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General Information
Symbol
Dmel\Dscam1UAS.cWa
Species
D. melanogaster
Name
FlyBase ID
FBal0189628
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of Dscam1.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

When DscamScer\UAS.cWa is driven in the midline by Scer\GAL4sim.PS, neither the morphology of the midline cells nor guidance of the interneurons across it are disrupted. When DscamScer\UAS.cWa is driven in the interneurons by Scer\GAL4eg-Mz360, in about 59% of the segments, posterior commissure (PC) interneurons do not cross the midline. These axons are often visible as short stumps, or as longer processes that invade the midline but fail to fasciculate with axons of PC interneurons from the contralateral side. The arrangement of PC cell bodies is also abnormal, rather than forming a tight cluster they remain loosely associated or in some cases completely separate from one another. When DscamScer\UAS.cWa is driven in both the interneurons and the midline by Scer\GAL4eg-Mz360 and Scer\GAL4sim.PS, only 3.5% of the PC axons cross the midline. The anterior commissure interneurons are not affected.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Dscam1Scer\UAS.cWa
Dscam1UAS.cWa
DscamScer\UAS.cWa
Name Synonyms
Secondary FlyBase IDs
    References (2)