FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\nodNDD4.UASp.EGFP
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General Information
Symbol
Dmel\nodNDD4.UASp.EGFP
Species
D. melanogaster
Name
FlyBase ID
FBal0190284
Feature type
allele
Associated gene
Dmel\nod
Associated Insertion(s)
Carried in Construct
P{UASp-nod-EGFP.NDD4}
Key Links
Transgenic product class
missense_variant
(Cui and Hawley, 2005)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Cui and Hawley, 2005)
Mutagen
in vitro construct
(Cui and Hawley, 2005)
Progenitor genotype
Carried in construct
P{UASp-nod-EGFP.NDD4}
Cytology
Description

UASp regulatory sequences drive expression of a mutated form of nod (carries the amino acid replacement L635A). The protein is tagged at the C-terminal end with EGFP.

(Cui and Hawley, 2005)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
nod
Tagged with
EGFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of nodNDD4.Scer\UAS.P\T.T:Avic\GFP-EGFP under the control of Scer\GAL4nos.UTR.T:Hsim\VP16 in an In(1)FM7 nod+ background does not cause an increase in meiotic nondisjunction of the X and 4th chromosomes.

      (Cui and Hawley, 2005)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Scer\GAL4VP16.nanos.UTR/nodNDD4.UASp.EGFP partially rescues nod4/noda

      (Cui and Hawley, 2005)
      Comments

      Expression of nodNDD4.Scer\UAS.P\T.T:Avic\GFP-EGFP under the control of Scer\GAL4nos.UTR.T:Hsim\VP16 partially rescues the meiotic defects (high levels of X and 4th chromosome nondisjunction) seen in In(1)FM7 nod4/noda females.

      (Cui and Hawley, 2005)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      nodNDD4.Scer\UAS.P\T.T:Avic\GFP-EGFP
      nodNDD4.UASp.EGFP
      Name Synonyms
      Secondary FlyBase IDs
        References (1)