FlyBase Gene Report: Dmel\OdsH

General Information

Symbol

Dmel\OdsH

Species

D. melanogaster

Name

Ods-site homeobox

Annotation Symbol

CG6352

Feature Type

protein_coding_gene

FlyBase ID

FBgn0026058

Gene Model Status

Current

Stock Availability

56 publicly available

Gene Summary

Ods-site homeobox (OdsH) encodes a protein involved in male sterility. [Date last reviewed: 2019-03-14] (FlyBase Gene Snapshot)

All Summaries

Gene Snapshot
Alliance
Auto summary
Gene Group
Interactive Fly

Key Links

Genomic Location

Cytogenetic map

16D1-16D3

Sequence location

X:17,791,010..17,814,011 [+]

Recombination map

1-58

RefSeq locus

NC_004354 REGION:17791010..17814011

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (7 terms)

Molecular Function (3 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (3 terms)

CV Term

Evidence

References

enables DNA binding

inferred from electronic annotation with InterPro:IPR001356

(InterPro Project Members, 2004-)

enables DNA-binding transcription factor activity, RNA polymerase II-specific

inferred from electronic annotation with InterPro:IPR017970

(InterPro Project Members, 2004-)

enables sequence-specific double-stranded DNA binding

inferred from biological aspect of ancestor with PANTHER:PTN001551498

(GO Reference Genome Project, 2011-)

Biological Process (3 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

involved_in insemination

inferred from high throughput expression pattern

(Findlay et al., 2008)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

involved_in regulation of DNA-templated transcription

inferred from electronic annotation with InterPro:IPR017970

(InterPro Project Members, 2004-)

involved_in regulation of gene expression

inferred from biological aspect of ancestor with PANTHER:PTN001551498

(GO Reference Genome Project, 2011-)

Cellular Component (1 term)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

located_in extracellular space

inferred from high throughput direct assay

(Findlay et al., 2008)

Terms Based on Predictions or Assertions (0 terms)

Gene Group (FlyBase)

PAIRED-LIKE HOMEOBOX TRANSCRIPTION FACTORS

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Gene Snapshot

Ods-site homeobox (OdsH) encodes a protein involved in male sterility. [Date last reviewed: 2019-03-14]

Gene Group (FlyBase)

PAIRED-LIKE HOMEOBOX TRANSCRIPTION FACTORS -: Paired-like (PRD-like) homeobox transcription factors are sequence-specific DNA binding proteins that regulate transcription. PRD-like transcription factors lack a paired domain but possess a homeodomain characteristic of the paired homeobox transcription factors. Some members also possess an Engrailed Homology 1 (EH1) and/or an OAR motif near the C-terminus. (Adapted from FBrf0232555 and FBrf0106517).

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\OdsH for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry Q9VX20)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Gene model reviewed during 5.51

Low-frequency RNA-Seq exon junction(s) not annotated.

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

OdsH-RA

FBtr0074461

NM_078665

1289

382

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

OdsH-PA

FBpp0074235

42.7

382

6.65

Q9VX20

NP_523389

AAF48763

Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\OdsH using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

OdsH_1

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

3.42

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 11 -- 12

hypopharynx proper primordium

(Fisher et al., 2012)

embryonic stage 13 -- 16

embryonic hypopharynx

(Fisher et al., 2012)

embryonic ventral epidermis

(Fisher et al., 2012)

larval labral sensory complex

(Fisher et al., 2012)

ventral sensory complex primordium

(Fisher et al., 2012)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

located_in extracellular space

inferred from high throughput direct assay

(Findlay et al., 2008)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\OdsH in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\OdsH

View exonic expression by tissue for Dmel\OdsH

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0026058

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

32758/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0026058

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0026058

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0026058

Flygut - An atlas of the Drosophila adult midgut

FBgn0026058

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 2 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 9 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of OdsH

Transgenic constructs containing regulatory region of OdsH

Aberrations (Deficiencies and Duplications) ( 0 )

Inferred from experimentation ( 0 )

Inferred from location ( 10 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

viable

OdsH⁰

viable, with Scer\GAL4^tin.CΔ4

OdsH^GD4380

Sterility

Allele

male semi-fertile

OdsH⁰

male semi-sterile

OdsH⁰

Other Phenotypes

Allele

visible, with Scer\GAL4^Bx-MS1096

OdsH^{UAS.ORF.GW.Tag:HA}

visible | cold sensitive, with Scer\GAL4^Bx-MS1096

OdsH^{UAS.ORF.GW.Tag:HA}

Phenotype manifest in

Allele

male germline stem cell

OdsH⁰

primary gonial cell

OdsH⁰

spermatogonium

OdsH⁰

wing, with Scer\GAL4^Bx-MS1096

OdsH^{UAS.ORF.GW.Tag:HA}

wing | cold sensitive, with Scer\GAL4^Bx-MS1096

OdsH^{UAS.ORF.GW.Tag:HA}

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (152)

