes
Yes
Hsap\ALX4
5 of 14
Yes
Yes
Hsap\ARX
5 of 14
Yes
No
Hsap\DRGX
3 of 14
No
No
Hsap\ISX
3 of 14
No
Yes
Hsap\RAX2
3 of 14
No
No
Hsap\RAX
3 of 14
No
No
1  
Hsap\CRX
2 of 14
No
No
5  
Hsap\ESX1
2 of 14
No
No
Hsap\GSC2
2 of 14
No
No
Hsap\GSC
2 of 14
No
No
Hsap\MIXL1
2 of 14
No
No
Hsap\OTX1
2 of 14
No
No
3  
Hsap\OTX2
2 of 14
No
No
3  
Hsap\PAX3
2 of 14
No
No
1  
Hsap\PAX7
2 of 14
No
No
0  
Hsap\PHOX2A
2 of 14
No
No
Hsap\PHOX2B
2 of 14
No
No
Hsap\PITX1
2 of 14
No
No
3  
Hsap\PITX2
2 of 14
No
No
1  
Hsap\PITX3
2 of 14
No
No
1  
Hsap\PROP1
2 of 14
No
Yes
Hsap\PRRX1
2 of 14
No
No
Hsap\PRRX2
2 of 14
No
No
Hsap\RHOXF1
2 of 14
No
No
Hsap\SHOX2
2 of 14
No
No
Hsap\SHOX
2 of 14
No
No
1  
Hsap\ABLIM1
1 of 14
No
No
Hsap\ABLIM2
1 of 14
No
No
1  
Hsap\ARGFX
1 of 14
No
Yes
Hsap\BARHL1
1 of 14
No
No
Hsap\BARHL2
1 of 14
No
No
Hsap\BARX1
1 of 14
No
No
Hsap\BARX2
1 of 14
No
No
Hsap\BSX
1 of 14
No
No
Hsap\CDX4
1 of 14
No
No
Hsap\CPHXL
1 of 14
No
No
Hsap\CUX1
1 of 14
No
No
1  
Hsap\DBX1
1 of 14
No
No
Hsap\DBX2
1 of 14
No
No
Hsap\DLX1
1 of 14
No
No
Hsap\DLX2
1 of 14
No
No
Hsap\DLX3
1 of 14
No
No
1  
Hsap\DLX4
1 of 14
No
No
1  
Hsap\DLX5
1 of 14
No
No
Hsap\DLX6
1 of 14
No
No
Hsap\DMBX1
1 of 14
No
No
Hsap\DPRX
1 of 14
No
Yes
Hsap\DUX1
1 of 14
No
Yes
Hsap\DUX3
1 of 14
No
Yes
Hsap\DUX4
1 of 14
No
No
2  
Hsap\DUX4L4
1 of 14
No
Yes
Hsap\DUX4L7
1 of 14
No
Yes
Hsap\DUX4L9
1 of 14
No
Yes
Hsap\DUX5
1 of 14
No
Yes
Hsap\DUXA
1 of 14
No
Yes
Hsap\DUXB
1 of 14
No
Yes
Hsap\EMX1
1 of 14
No
No
Hsap\EMX2
1 of 14
No
No
Hsap\GBX1
1 of 14
No
No
Hsap\GBX2
1 of 14
No
No
1  
Hsap\GSX1
1 of 14
No
No
Hsap\GSX2
1 of 14
No
No
Hsap\HESX1
1 of 14
No
Yes
Hsap\HHEX
1 of 14
No
No
Hsap\HLX
1 of 14
No
No
Hsap\HMX2
1 of 14
No
No
Hsap\HOXA1
1 of 14
No
No
Hsap\HOXA3
1 of 14
No
No
Hsap\HOXA4
1 of 14
No
No
Hsap\HOXA5
1 of 14
No
No
1  
Hsap\HOXA6
1 of 14
No
No
Hsap\HOXA7
1 of 14
No
No
Hsap\HOXA10
1 of 14
No
No
1  
Hsap\HOXA13
1 of 14
No
No
Hsap\HOXB1
1 of 14
No
No
Hsap\HOXB2
1 of 14
No
No
1  
Hsap\HOXB3
1 of 14
No
No
Hsap\HOXB4
1 of 14
No
No
Hsap\HOXB5
1 of 14
No
No
1  
Hsap\HOXB7
1 of 14
No
No
Hsap\HOXB8
1 of 14
No
No
Hsap\HOXC4
1 of 14
No
No
Hsap\HOXC5
1 of 14
No
No
Hsap\HOXC8
1 of 14
No
No
1  
Hsap\HOXC10
1 of 14
No
No
1  
Hsap\HOXC11
1 of 14
No
No
Hsap\HOXD1
1 of 14
No
No
Hsap\HOXD3
1 of 14
No
No
Hsap\HOXD13
1 of 14
No
No
Hsap\ISL1
1 of 14
No
No
Hsap\ISL2
1 of 14
No
No
1  
Hsap\LBX1
1 of 14
No
No
Hsap\LBX2
1 of 14
No
No
2  
Hsap\LEUTX
1 of 14
No
No
Hsap\LHX1
1 of 14
No
No
1  
Hsap\LHX2
1 of 14
No
No
1  
Hsap\LHX3
1 of 14
No
No
Hsap\LHX4
1 of 14
No
No
Hsap\LHX5
1 of 14
No
No
Hsap\LHX6
1 of 14
No
No
1  
Hsap\LHX8
1 of 14
No
No
Hsap\LHX9
1 of 14
No
No
1  
Hsap\LMO1
1 of 14
No
No
1  
Hsap\LMX1A
1 of 14
No
No
Hsap\LMX1B
1 of 14
No
No
Hsap\LOC112268164
1 of 14
No
Yes
Hsap\LPP
1 of 14
No
No
1  
Hsap\MEOX1
1 of 14
No
No
1  
Hsap\MEOX2
1 of 14
No
No
Hsap\MNX1
1 of 14
No
No
Hsap\MSX1
1 of 14
No
No
Hsap\MSX2
1 of 14
No
No
Hsap\NANOGP1
1 of 14
No
Yes
Hsap\NKX1-2
1 of 14
No
No
Hsap\NKX2-2
1 of 14
No
No
Hsap\NKX2-4
1 of 14
No
No
Hsap\NKX2-5
1 of 14
No
No
Hsap\NKX2-6
1 of 14
No
No
Hsap\NKX3-1
1 of 14
No
No
Hsap\NKX3-2
1 of 14
No
No
Hsap\NKX6-1
1 of 14
No
No
1  
Hsap\NKX6-2
1 of 14
No
No
Hsap\NKX6-3
1 of 14
No
No
Hsap\NOBOX
1 of 14
No
No
Hsap\NOTO
1 of 14
No
No
Hsap\OTP
1 of 14
No
No
Hsap\PAX4
1 of 14
No
No
Hsap\PAX6
1 of 14
No
No
2  
Hsap\PDLIM7
1 of 14
No
No
Hsap\PDX1
1 of 14
No
No
Hsap\POU2F3
1 of 14
No
No
1  
Hsap\PRICKLE3
1 of 14
No
No
1  
Hsap\RHOXF2B
1 of 14
No
No
Hsap\RHOXF2
1 of 14
No
No
Hsap\SEBOX
1 of 14
No
Yes
Hsap\TLX1
1 of 14
No
No
Hsap\TLX2
1 of 14
No
No
Hsap\TLX3
1 of 14
No
No
Hsap\TPRX1
1 of 14
No
No
Hsap\TRIP6
1 of 14
No
No
1  
Hsap\UNCX
1 of 14
No
No
Hsap\VAX2
1 of 14
No
No
Hsap\VENTX
1 of 14
No
No
Hsap\VSX1
1 of 14
No
No
1  
Hsap\VSX2
1 of 14
No
No
1  
Hsap\WTIP
1 of 14
No
No
1  
Hsap\ZFHX3
1 of 14
No
No
1  
Hsap\ZFHX4
1 of 14
No
No
Model Organism Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Rattus norvegicus (Norway rat) (95)
Rnor\Alx1
5 of 14
Yes
Yes
Rnor\Alx3
5 of 14
Yes
Yes
Rnor\Alx4
5 of 14
Yes
Yes
Rnor\Arx
4 of 14
No
No
Rnor\Drgx
