FB2026_02 , released June 18, 2026
Allele: Dmel\cicUAS.cLa
Open Close
General Information
Symbol
Dmel\cicUAS.cLa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Lam
FlyBase ID
FBal0193730
Feature type
allele
Associated gene
Dmel\cic
Associated Insertion(s)
Carried in Construct
P{UAS-cic.L}
Also Known As
UAS-cic
Key Links
Transgenic product class
wild_type
(Lam et al., 2006)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Lam et al., 2006)
Mutagen
in vitro construct
(Lam et al., 2006)
Progenitor genotype
Carried in construct
P{UAS-cic.L}
Cytology
Description

UAS regulatory sequences drive expression of cic.

(Lam et al., 2006)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
cic
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of cicScer\UAS.cLa under the control of Scer\GAL4cv-c-C5 results in a substantial reduction in wing veins, as compared to controls.

      (Forés et al., 2017)

      Expression of cicScer\UAS.cLa in the eye, driven by Scer\GAL4GMR.PF, causes mild ommatidial disorganization.

      Expression of cicScer\UAS.cLa, under the control of Scer\GAL4C5, causes the loss of veins in the posterior part of the wing, including the posterior crossvein.

      (Lam et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      cicUAS.cLa, Scer\GAL4GMR.PF is a suppressor of visible phenotype of Hsap\ATXN182Q.UAS, Scer\GAL4GMR.PF

      (Lam et al., 2006)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Coexpression of cicScer\UAS.cLa and Hsap\ATX182Q.Scer\UAS, both under the control of Scer\GAL4GMR.PF, results in a milder eye phenotype than expression of Hsap\ATX182Q.Scer\UAS alone; there is less ommatidial disorganization and fusion and the interommatidial bristles are partially restored.

      Coexpression of cicScer\UAS.cLa and Hsap\ATX182Q.Scer\UAS, under the control of Scer\GAL4C5, results in restoration of the posterior crossvein, which is missing in flies expressing either transgene separately.

      (Lam et al., 2006)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      cicScer\UAS.cLa
      cicUAS.cLa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Lam
      Secondary FlyBase IDs
        References (3)