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General Information
Symbol
Dmel\psqrev9
Species
D. melanogaster
Name
FlyBase ID
FBal0191540
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
GS88A8, eyeful
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Nucleotide change:

G10561955A

Reported nucleotide change:

G?A

Comment:

Position of mutation on reference sequence inferred by FlyBase curator based on author statement. See Supplementary Data Figure S3. Mutation is in splice donor site leading to the retention of the 72 bp intron. This causes in frame addition of 24 aa within the BTB/POZ domain.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

G to A mutation in a splicing donor site The P{GSV1}lolaGS88A8 insertion is still present on the chromosome.

Insertion components
P{GSV1}GS88A8
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Flies expressing DlScer\UAS.cDa under the control of Scer\GAL4ey.PH and also carrying lolaGS88A8 and psqrev9 do not produce eye tumours or metastases.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer

Induced on: the P{GSV1}lolaGS88A8 chromosome. Selected as: a mutation that reverts the tumour phenotype caused by overexpression of both psq and lola from the P{GSV1}lolaGS88A8 insertion under the control of Scer\GAL4ey.PH in the presence of DlScer\UAS.cDa.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (2)