Hsap\UNCX

7 of 14

Yes

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Hsap\DUX3

1 of 14

Yes

Hsap\DUX4

1 of 14

Hsap\DUX4L4

1 of 14

Yes

Hsap\DUX4L7

1 of 14

Yes

Hsap\DUX4L9

1 of 14

Yes

Hsap\DUX5

1 of 14

Yes

Hsap\DUXA

1 of 14

Yes

Hsap\DUXB

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

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1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (94)

Rnor\Uncx

8 of 14

Yes

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Rnor\LOC691325

1 of 14

Rnor\LOC100361016

1 of 14

Yes

Rnor\LOC100364002

1 of 14

Rnor\LOC102553890

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Rnor\Rax

1 of 14

Rnor\Rhox3

1 of 14

Yes

Rnor\Rhox4g

1 of 14

Yes

Rnor\Rhox8

1 of 14

Rnor\Rhox9

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

Mus musculus (laboratory mouse) (123)

Mmus\Uncx

6 of 14

Yes

2 of 14

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Mmus\Obox3

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Mmus\Rhox2b

1 of 14

Yes

Mmus\Rhox2e

1 of 14

Yes

Mmus\Rhox2f

1 of 14

Yes

Mmus\Rhox2g

1 of 14

Yes

Mmus\Rhox3a2

1 of 14

Yes

Mmus\Rhox3a

1 of 14

Yes

Mmus\Rhox3c

1 of 14

Yes

Mmus\Rhox3e

1 of 14

Yes

Mmus\Rhox3f

1 of 14

Yes

Mmus\Rhox3g

1 of 14

Yes

Mmus\Rhox3h

1 of 14

Yes

Mmus\Rhox4a2

1 of 14

Yes

Mmus\Rhox4a

1 of 14

Yes

Mmus\Rhox4c

1 of 14

Yes

Mmus\Rhox4e

1 of 14

Yes

Mmus\Rhox4f

1 of 14

Yes

Mmus\Rhox4g

1 of 14

Yes

Mmus\Rhox6

1 of 14

Yes

Mmus\Rhox7a

1 of 14

Yes

Mmus\Rhox7b

1 of 14

Yes

Mmus\Rhox8

1 of 14

Yes

Mmus\Rhox9

1 of 14

Yes

Mmus\Rhox10

1 of 14

Mmus\Rhox11

1 of 14

Mmus\Rhox12

1 of 14

Yes

Mmus\Rhox13

1 of 14

Mmus\Sebox

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

Xenopus tropicalis (Western clawed frog) (117)

Xtro\uncx

6 of 13

Yes

Xtro\gsc2

2 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Xtro\hoxc13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Danio rerio (Zebrafish) (136)

Drer\uncx

6 of 14

Yes

Drer\uncx4.1

5 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

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1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Caenorhabditis elegans (Nematode, roundworm) (50)

Cele\unc-4

5 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Anopheles gambiae (African malaria mosquito) (63)

Agam\AgaP_AGAP001495

4 of 12

Yes

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

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1 of 12

1 of 12

1 of 12

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1 of 12

1 of 12

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1 of 12

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1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Arabidopsis thaliana (thale-cress) (26)

Atha\HB-1

2 of 13

Yes

Atha\HB21

2 of 13

Yes

Atha\HB40

2 of 13

Yes

Atha\HDG1

2 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Atha\HDG9

1 of 13

Atha\PDF2

1 of 13

Atha\RLT2

1 of 13

Saccharomyces cerevisiae (Brewer's yeast) (3)

Scer\YOX1

2 of 13

Yes

Scer\PHO2

1 of 13

Scer\YHP1

1 of 13

Schizosaccharomyces pombe (Fission yeast) (2)

Spom\phx1

1 of 12

Yes

Spom\yox1

1 of 12

Yes

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:OdsH. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (78)

8 of 13

2 of 13

2 of 13

2 of 13

2 of 13

btn

2 of 13

cad

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

Dfd

2 of 13

Drgx

2 of 13

ems

2 of 13

eve

2 of 13

exex

2 of 13

eyg

2 of 13

ftz

2 of 13

gsb

2 of 13

gsb-n

2 of 13

Gsc

2 of 13

hbn

2 of 13

HGTX

2 of 13

ind

2 of 13

lms

2 of 13

otp

2 of 13

PHDP

2 of 13

Pph13

2 of 13

prd

2 of 13

Ptx1

2 of 13

repo

2 of 13

Scr

2 of 13

tin

2 of 13

toe

2 of 13

toy

2 of 13

Ubx

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

zen

2 of 13

Abd-B

1 of 13

bap

1 of 13

bcd

1 of 13

bsh

1 of 13

C15

1 of 13

CG11085

1 of 13

CG18599

1 of 13

Dbx

1 of 13

Dll

1 of 13

exd

1 of 13

H2.0

1 of 13

HHEX

1 of 13

Hmx

1 of 13

inv

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lab

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lbe

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lbl

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tup

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vnd

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Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