3 of 14
No
No
Rnor\Isx
3 of 14
No
Yes
Rnor\Rax
3 of 14
No
No
Rnor\Crx
2 of 14
No
No
Rnor\Gsc2
2 of 14
No
No
Rnor\Gsc
2 of 14
No
No
Rnor\Mixl1
2 of 14
No
No
Rnor\Nobox
2 of 14
No
Yes
Rnor\Otx1
2 of 14
No
No
Rnor\Pax3
2 of 14
No
No
Rnor\Pax7
2 of 14
No
No
Rnor\Phox2a
2 of 14
No
No
Rnor\Phox2b
2 of 14
No
No
Rnor\Pitx1
2 of 14
No
No
Rnor\Pitx2
2 of 14
No
No
Rnor\Pitx3
2 of 14
No
No
Rnor\Prop1
2 of 14
No
Yes
Rnor\Prrx1
2 of 14
No
No
Rnor\Prrx2
2 of 14
No
No
Rnor\Rhox11
2 of 14
No
Yes
Rnor\Rhox13
2 of 14
No
Yes
Rnor\Shox2
2 of 14
No
No
Rnor\Barhl1
1 of 14
No
No
Rnor\Barhl2
1 of 14
No
No
Rnor\Barx1
1 of 14
No
No
Rnor\Bsx
1 of 14
No
No
Rnor\Cdx2
1 of 14
No
No
Rnor\Cdx4
1 of 14
No
No
Rnor\Cphx1
1 of 14
No
Yes
Rnor\Cux1
1 of 14
No
No
Rnor\Dbx2
1 of 14
No
No
Rnor\Dlx3
1 of 14
No
No
Rnor\Dlx4
1 of 14
No
No
Rnor\Dlx5
1 of 14
No
No
Rnor\Dlx6
1 of 14
No
No
Rnor\Dmbx1
1 of 14
No
No
Rnor\Dux4
1 of 14
No
No
Rnor\Emx1
1 of 14
No
No
Rnor\Emx2
1 of 14
No
No
Rnor\Gbx2
1 of 14
No
No
Rnor\Hhex
1 of 14
No
No
Rnor\Hlx
1 of 14
No
No
Rnor\Hmx2
1 of 14
No
No
Rnor\Hoxa1
1 of 14
No
No
Rnor\Hoxa3
1 of 14
No
Yes
Rnor\Hoxa6
1 of 14
No
No
Rnor\Hoxb1
1 of 14
No
No
Rnor\Hoxb3
1 of 14
No
No
Rnor\Hoxb5
1 of 14
No
No
Rnor\Hoxb6
1 of 14
No
No
Rnor\Hoxd13
1 of 14
No
Yes
Rnor\Isl2
1 of 14
No
No
Rnor\Lbx1
1 of 14
No
No
Rnor\Lbx2
1 of 14
No
No
Rnor\Lhx2
1 of 14
No
No
Rnor\Lhx3
1 of 14
No
No
Rnor\Lhx4
1 of 14
No
No
Rnor\Lhx5
1 of 14
No
No
Rnor\Lhx9
1 of 14
No
No
Rnor\LOC691325
1 of 14
No
No
Rnor\LOC100364002
1 of 14
No
No
Rnor\LOC102553890
1 of 14
No
Yes
Rnor\Meox2
1 of 14
No
No
Rnor\Msx1
1 of 14
No
No
Rnor\Msx2
1 of 14
No
No
Rnor\Nanog
1 of 14
No
No
Rnor\Nkx2-2
1 of 14
No
No
Rnor\Nkx2-3
1 of 14
No
No
Rnor\Nkx2-5
1 of 14
No
No
Rnor\Nkx3-1
1 of 14
No
No
Rnor\Nkx6-1
1 of 14
No
No
Rnor\Nkx6-2
1 of 14
No
No
Rnor\Nkx6-3
1 of 14
No
No
Rnor\Noto
1 of 14
No
No
Rnor\Obox2
1 of 14
No
Yes
Rnor\Otx2
1 of 14
No
No
Rnor\Pax4
1 of 14
No
No
Rnor\Pax6
1 of 14
No
No
Rnor\Rhox2
1 of 14
No
Yes
Rnor\Rhox3
1 of 14
No
Yes
Rnor\Rhox4g
1 of 14
No
Yes
Rnor\Rhox8
1 of 14
No
No
Rnor\Rhox10
1 of 14
No
No
Rnor\Rhox12
1 of 14
No
No
Rnor\Sebox
1 of 14
No
Yes
Rnor\Tlx2
1 of 14
No
No
Rnor\Uncx
1 of 14
No
No
Rnor\Vax2
1 of 14
No
No
Rnor\Vsx1
1 of 14
No
No
Rnor\Zfhx3
1 of 14
No
No
Rnor\Zfhx4
1 of 14
No
No
Mus musculus (laboratory mouse) (128)
Mmus\Alx1
5 of 14
Yes
Yes
Mmus\Alx3
5 of 14
Yes
Yes
Mmus\Arx
5 of 14
Yes
No
Mmus\Alx4
4 of 14
No
Yes
Mmus\Isx
3 of 14
No
Yes
Mmus\Prrxl1
3 of 14
No
No
Mmus\Rax
3 of 14
No
No
Mmus\Crx
2 of 14
No
No
Mmus\Gsc2
2 of 14
No
No
Mmus\Gsc
2 of 14
No
No
Mmus\Mixl1
2 of 14
No
No
Mmus\Obox8
2 of 14
No
Yes
Mmus\Otx1
2 of 14
No
No
Mmus\Otx2
2 of 14
No
No
Mmus\Pax3
2 of 14
No
No
1  
Mmus\Pax7
2 of 14
No
No
Mmus\Phox2a
2 of 14
No
No
Mmus\Phox2b
2 of 14
No
No
Mmus\Pitx1
2 of 14
No
No
Mmus\Pitx2
2 of 14
No
No
Mmus\Pitx3
2 of 14
No
No
Mmus\Prop1
2 of 14
No
No
Mmus\Prrx1
2 of 14
No
No
Mmus\Prrx2
2 of 14
No
No
Mmus\Rhox13
2 of 14
No
Yes
Mmus\Shox2
2 of 14
No
No
Mmus\Barhl1
1 of 14
No
No
Mmus\Barhl2
1 of 14
No
No
Mmus\Barx1
1 of 14
No
No
Mmus\Bsx
1 of 14
No
No
Mmus\Cdx2
1 of 14
No
No
Mmus\Cdx4
1 of 14
No
No
Mmus\Cphx1
1 of 14
No
No
Mmus\Crxos
1 of 14
No
Yes
Mmus\Cux1
1 of 14
No
No
Mmus\Dbx2
1 of 14
No
No
Mmus\Dlx1
1 of 14
No
No
Mmus\Dlx2
1 of 14
No
No
Mmus\Dlx3
1 of 14
No
No
Mmus\Dlx5
1 of 14
No
No
Mmus\Dlx6
1 of 14
No
No
Mmus\Dmbx1
1 of 14
No
No
Mmus\Duxbl1
1 of 14
No
No
Mmus\Duxf3
1 of 14
No
Yes
Mmus\Emx1
1 of 14
No
No
Mmus\Emx2
1 of 14
No
No
1  
Mmus\Gbx2
1 of 14
No
No
Mmus\Gm9376
1 of 14
No
Yes
Mmus\Hhex
1 of 14
No
No
Mmus\Hlx
1 of 14
No
No
Mmus\Hmx2
1 of 14
No
No
Mmus\Hoxa1
1 of 14
No
No
Mmus\Hoxa3
1 of 14
No
No
Mmus\Hoxa4
1 of 14
No
No
Mmus\Hoxa6
1 of 14
No
No
Mmus\Hoxb1
1 of 14
No
No
0  
Mmus\Hoxb3
1 of 14
No
No
0  
Mmus\Hoxb5
1 of 14
No
No
Mmus\Hoxb6
1 of 14
No
No
1  
Mmus\Hoxb7
1 of 14
No
No
Mmus\Hoxd3
1 of 14
No
No
Mmus\Hoxd13
1 of 14
No
Yes
Mmus\Isl2
1 of 14
No
No
Mmus\Lbx1
1 of 14
No
No
Mmus\Lbx2
1 of 14
No
No
Mmus\Lhx2
1 of 14
No
No
Mmus\Lhx3
1 of 14
No
No
Mmus\Lhx4
1 of 14
No
No
Mmus\Lhx5
1 of 14
No
No
Mmus\Lhx9
1 of 14
No
No
