FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\nesEY22898
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General Information
Symbol
Dmel\nesEY22898
Species
D. melanogaster
Name
FlyBase ID
FBal0192709
Feature type
allele
Associated gene
Dmel\nes
Associated Insertion(s)
P{EPgy2}nesEY22898
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Bellen, 2006.8.3)
Progenitor genotype
Associated Insertion(s)
P{EPgy2}nesEY22898
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{EPgy2}
Regulatory region(s)
UASp
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Maternal overexpression of nesEY22898 under the control of Scer\GAL4tub causes 30% of embryos to degenerate.

      (Steinhauer et al., 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      Scer\GAL4Tub.PU, nesEY22898 has embryo phenotype, enhanceable by wun2αTub84B.Tag:MYC

      (Steinhauer et al., 2009)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Maternal overexpression of both nesEY22898 and wun2alphaTub84B.T:Hsap\MYC under the control of Scer\GAL4tub causes both a quantitative and a qualitative enhancement of the nesEY22898 embryo degeneration phenotype.

      (Steinhauer et al., 2009)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      nesEY22898
      (Bellen, 2006.8.3)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)