FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\LarUAS.Tag:HA
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General Information
Symbol
Dmel\LarUAS.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0193546
Feature type
allele
Associated gene
Dmel\Lar
Associated Insertion(s)
Carried in Construct
P{UAS-HA-Lar}
Also Known As
UAS-HA-LAR
Key Links
Transgenic product class
wild_type
(Hofmeyer et al., 2006)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Hofmeyer et al., 2006)
Mutagen
in vitro construct
(Hofmeyer et al., 2006)
Progenitor genotype
LarGMR.Tag:SS(wg),Tag:HA
(Hofmeyer et al., 2006)
Carried in construct
P{UAS-HA-Lar}
Cytology
Description

UASt regulatory sequences drive expression of a Lar that is tagged at the N-terminal end with Tag:HA.

(Hofmeyer et al., 2006)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Lar
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Suppressor of
      Statement
      Reference

      Scer\GAL4elav-C155/LarUAS.Tag:HA is a non-suppressor of abnormal neuroanatomy phenotype of Liprin-αoos

      (Hofmeyer et al., 2006)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Overexpression of LarScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4elav-C155 in a Liprin-αoos mutant background has little effect on R7 targeting.

      (Hofmeyer et al., 2006)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4elav-C155/LarUAS.Tag:HA rescues LarC12/Lar2127

      (Hofmeyer and Treisman, 2009)

      Scer\GAL4elav-C155/LarUAS.Tag:HA rescues LarC12/Lar2127

      (Hofmeyer et al., 2006)

      LarUAS.Tag:HA rescues LarC12/Lar2127

      (Hofmeyer, 2006)
      Comments

      Expression of LarScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4elav-C155 in LarC12/Lar2127 mutant larvae rescues axon mistargeting in the eye discs, and synaptic growth at the neuromuscular junction.

      (Hofmeyer and Treisman, 2009)

      Expression of LarScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4elav-C155 rescues R7 targeting in Lar2127/LarC12 mutants.

      (Hofmeyer et al., 2006)

      Expression of LarΔC.Scer\UAS.T:wg,T:Ivir\HA1 under the control of Scer\GAL4T155 fails to rescue the egg elongation phenotype observed in stage 14 oocytes from Lar2127/LarC12 mutants and indeed exacerbates the phenotype, with approximately 44% of the oocytes displaying a 'rounded phenotype', compared to approximately 30% in the Lar2127/LarC12 mutant.

      (Hofmeyer, 2006)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      LarScer\UAS.T:Ivir\HA1
      LarUAS.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (5)