FlyBase Allele Report: Dmel\babo[b.UAS]

General Information

Symbol

Dmel\babo^b.UAS

Species

D. melanogaster

Name

FlyBase ID

FBal0191917

Feature type

allele

Associated gene

Dmel\babo

Associated Insertion(s)

Carried in Construct

P{UAS-babo.b}

Also Known As

UAS-babo-b

Key Links

Transgenic product class

wild_type

(Zheng et al., 2006)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Zheng et al., 2006)

Mutagen

in vitro construct

(Zheng et al., 2006)

Progenitor genotype

Carried in construct

P{UAS-babo.b}

Cytology

Description

UAS regulatory sequences drive expression of the a isoform of babo.

(Zheng et al., 2006)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

babo

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

Co-expression of daw^Scer\UAS.cSa, babo^a.Scer\UAS and babo^b.Scer\UAS in the wing under the control of Scer\GAL4^A9 does not result in wing vein patterning defects.

(Jensen et al., 2009)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Scer\GAL4^insc-Mz1407, babo^b.UAS, babo^a.UAS rescues babo³²/babo²⁶

(Zhu et al., 2008)

babo^b.UAS, Scer\GAL4^wor.PA, babo^a.UAS rescues babo³²/babo²⁶

(Zhu et al., 2008)

babo^b.UAS/Scer\GAL4^da.G32 rescues babo²⁶/babo⁵²

(Zhu et al., 2008)

babo^b.UAS/Scer\GAL4^Act5C.PP rescues babo⁵²

(Ting et al., 2007)

babo^b.UAS/Scer\GAL4^Act5C.PP rescues babo⁹

(Ting et al., 2007)

Partially rescues

babo^b.UAS/Scer\GAL4^Tab2-201Y partially rescues babo⁹

(Zheng et al., 2006)

Fails to rescue

babo^b.UAS, babo^a.UAS, Scer\GAL4^ey.PH fails to rescue babo³²/babo²⁶

(Zhu et al., 2008)

babo^b.UAS, Scer\GAL4^repo, babo^a.UAS fails to rescue babo³²/babo²⁶

(Zhu et al., 2008)

Comments

Expression of babo^b.Scer\UAS under the control of Scer\GAL4^da.G32 rescues the photoreceptor axon targeting defects and small brain phenotype of babo²⁶/babo⁵² mutants.

Co-expression of both babo^a.Scer\UAS and babo^b.Scer\UAS under the control of Scer\GAL4^ey.PH or Scer\GAL4^repo does not rescue the photoreceptor axon targeting defects of babo²⁶/babo³² mutants.

Co-expression of both babo^a.Scer\UAS and babo^b.Scer\UAS under the control of Scer\GAL4¹⁴⁰⁷ or Scer\GAL4^wor.PA rescues the brain size and photoreceptor axon targeting defects of babo²⁶/babo³² mutants.

(Zhu et al., 2008)

Expression of babo^b.Scer\UAS under the control of Scer\GAL4^Tab2-201Y in babo⁹ dorsal cluster neuron clones provides a significant but incomplete rescue of dorsal cluster neuron defects. However, expression of this transgene in γ neurons fails to rescue mushroom body remodelling defects.

(Zheng et al., 2006)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

babo^b.Scer\UAS

babo^b.UAS

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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