Mmus\LOC100504180
1 of 14
No
Yes
Mmus\Meox2
1 of 14
No
No
Mmus\Msx1
1 of 14
No
No
Mmus\Msx2
1 of 14
No
No
0  
Mmus\Msx3
1 of 14
No
No
Mmus\Nanog
1 of 14
No
No
Mmus\Nkx2-2
1 of 14
No
No
Mmus\Nkx2-5
1 of 14
No
No
5  
Mmus\Nkx2-6
1 of 14
No
No
Mmus\Nkx6-1
1 of 14
No
No
Mmus\Nkx6-2
1 of 14
No
No
Mmus\Nkx6-3
1 of 14
No
No
Mmus\Nobox
1 of 14
No
No
Mmus\Noto
1 of 14
No
No
Mmus\Obox6
1 of 14
No
No
Mmus\Pax4
1 of 14
No
No
Mmus\Pax6
1 of 14
No
No
3  
Mmus\Pbx4
1 of 14
No
No
Mmus\Rhox1
1 of 14
No
Yes
Mmus\Rhox2a
1 of 14
No
Yes
Mmus\Rhox2b
1 of 14
No
Yes
Mmus\Rhox2c
1 of 14
No
Yes
Mmus\Rhox2d
1 of 14
No
Yes
Mmus\Rhox2e
1 of 14
No
Yes
Mmus\Rhox2f
1 of 14
No
Yes
Mmus\Rhox2g
1 of 14
No
Yes
Mmus\Rhox2h
1 of 14
No
Yes
Mmus\Rhox3a2
1 of 14
No
Yes
Mmus\Rhox3a
1 of 14
No
Yes
Mmus\Rhox3c
1 of 14
No
Yes
Mmus\Rhox3e
1 of 14
No
Yes
Mmus\Rhox3f
1 of 14
No
Yes
Mmus\Rhox3g
1 of 14
No
Yes
Mmus\Rhox3h
1 of 14
No
Yes
Mmus\Rhox4a2
1 of 14
No
Yes
Mmus\Rhox4a
1 of 14
No
Yes
Mmus\Rhox4b
1 of 14
No
Yes
Mmus\Rhox4c
1 of 14
No
Yes
Mmus\Rhox4d
1 of 14
No
Yes
Mmus\Rhox4e
1 of 14
No
Yes
Mmus\Rhox4f
1 of 14
No
Yes
Mmus\Rhox4g
1 of 14
No
Yes
Mmus\Rhox6
1 of 14
No
Yes
Mmus\Rhox7a
1 of 14
No
Yes
Mmus\Rhox7b
1 of 14
No
Yes
Mmus\Rhox9
1 of 14
No
Yes
Mmus\Rhox10
1 of 14
No
No
Mmus\Rhox11
1 of 14
No
No
Mmus\Rhox12
1 of 14
No
Yes
Mmus\Sebox
1 of 14
No
Yes
Mmus\Tlx1
1 of 14
No
No
Mmus\Tlx2
1 of 14
No
No
Mmus\Uncx
1 of 14
No
No
Mmus\Vax2
1 of 14
No
No
Mmus\Vsx1
1 of 14
No
No
Mmus\Vsx2
1 of 14
No
No
Mmus\Zfhx3
1 of 14
No
No
Mmus\Zfhx4
1 of 14
No
No
Xenopus tropicalis (Western clawed frog) (135)
Xtro\alx4
3 of 13
Yes
Yes
Xtro\arx
3 of 13
Yes
No
Xtro\drgx
3 of 13
Yes
No
Xtro\rax2
3 of 13
Yes
No
Xtro\rax
3 of 13
Yes
No
Xtro\crx
2 of 13
No
No
Xtro\gsc2
2 of 13
No
Yes
Xtro\homeobox100496651-provisional
2 of 13
No
Yes
Xtro\LOC100485335
2 of 13
No
No
Xtro\nobox
2 of 13
No
Yes
Xtro\otx2
2 of 13
No
No
Xtro\pax3
2 of 13
No
No
Xtro\phox2b
2 of 13
No
No
Xtro\pitx2
2 of 13
No
No
Xtro\prop1
2 of 13
No
No
Xtro\prrx1
2 of 13
No
No
Xtro\prrx2
2 of 13
No
No
Xtro\shox2
2 of 13
No
No
Xtro\shox
2 of 13
No
No
Xtro\alx1
1 of 13
No
No
Xtro\barhl1
1 of 13
No
No
Xtro\barhl2
1 of 13
No
No
Xtro\barx1
1 of 13
No
No
Xtro\barx2
1 of 13
No
No
Xtro\bsx
1 of 13
No
No
Xtro\cdx1
1 of 13
No
No
Xtro\cdx4
1 of 13
No
No
Xtro\crybb2
1 of 13
No
No
Xtro\cux2
1 of 13
No
No
Xtro\dbx1
1 of 13
No
No
Xtro\dbx2
1 of 13
No
No
Xtro\dlx2
1 of 13
No
No
Xtro\dlx5
1 of 13
No
No
Xtro\dlx6
1 of 13
No
No
Xtro\dmbx1
1 of 13
No
No
Xtro\emx1l
1 of 13
No
No
Xtro\emx1
1 of 13
No
No
Xtro\esx1
1 of 13
No
No
Xtro\evx1
1 of 13
No
No
Xtro\evx2
1 of 13
No
No
Xtro\fkbp4
1 of 13
No
No
Xtro\gbx2.1
1 of 13
No
No
Xtro\gsc
1 of 13
No
No
Xtro\gsx1
1 of 13
No
No
Xtro\hesx1
1 of 13
No
Yes
Xtro\hhex
1 of 13
No
No
Xtro\hlx
1 of 13
No
No
Xtro\hmx1
1 of 13
No
No
Xtro\hmx2
1 of 13
No
No
Xtro\hmx3
1 of 13
No
No
Xtro\hoxa1
1 of 13
No
No
Xtro\hoxa3
1 of 13
No
No
Xtro\hoxa4
1 of 13
No
No
Xtro\hoxa5
1 of 13
No
No
Xtro\hoxa7
1 of 13
No
No
Xtro\hoxa9
1 of 13
No
No
Xtro\hoxb2
1 of 13
No
No
Xtro\hoxb3
1 of 13
No
No
Xtro\hoxb5
1 of 13
No
No
Xtro\hoxb8
1 of 13
No
No
Xtro\hoxc3
1 of 13
No
No
Xtro\hoxc5
1 of 13
No
No
Xtro\hoxc8
1 of 13
No
No
Xtro\hoxc10
1 of 13
No
No
Xtro\hoxc12
1 of 13
No
Yes
Xtro\hoxc13
1 of 13
No
Yes
Xtro\hoxd1
1 of 13
No
No
Xtro\hoxd3
1 of 13
No
No
Xtro\hoxd8
1 of 13
No
No
Xtro\hoxd13
1 of 13
No
Yes
Xtro\isl2
1 of 13
No
No
Xtro\isx
1 of 13
No
Yes
Xtro\lbx1
1 of 13
No
No
Xtro\ldb3
1 of 13
No
No
Xtro\lhx1
1 of 13
No
No
Xtro\lhx5
1 of 13
No
No
Xtro\lhx6
1 of 13
No
No
Xtro\lhx8
1 of 13
No
No
Xtro\lhx9
1 of 13
No
No
Xtro\lmx1a
1 of 13
No
No
Xtro\lmx1b.1
1 of 13
No
No
Xtro\lmx1b.2
1 of 13
No
No
Xtro\LOC100485081
1 of 13
No
No
Xtro\LOC100485697
1 of 13
No
No
Xtro\LOC100487588
1 of 13
No
No
Xtro\LOC100490929
1 of 13
No
No
Xtro\LOC100492873
1 of 13
No
No
Xtro\LOC100493706
1 of 13
No
No
Xtro\LOC100496089
1 of 13
No
No
Xtro\LOC100497614
1 of 13
No
No
Xtro\LOC101731251
1 of 13
No
No
Xtro\LOC101731897
1 of 13
No
No
Xtro\LOC101732809
1 of 13
No
No
Xtro\LOC101734831
1 of 13
No
Yes
Xtro\lpp
1 of 13
No
No
Xtro\med9
1 of 13
No
No
