FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\crbT6AT9AS11AS13A.intra.UAS
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General Information
Symbol
Dmel\crbT6AT9AS11AS13A.intra.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0189972
Feature type
allele
Associated gene
Dmel\crb
Associated Insertion(s)
Carried in Construct
P{UAS-crb.intra.T6AT9AS11AS13A}
Key Links
Transgenic product class
inframe_deletion
(Sotillos et al., 2004)
missense_variant
(Sotillos et al., 2004)
polypeptide_post_translational_processing_variant
(Sotillos et al., 2004)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Sotillos et al., 2004)
missense_variant
(Sotillos et al., 2004)
polypeptide_post_translational_processing_variant
(Sotillos et al., 2004)
Mutagen
in vitro construct
(Sotillos et al., 2004)
Progenitor genotype
Carried in construct
P{UAS-crb.intra.T6AT9AS11AS13A}
Cytology
Description

A mutated, non-phosphorylatable form of the intracellular crb section, is ligated with the signal peptide and transmembrane domain of crb. Carries the amino acid replacements T6A, T9A, S11A and S13A.

(Sotillos et al., 2004)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
crb
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of crbT6AT9AS11AS13A.intra.Scer\UAS under the control of Scer\GAL4ems.HRE results in variable degrees of spiracle shortening in embryos.

      (Lovegrove et al., 2006)

      Overexpression of nonphosphorylatable crbT6AT9AS11AS13A.intra.Scer\UAS, under the regulation of Scer\GAL4en-e16E generally leads to embryonic lethality, in a few cases, surviving flies are obtained and display only mild defects in the posterior crossvein.

      (Sotillos et al., 2004)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      crbT6AT9AS11AS13A.intra.Scer\UAS
      crbT6AT9AS11AS13A.intra.UAS
      crbDN
      (Lovegrove et al., 2006)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)