UNCX; UNC homeobox

7 of 14

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

OdsH - CG11906

two hybrid array

(Shokri et al., 2019)

OdsH - CG5446

anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based

(Rhee et al., 2014)

OdsH - Hsp23

anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based

(Rhee et al., 2014)

OdsH - Hsp26

anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based

(Rhee et al., 2014)

OdsH - Su(H)

two hybrid array

(Shokri et al., 2019)

OdsH - chn

two hybrid array

(Shokri et al., 2019)

OdsH - sens-2

two hybrid array

(Shokri et al., 2019)

Summary of Genetic Interactions

Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0026058

MIST (protein-protein) - An integrated Molecular Interaction Database

32758

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

Class of Gene

nuclear_gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

1-58

Cytogenetic map

16D1-16D3

Sequence location

X:17,791,010..17,814,011 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

16D1-16D3

Limits computationally determined from genome sequence between P{EP}EP1464 and P{EP}EP970

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

16D-16D

(Ting, 1998.9.28)

Experimentally Determined Recombination Data

Location

1-58

(FlyBase, 2016)

1-58.5

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (56)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

50046

w¹¹¹⁸; P{GMR39D07-GAL4}attP2

50048

w¹¹¹⁸; P{GMR39E01-GAL4}attP2

50125

w¹¹¹⁸; P{GMR41E01-GAL4}attP2

50148

w¹¹¹⁸; P{GMR42C03-GAL4}attP2

52776

w¹¹¹⁸; P{GMR39E01-lexA}attP40

53637

w¹¹¹⁸; P{GMR39D07-lexA}attP40

70199

w¹¹¹⁸; P{R41E01-p65.AD}attP40

FlyORF

F000261

M{UAS-OdsH.ORF.3xHA.GW}ZH-86Fb

Korea

16319

PBac{GMR39E01-lexA}VK00022

16312

P{GMR39E01-lexA}su(Hw)attP5

VDRC

v103949

P{KK102919}VIE-260B

v51288

w¹¹¹⁸; P{GD4380}v51288

More stocks available...

Genomic Clones (23)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (2)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

IP01524

Other clones

DPiM_IP01524

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0026058

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0026058

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

Mutant males show a subtle defect in fertility. Under normal conditions, no defect is seen, but under sperm-exhaustion conditions, young male adults (2-3 days old) show a reduction in fertility compared to control males.

(Sun et al., 2004)

Relationship to Other Genes

Source for database merge of

Additional comments

Nomenclature History

Source for database identify of

Nomenclature comments

A D.melanogaster transcription unit (OdsH) has been isolated which maps to the location of the Dmau\OdsH or Dsim\OdsH locus defined by introgression of D.mauritiana sequences into D.simulans. This transcript has been named OdsH to imply the correspondence in position between the genetic and molecular data without stating their functional equivalence. OdsH is also present in D.mauritiana (Dmau\OdsH) and D.simulans (Dsim\OdsH).

(Ting et al., 1998)

Etymology

Synonyms and Secondary IDs (7)

Reported As

Symbol Synonym

CG6352

(Ni et al., 2011.7.19, Keleman et al., 2009.8.5, Perkins et al., 2009, Franchini et al., 2004)

OdsH^mel

(Chen and Ting, 2005)

Odsh

(Peng et al., 2016)

odsH

(Kind et al., 2008)

odsh

(Andersen et al., 2010)

Name Synonyms

Ods-site homeobox

(Van Bortle et al., 2012, Ting et al., 1998)

Secondary FlyBase IDs

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 29 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

32758

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

AF095575

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

Q9VX20

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

Q9VX20

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0026058

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

32758/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0026058

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0026058

FlyMine - An integrated database for Drosophila genomics

FBgn0026058

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG6352

MARRVEL_MODEL - MARRVEL (model organism gene)

32758

Linkouts

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0026058

DroID - A comprehensive database of gene and protein interactions.

FBgn0026058

DRSC - Results frm RNAi screens

FBgn0026058

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

OdsH_1

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0026058

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0026058

Flygut - An atlas of the Drosophila adult midgut

FBgn0026058

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC005661

MIST (protein-protein) - An integrated Molecular Interaction Database

32758

References (68)

The following external sites may use different assemblies or annotations than FlyBase.

3.42

Report Sections