Xtro\meox2
1 of 13
No
No
Xtro\mix1
1 of 13
No
Yes
Xtro\mnx1
1 of 13
No
No
Xtro\msx1
1 of 13
No
No
Xtro\msx2
1 of 13
No
No
Xtro\nkx1-1
1 of 13
No
No
Xtro\nkx2-1
1 of 13
No
No
Xtro\nkx2-3
1 of 13
No
No
Xtro\nkx2-5
1 of 13
No
No
Xtro\nkx2-6
1 of 13
No
No
Xtro\nkx3-3
1 of 13
No
No
Xtro\nkx6-2
1 of 13
No
No
Xtro\nkx6-3
1 of 13
No
No
Xtro\not
1 of 13
No
No
Xtro\otp
1 of 13
No
No
Xtro\pdlim5
1 of 13
No
No
Xtro\pdx1
1 of 13
No
No
Xtro\phox2a
1 of 13
No
No
Xtro\pitx1
1 of 13
No
No
Xtro\pitx3
1 of 13
No
No
Xtro\pou5f3.2
1 of 13
No
No
Xtro\sebox
1 of 13
No
No
Xtro\sia1
1 of 13
No
No
Xtro\sia2
1 of 13
No
Yes
Xtro\sia3
1 of 13
No
Yes
Xtro\six4
1 of 13
No
No
Xtro\tmem143
1 of 13
No
No
Xtro\uncx
1 of 13
No
No
Xtro\ventx1.1
1 of 13
No
No
Xtro\ventx1.2
1 of 13
No
No
Xtro\ventx2.1
1 of 13
No
No
Xtro\ventx2.2
1 of 13
No
No
Xtro\ventx3.2
1 of 13
No
No
Xtro\vmp1
1 of 13
No
No
Xtro\vsx1
1 of 13
No
No
Xtro\vsx2
1 of 13
No
No
Xtro\vtn
1 of 13
No
No
Xtro\zfhx3
1 of 13
No
No
Xtro\zfhx4
1 of 13
No
No
Danio rerio (Zebrafish) (133)
Drer\arxa
4 of 14
Yes
No
Drer\alx1
3 of 14
No
Yes
Drer\alx4a
3 of 14
No
Yes
Drer\alx4b
3 of 14
No
Yes
Drer\arxb
3 of 14
No
No
Drer\drgx
3 of 14
No
No
Drer\phox2a
3 of 14
No
No
Drer\phox2bb
3 of 14
No
No
Drer\rx1
3 of 14
No
No
Drer\rx2
3 of 14
No
No
Drer\rx3
3 of 14
No
No
Drer\alx3
2 of 14
No
Yes
Drer\crx
2 of 14
No
No
Drer\gsc
2 of 14
No
No
Drer\mixl1
2 of 14
No
No
Drer\mxtx1
2 of 14
No
No
Drer\mxtx2
2 of 14
No
No
Drer\otx1
2 of 14
No
No
Drer\otx2a
2 of 14
No
No
Drer\otx2b
2 of 14
No
No
Drer\otx5
2 of 14
No
No
Drer\pax3a
2 of 14
No
No
Drer\pax3b
2 of 14
No
No
Drer\pax7a
2 of 14
No
No
Drer\pax7b
2 of 14
No
No
Drer\pax10
2 of 14
No
No
Drer\phox2ba
2 of 14
No
No
Drer\pitx2
2 of 14
No
No
Drer\prop1
2 of 14
No
No
Drer\prrx1a
2 of 14
No
No
Drer\prrx1b
2 of 14
No
No
Drer\sebox
2 of 14
No
Yes
Drer\shox2
2 of 14
No
No
Drer\shox
2 of 14
No
No
Drer\si:dkey-43p13.5
2 of 14
No
No
Drer\zgc:101100
2 of 14
No
Yes
Drer\barhl1a
1 of 14
No
No
Drer\barhl1b
1 of 14
No
No
Drer\barhl2
1 of 14
No
No
Drer\bsx
1 of 14
No
No
Drer\cdx4
1 of 14
No
No
Drer\dbx1a
1 of 14
No
No
Drer\dbx1b
1 of 14
No
No
Drer\dbx2
1 of 14
No
No
Drer\dharma
1 of 14
No
No
Drer\dlx1a
1 of 14
No
No
Drer\dlx2a
1 of 14
No
No
Drer\dlx2b
1 of 14
No
No
Drer\dlx3b
1 of 14
No
No
Drer\dlx4a
1 of 14
No
No
Drer\dlx4b
1 of 14
No
No
Drer\dlx5a
1 of 14
No
No
Drer\dlx6a
1 of 14
No
No
Drer\dmbx1a
1 of 14
No
No
Drer\dmbx1b
1 of 14
No
No
Drer\emx1
1 of 14
No
No
Drer\emx2
1 of 14
No
No
Drer\eve1
1 of 14
No
No
Drer\evx1
1 of 14
No
No
Drer\gsx1
1 of 14
No
No
1  
Drer\gsx2
1 of 14
No
No
Drer\hhex
1 of 14
No
No
Drer\hlx1
1 of 14
No
No
Drer\hmx1
1 of 14
No
No
Drer\hmx2
1 of 14
No
No
Drer\hmx3a
1 of 14
No
No
Drer\hmx4
1 of 14
No
No
Drer\hoxa1a
1 of 14
No
No
Drer\hoxa2b
1 of 14
No
No
Drer\hoxa3a
1 of 14
No
No
Drer\hoxa4a
1 of 14
No
No
Drer\hoxa11b
1 of 14
No
No
Drer\hoxb1a
1 of 14
No
No
Drer\hoxb1b
1 of 14
No
No
Drer\hoxb2a
1 of 14
No
No
Drer\hoxb3a
1 of 14
No
No
Drer\hoxb4a
1 of 14
No
No
Drer\hoxc3a
1 of 14
No
No
Drer\hoxc11b
1 of 14
No
No
Drer\hoxc12b
1 of 14
No
No
Drer\hoxd3a
1 of 14
No
No
Drer\hoxd11a
1 of 14
No
No
Drer\isl1a
1 of 14
No
No
Drer\isl2a
1 of 14
No
No
Drer\isl2b
1 of 14
No
No
Drer\lbx1a
1 of 14
No
No
Drer\lbx1b
1 of 14
No
No
Drer\lbx2
1 of 14
No
No
Drer\lhx1b
1 of 14
No
No
Drer\lhx2b
1 of 14
No
No
Drer\lhx4
1 of 14
No
No
Drer\lhx9
1 of 14
No
No
Drer\lmx1a
1 of 14
No
No
Drer\LOC100008066
1 of 14
No
No
Drer\meox1
1 of 14
No
No
Drer\meox2a
1 of 14
No
No
Drer\mnx1
1 of 14
No
No
Drer\msx1b
1 of 14
No
No
Drer\msx2a
1 of 14
No
No
Drer\msx2b
1 of 14
No
No
Drer\msx3
1 of 14
No
No
Drer\nkx1.2la
1 of 14
No
No
Drer\nkx2.1
1 of 14
No
No
Drer\nkx2.2b
1 of 14
No
No
Drer\nkx2.4a
1 of 14
No
No
Drer\nkx2.4b
1 of 14
No
No
Drer\nkx2.5
1 of 14
No
No
Drer\nkx2.7
1 of 14
No
No
Drer\nkx3-1
1 of 14
No
No
Drer\nkx3-2
1 of 14
No
No
Drer\nkx6.1
1 of 14
No
No
1  
Drer\nkx6.2
1 of 14
No
No
Drer\nkx6.3
1 of 14
No
No
Drer\noto
1 of 14
No
No
Drer\pax4
1 of 14
No
No
Drer\pax6a
1 of 14
No
No
Drer\pax6b
1 of 14
No
No
Drer\pdx1
1 of 14
No
No
Drer\pitx1
1 of 14
No
No
Drer\pitx3
1 of 14
No
