FB2026_02 , released June 18, 2026
Allele: Dmel\Act5C2458
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General Information
Symbol
Dmel\Act5C2458
Species
D. melanogaster
Name
FlyBase ID
FBal0188268
Feature type
allele
Associated gene
Dmel\Act5C
Associated Insertion(s)
P{lArB}Act5C2458
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Wagner et al., 2002)
Progenitor genotype
Associated Insertion(s)
P{lArB}Act5C2458
Cytology
Description

P{lArB} insertion within a 200bp region approximately 3kb upstream of the Act5C transcriptional start.

(Wagner et al., 2002)
Allele components
Component
Use(s)
Inserted element
P{lArB}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Act5C2458 homozygotes die as first instar larvae. Shortly after hatching the mutant larvae are indistinguishable from wild type with regards to movement, but they soon appear noticeably sluggish and die within 4 days after egg hatching without growing substantially or molting.

      (Wagner et al., 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Act5C2458
      Name Synonyms
      Secondary FlyBase IDs
        References (1)