FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\DuoxΔPHD.UAS
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General Information
Symbol
Dmel\DuoxΔPHD.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0191230
Feature type
allele
Associated gene
Dmel\Duox
Associated Insertion(s)
Carried in Construct
P{UAS-Duox.ΔPHD}
Key Links
Transgenic product class
inframe_deletion
(Ha et al., 2005)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Ha et al., 2005)
Mutagen
in vitro construct
(Ha et al., 2005)
Progenitor genotype
Carried in construct
P{UAS-Duox.ΔPHD}
Cytology
Description

UASt regulatory sequences drive expression of Duox lacking the PHD (the region corresponding to amino acids 1 to 566 have been deleted and a signal peptide has been added to the N-terminus).

(Ha et al., 2005)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Duox
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      DuoxΔPHD.UAS/Scer\GAL4da.G32 fails to rescue DuoxRNAi.UAS

      (Ha et al., 2005)

      DuoxΔPHD.UAS/Scer\GAL4cad-em459 fails to rescue DuoxRNAi.UAS

      (Ha et al., 2005)
      Comments

      The survival rates of flies expressing DuoxdsRNA.Scer\UAS under the control of Scer\GAL4cad-em459 after natural infection with "Ecc15" (P.carotovorum.carotovorum) are not markedly improved if they co-express DuoxΔPHD.Scer\UAS. The persistence of ingested "Ecc15" (P.carotovorum.carotovorum) bacteria that is seen in the intestinal tracts of flies expressing DuoxdsRNA.Scer\UAS under the control of Scer\GAL4da.G32 is not rescued by co-expression of DuoxΔPHD.Scer\UAS.

      (Ha et al., 2005)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      CyΔPHD.Scer\UAS
      DuoxΔPHD.Scer\UAS
      DuoxΔPHD.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (2)