No
Drer\pou5f3
1 of 14
No
No
Drer\six4a
1 of 14
No
No
Drer\six4b
1 of 14
No
No
Drer\six5
1 of 14
No
No
Drer\tlx1
1 of 14
No
No
Drer\tlx3b
1 of 14
No
No
Drer\vax1
1 of 14
No
No
Drer\vax2
1 of 14
No
No
Drer\vsx1
1 of 14
No
No
Drer\vsx2
1 of 14
No
No
Drer\zfhx3a
1 of 14
No
No
Drer\zfhx3b
1 of 14
No
No
Drer\zfhx4
1 of 14
No
No
Caenorhabditis elegans (Nematode, roundworm) (60)
Cele\alr-1
4 of 14
Yes
No
Cele\ceh-8
4 of 14
Yes
No
Cele\ceh-10
2 of 14
No
No
Cele\ceh-17
2 of 14
No
No
Cele\ceh-37
2 of 14
No
No
Cele\ceh-45
2 of 14
No
No
Cele\ceh-53
2 of 14
No
No
Cele\ceh-54
2 of 14
No
No
Cele\dsc-1
2 of 14
No
Yes
Cele\eyg-1
2 of 14
No
No
Cele\ttx-1
2 of 14
No
No
Cele\unc-4
2 of 14
No
No
Cele\unc-30
2 of 14
No
No
Cele\unc-42
2 of 14
No
No
Cele\ceh-1
1 of 14
No
No
Cele\ceh-2
1 of 14
No
No
Cele\ceh-7
1 of 14
No
No
Cele\ceh-9
1 of 14
No
No
Cele\ceh-14
1 of 14
No
No
Cele\ceh-16
1 of 14
No
No
Cele\ceh-19
1 of 14
No
No
Cele\ceh-23
1 of 14
No
No
Cele\ceh-24
1 of 14
No
No
Cele\ceh-27
1 of 14
No
No
Cele\ceh-28
1 of 14
No
No
Cele\ceh-30
1 of 14
No
No
Cele\ceh-31
1 of 14
No
No
Cele\ceh-34
1 of 14
No
No
Cele\ceh-36
1 of 14
No
No
Cele\ceh-43
1 of 14
No
No
Cele\ceh-44
1 of 14
No
No
Cele\ceh-51
1 of 14
No
No
Cele\ceh-58
1 of 14
No
Yes
Cele\ceh-62
1 of 14
No
No
Cele\ceh-87
1 of 14
No
Yes
Cele\cog-1
1 of 14
No
No
Cele\duxl-1
1 of 14
No
Yes
Cele\egl-5
1 of 14
No
No
Cele\lim-4
1 of 14
No
No
Cele\lim-6
1 of 14
No
No
Cele\lin-11
1 of 14
No
No
Cele\lin-39
1 of 14
No
No
Cele\mab-5
1 of 14
No
No
Cele\mec-3
1 of 14
No
No
Cele\mls-2
1 of 14
No
No
Cele\nob-1
1 of 14
No
No
Cele\npax-1
1 of 14
No
No
Cele\npax-2
1 of 14
No
No
Cele\npax-3
1 of 14
No
No
Cele\npax-4
1 of 14
No
No
Cele\pax-3
1 of 14
No
No
Cele\pha-2
1 of 14
No
No
Cele\php-3
1 of 14
No
No
Cele\pxl-1
1 of 14
No
No
Cele\tab-1
1 of 14
No
No
Cele\ttx-3
1 of 14
No
No
Cele\vab-3
1 of 14
No
No
Cele\vab-7
1 of 14
No
No
1  
Cele\vab-15
1 of 14
No
No
Cele\zag-1
1 of 14
No
No
Anopheles gambiae (African malaria mosquito) (74)
Agam\AgaP_AGAP007985
5 of 12
Yes
No
Agam\AgaP_AGAP000858
4 of 12
No
Yes
Agam\AgaP_AGAP001483
3 of 12
No
No
Agam\AgaP_AGAP005311
3 of 12
No
No
Agam\AgaP_AGAP000190
2 of 12
No
No
Agam\AgaP_AGAP000215
2 of 12
No
No
Agam\AgaP_AGAP001593
2 of 12
No
No
Agam\AgaP_AGAP002487
2 of 12
No
No
Agam\AgaP_AGAP005096
2 of 12
No
No
Agam\AgaP_AGAP008868
2 of 12
No
No
Agam\AgaP_AGAP010358
2 of 12
No
No
Agam\AgaP_AGAP010359
2 of 12
No
No
Agam\AgaP_AGAP011417
2 of 12
No
No
Agam\AgaP_AGAP012303
2 of 12
No
No
Agam\AgaP_AGAP012501
2 of 12
No
No
Agam\ABDA_ANOGA
1 of 12
No
No
Agam\AgaP_AGAP000057
1 of 12
No
No
Agam\AgaP_AGAP000063
1 of 12
No
No
Agam\AgaP_AGAP000067
1 of 12
No
No
Agam\AgaP_AGAP000484
1 of 12
No
No
Agam\AgaP_AGAP000731
1 of 12
No
No
Agam\AgaP_AGAP001389
1 of 12
No
No
Agam\AgaP_AGAP001493
1 of 12
No
No
Agam\AgaP_AGAP001495
1 of 12
No
No
Agam\AgaP_AGAP001560
1 of 12
No
No
Agam\AgaP_AGAP001618
1 of 12
No
No
Agam\AgaP_AGAP001619
1 of 12
No
No
Agam\AgaP_AGAP002372
1 of 12
No
No
Agam\AgaP_AGAP002431
1 of 12
No
No
Agam\AgaP_AGAP003669
1 of 12
No
No
Agam\AgaP_AGAP003670
1 of 12
No
No
Agam\AgaP_AGAP003671
1 of 12
No
No
Agam\AgaP_AGAP003672
1 of 12
No
No
Agam\AgaP_AGAP003674
1 of 12
No
No
Agam\AgaP_AGAP004548
1 of 12
No
No
Agam\AgaP_AGAP004646
1 of 12
No
No
Agam\AgaP_AGAP004648
1 of 12
No
No
Agam\AgaP_AGAP004649
1 of 12
No
No
Agam\AgaP_AGAP004660
1 of 12
No
No
Agam\AgaP_AGAP004661
1 of 12
No
No
Agam\AgaP_AGAP005011
1 of 12
No
No
Agam\AgaP_AGAP005041
1 of 12
No
No
Agam\AgaP_AGAP005099
1 of 12
No
No
Agam\AgaP_AGAP005137
1 of 12
No
No
Agam\AgaP_AGAP005138
1 of 12
No
No
Agam\AgaP_AGAP005281
1 of 12
No
No
Agam\AgaP_AGAP005346
1 of 12
No
No
Agam\AgaP_AGAP005425
1 of 12
No
No
Agam\AgaP_AGAP005727
1 of 12
No
No
Agam\AgaP_AGAP006536
1 of 12
No
No
Agam\AgaP_AGAP006537
1 of 12
No
No
Agam\AgaP_AGAP006540
1 of 12
No
No
Agam\AgaP_AGAP006923
1 of 12
No
No
Agam\AgaP_AGAP007058
1 of 12
No
No
Agam\AgaP_AGAP008980
1 of 12
No
No
Agam\AgaP_AGAP009088
1 of 12
No
No
Agam\AgaP_AGAP009293
1 of 12
No
No
Agam\AgaP_AGAP009294
1 of 12
No
No
Agam\AgaP_AGAP009503
1 of 12
No
No
Agam\AgaP_AGAP009646
1 of 12
