FlyBase Allele Report: Dmel\LUBEL[MB00197]

General Information

Symbol

Dmel\LUBEL^MB00197

Species

D. melanogaster

Name

FlyBase ID

FBal0192782

Feature type

allele

Associated gene

Dmel\LUBEL

Associated Insertion(s)

Mi{ET1}LUBEL^MB00197

Carried in Construct

Also Known As

lubel^Mi

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Associated Insertion(s)

Mi{ET1}LUBEL^MB00197

Cytology

Description

Allele components

Component

Use(s)

Inserted element

Mi{ET1}

enhancer trap

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2L:6,764,587..6,764,587 [+]

(Kawaguchi et al., 2026, Aalto et al., 2019, Bellen, 2006.8.3)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal immune response | adult stage

(Aalto et al., 2019)

increased occurrence of cell division | adult stage | conditional

(Aalto et al., 2019)

short lived | conditional

(Aalto et al., 2019)

Phenotype Manifest In

adult gut | conditional

(Aalto et al., 2019)

Detailed Description

Statement

Reference

LUBEL^MB00197 individuals are sensitive to Ecc15 bacterial infection via feeding and, unlike controls, do not show the expected increase in mitotic index in the intestine. However, they are not sensitive to Ecc15 or Micrococcus luteus bacterial infection via septic injury.

LUBEL^MB00197 individuals fed with Ecc15 show a significantly higher bacterial load than controls.

(Aalto et al., 2019)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

LUBEL^MB00197 is a non-enhancer of visible phenotype of Scer\GAL4^GMR.PF, cindr^{RNAi.PC.PD.UAS}

(Ketosugbo et al., 2017)

NOT Suppressor of

Statement

Reference

LUBEL^MB00197 is a non-suppressor of visible phenotype of Scer\GAL4^GMR.PF, cindr^{RNAi.PC.PD.UAS}

(Ketosugbo et al., 2017)

Phenotype Manifest In

NOT Enhancer of

Statement

Reference

LUBEL^MB00197 is a non-enhancer of eye phenotype of Scer\GAL4^GMR.PF, cindr^{RNAi.PC.PD.UAS}

(Ketosugbo et al., 2017)

NOT Suppressor of

Statement

Reference

LUBEL^MB00197 is a non-suppressor of eye phenotype of Scer\GAL4^GMR.PF, cindr^{RNAi.PC.PD.UAS}

(Ketosugbo et al., 2017)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

22725

y¹ w^67c23; Mi{ET1}LUBEL^MB00197

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

CG11321^MB00197

(Bellen, 2006.8.3)

LUBEL^MB00197

LUBEL^MI

(Kawaguchi et al., 2026)

lubel^Mi

(Aalto et al., 2019)

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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