No
No
Agam\AgaP_AGAP010209
1 of 12
No
No
Agam\AgaP_AGAP010279
1 of 12
No
No
Agam\AgaP_AGAP010391
1 of 12
No
No
Agam\AgaP_AGAP011134
1 of 12
No
No
Agam\AgaP_AGAP011143
1 of 12
No
No
Agam\AgaP_AGAP011253
1 of 12
No
No
Agam\AgaP_AGAP011695
1 of 12
No
No
Agam\AgaP_AGAP012001
1 of 12
No
No
Agam\AgaP_AGAP012428
1 of 12
No
No
Agam\AgaP_AGAP013157
1 of 12
No
No
Agam\AgaP_AGAP013373
1 of 12
No
No
Agam\EXD_ANOGA
1 of 12
No
No
Agam\HMEN_ANOGA
1 of 12
No
No
Agam\PRIC1_ANOGA
1 of 12
No
No
Arabidopsis thaliana (thale-cress) (46)
Atha\HB-1
2 of 13
Yes
Yes
Atha\HB21
2 of 13
Yes
No
Atha\HB40
2 of 13
Yes
No
Atha\HB53
2 of 13
Yes
No
Atha\HDG7
2 of 13
Yes
Yes
Atha\RLT2
2 of 13
Yes
Yes
Atha\ANL2
1 of 13
No
No
Atha\AT4G03090
1 of 13
No
Yes
Atha\ATHB13
1 of 13
No
No
Atha\AtHB23
1 of 13
No
No
Atha\ATHB54
1 of 13
No
No
Atha\FWA
1 of 13
No
No
Atha\GL2
1 of 13
No
No
Atha\HAT1
1 of 13
No
No
Atha\HAT2
1 of 13
No
No
Atha\HAT3
1 of 13
No
No
Atha\HAT9
1 of 13
No
No
Atha\HAT14
1 of 13
No
No
Atha\HAT22
1 of 13
No
No
Atha\HB-1
1 of 13
No
No
Atha\HB-2
1 of 13
No
No
Atha\HB-3
1 of 13
No
No
Atha\HB4
1 of 13
No
No
Atha\HB5
1 of 13
No
No
Atha\HB6
1 of 13
No
No
Atha\HB-7
1 of 13
No
No
Atha\HB-7
1 of 13
No
No
Atha\HB-8
1 of 13
No
No
Atha\HB16
1 of 13
No
No
Atha\HB17
1 of 13
No
No
Atha\HB18
1 of 13
No
No
Atha\HB20
1 of 13
No
No
Atha\HB22
1 of 13
No
No
Atha\HB51
1 of 13
No
No
Atha\HDG1
1 of 13
No
No
Atha\HDG2
1 of 13
No
No
Atha\HDG4
1 of 13
No
No
Atha\HDG8
1 of 13
No
Yes
Atha\HDG9
1 of 13
No
No
Atha\HDG11
1 of 13
No
No
Atha\PDF2
1 of 13
No
No
Atha\PHV
1 of 13
No
No
Atha\REV
1 of 13
No
No
Atha\WOX10
1 of 13
No
Yes
Atha\WOX13
1 of 13
No
Yes
Atha\WOX14
1 of 13
No
Yes
Saccharomyces cerevisiae (Brewer's yeast) (3)
Scer\PHO2
3 of 13
Yes
Yes
Scer\YHP1
3 of 13
Yes
Yes
Scer\YOX1
2 of 13
No
No
Schizosaccharomyces pombe (Fission yeast) (1)
Spom\phx1
3 of 12
Yes
No
Escherichia coli (enterobacterium) (0)
Other Organism Orthologs (via OrthoDB)
Data provided directly from OrthoDB:Pph13. Refer to their site for version information.
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v9.1)
Gene Symbol
Score
Source
Compara
Domainoid
eggNOG
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Drosophila melanogaster (Fruit fly) (93)
al
7 of 13
CG9876
5 of 13
CG11294
5 of 13
CG32532
5 of 13
Drgx
5 of 13
Gsc
5 of 13
hbn
5 of 13
repo
5 of 13
Rx
5 of 13
ey
4 of 13
eyg
4 of 13
gsb
4 of 13
gsb-n
4 of 13
oc
4 of 13
prd
4 of 13
Ptx1
4 of 13
toe
4 of 13
Vsx2
4 of 13
CG34367
3 of 13
eve
3 of 13
otp
3 of 13
PHDP
3 of 13
unc-4
3 of 13
Vsx1
3 of 13
abd-A
2 of 13
Antp
2 of 13
ap
2 of 13
Awh
2 of 13
bap
2 of 13
B-H1
2 of 13
B-H2
2 of 13
bsh
2 of 13
C15
2 of 13
cad
2 of 13
CG4328
2 of 13
CG18599
2 of 13
CG34031
2 of 13
Dbx
2 of 13
Dll
2 of 13
Dr
2 of 13
E5
2 of 13
ems
2 of 13
en
2 of 13
exex
2 of 13
ftz
2 of 13
HGTX
2 of 13
HHEX
2 of 13
Hmx
2 of 13
ind
2 of 13
lbe
2 of 13
lbl
2 of 13
Lim1
2 of 13
Lim3
2 of 13
lms
2 of 13
Lmx1a
2 of 13
NK7.1
2 of 13
OdsH
2 of 13
ro
2 of 13
Scr
2 of 13
sv
2 of 13
toy
2 of 13
tup
2 of 13
Ubx
2 of 13
unpg
2 of 13
vnd
2 of 13
zen2
2 of 13
zen
2 of 13
zfh1
2 of 13
zfh2
2 of 13
Abd-B
1 of 13
bcd
1 of 13
btn
1 of 13
Bx
1 of 13
CG5708
1 of 13
CG11085
1 of 13
CG15696
1 of 13
Dfd
1 of 13
H2.0
1 of 13
inv
1 of 13
jub
1 of 13
lab
1 of 13
LIMK1
1 of 13
mirr
1 of 13
pb
1 of 13
pk
1 of 13
Poxm
1 of 13
Poxn
1 of 13
Six4
1 of 13
slou
1 of 13
tin
1 of 13
Unc-115a
1 of 13
Unc-115b
1 of 13
Zyx
1 of 13
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 10 )
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    ALX1; ALX homeobox 1
    5 of 14
    601527
    ALX3; ALX homeobox 3
    5 of 14
    606014
    ALX4; ALX homeobox 4
    5 of 14
    605420
    ARX; aristaless related homeobox
    5 of 14
    300382
    DRGX; dorsal root ganglia homeobox
    3 of 14
    606701
        ISX; intestine specific homeobox
        3 of 14
        612019
            RAX2; retina and anterior neural fold homeobox 2
            3 of 14
            610362
            RAX; retina and anterior neural fold homeobox
            3 of 14
            601881
             
            Functional Complementation Data
            Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
            Interactions
            Summary of Physical Interactions
            Summary of Genetic Interactions
            Interaction Browsers
            View in FlyBase Interactions Browser   View in MIST tool (external link)
            Please look at the allele data for full details of the genetic interactions
            Starting gene(s)
            Interaction type
            Interacting gene(s)
            Reference
            Pph13
            enhanceable
            oc
            (Mishra et al., 2010)
            Starting gene(s)
            Interaction type
            Interacting gene(s)
            Reference
            gl
            suppressible
            Pph13
            (Liang et al., 2016)
            oc
            enhanceable
            Pph13
            (Mishra et al., 2010)
            External Data
            Linkouts
            DroID - A comprehensive database of gene and protein interactions.
            Pathways
            Signaling Pathways (FlyBase)
            Metabolic Pathways
            FlyBase
            External Links
            External Data
            Linkouts
            Class of Gene
            Genomic Location and Detailed Mapping Data
            Chromosome (arm)
            2L
            Recombination map
            2-1.5
            Cytogenetic map
            21E2-21E2
            Sequence location
            FlyBase Computed Cytological Location
            Cytogenetic map
            Evidence for location
            21E2-21E2
            Limits computationally determined from genome sequence between P{lacW}l(2)k09610k09610&P{lacW}Sk09538a and P{PZ}l(2)1068510685&P{lacW}Tango14k00619
            Experimentally Determined Cytological Location
            Cytogenetic map
            Notes
            References
            21C-21D
            (Goriely, 1999.4.29)
            21C5-21C6
            (Goriely et al., 1999)
            21C5-21C6
            (determined by in situ hybridisation)
            (Goriely, 1996.8.22)
            21C1-21D2
            (Schneitz and Noll, 1990)
            Gsc and Pph13 map within 10kb of each other. The cytological location has been previously, and erroneously, reported as 60C (FBrf0065373).
            (Goriely, 1996.8.22)
            Experimentally Determined Recombination Data
            Location

            2-1.5

            (FlyBase, 2016)

            2-0.2

            (Comeron et al., 2012)

            2-

            Left of (cM)
            Right of (cM)
            Notes
            Stocks and Reagents
            Stocks (14)
            Genomic Clones (10)
             

            Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

            cDNA Clones (5)
             

            Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

            cDNA clones, fully sequenced
            BDGP DGC clones
            Other clones
            Drosophila Genomics Resource Center cDNA clones

            For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

            cDNA Clones, End Sequenced (ESTs)
            BDGP DGC clones
            Other clones
            RNAi and Array Information
            Linkouts
            DRSC - Results frm RNAi screens
            Antibody Information
            Laboratory Generated Antibodies
             

            polyclonal

            (Zelhof et al., 2003)
            Commercially Available Antibodies
             
            Cell Line Information
            Publicly Available Cell Lines
             
              Other Stable Cell Lines
               
                Other Comments

                The sequence used to clone Gsc as reported in FBrf0087230 was '60Mun2', not Pph13 (60Mun1).

                (Noll and McGinnis, 1998.2.19)

                Pph13 is a prd-type homeobox gene.

                (Schneitz and Noll, 1990)

                An incompletely characterised homeodomain sequence.

                Relationship to Other Genes
                Source for database merge of
                Additional comments

                Pph13 and Gsc are closely linked.

                (Schneitz and Noll, 1990)
                Nomenclature History
                Source for database identify of

                Source for identity of: Pph13 CG2819

                (Guan, 1999.11)
                Nomenclature comments
                Etymology

                The gene is named "hazy" based on the malformed rhabdomeres seen in the mutant and the inability of the mutant to detect light.

                (Zelhof et al., 2003)
                Synonyms and Secondary IDs (9)
                Datasets (0)
                Study focus (0)
                Experimental Role
                Project
                Project Type
                Title
                Study result (0)
                Result
                Result Type
                Title
                External Crossreferences and Linkouts ( 40 )
                Sequence Crossreferences
                NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
                GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
                GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
                RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
                UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.
                UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
                Other crossreferences
                AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.
                BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
                DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
                EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
                FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
                FlyMine - An integrated database for Drosophila genomics
                InterPro - A database of protein families, domains and functional sites
                KEGG Genes - Molecular building blocks of life in the genomic space.
                MARRVEL_MODEL - MARRVEL (model organism gene)
                Linkouts
                Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
                DroID - A comprehensive database of gene and protein interactions.
                DRSC - Results frm RNAi screens
                Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
                FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
                FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
                Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
                Flygut - An atlas of the Drosophila adult midgut
                iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
                Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
                References (77)