FB2026_02 , released June 18, 2026
Allele: Hsap\CDC73UAS.cMa
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General Information
Symbol
Hsap\CDC73UAS.cMa
Species
H. sapiens
Name
Saccharomyces cerevisiae UAS construct a of Mosimann
FlyBase ID
FBal0193890
Feature type
allele
Associated gene
Hsap\CDC73
Associated Insertion(s)
Carried in Construct
P{UAS-HRPT2.M}
Also Known As
UAS-HRPT2
Key Links
Transgenic product class
wild_type
(Mosimann et al., 2006)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Mosimann et al., 2006)
Mutagen
in vitro construct
(Mosimann et al., 2006)
Progenitor genotype
Carried in construct
P{UAS-HRPT2.M}
Cytology
Description

UAS regulatory sequences drive expression of full-length Hsap\CDC73.

(Mosimann et al., 2006)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Hsap\CDC73
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Hsap\CDC73UAS.cMa, Scer\GAL4insc-Mz1407 is a suppressor of larval neuroblast | increased number phenotype of Scer\GAL4insc-Mz1407, hyxKK101075

      (Deng et al., 2022)

      Hsap\CDC73UAS.cMa, Scer\GAL4insc-Mz1407 is a suppressor of type I neuroblast | increased number phenotype of Scer\GAL4insc-Mz1407, hyxKK101075

      (Deng et al., 2022)

      Hsap\CDC73UAS.cMa, Scer\GAL4insc-Mz1407 is a suppressor of type II neuroblast | increased number phenotype of Scer\GAL4insc-Mz1407, hyxKK101075

      (Deng et al., 2022)

      Hsap\CDC73UAS.cMa/Scer\GAL4wor.PA is a suppressor of larval neuroblast | increased number | somatic clone phenotype of hyxHT622

      (Deng et al., 2022)

      Scer\GAL4insc-Mz1407/Hsap\CDC73UAS.cMa is a suppressor of larval neuroblast | increased number | somatic clone phenotype of hyxHT622

      (Deng et al., 2022)

      Hsap\CDC73UAS.cMa/Scer\GAL4wor.PA is a suppressor of type I neuroblast | increased number | somatic clone | larval stage phenotype of hyxHT622

      (Deng et al., 2022)

      Hsap\CDC73UAS.cMa/Scer\GAL4wor.PA is a suppressor of type II neuroblast | increased number | somatic clone | larval stage phenotype of hyxHT622

      (Deng et al., 2022)

      Scer\GAL4insc-Mz1407/Hsap\CDC73UAS.cMa is a suppressor of type I neuroblast | increased number | somatic clone | larval stage phenotype of hyxHT622

      (Deng et al., 2022)

      Scer\GAL4insc-Mz1407/Hsap\CDC73UAS.cMa is a suppressor of type II neuroblast | increased number | somatic clone | larval stage phenotype of hyxHT622

      (Deng et al., 2022)

      Hsap\CDC73UAS.cMa, Scer\GAL4nub-AC-62 is a suppressor | partially of wing blade phenotype of Scer\GAL4nub-AC-62, ci75.UAS

      (Mosimann et al., 2009)

      Hsap\CDC73UAS.cMa, Scer\GAL4salm.E is a suppressor of wing margin phenotype of Scer\GAL4salm.E, lgs17E.UAS

      (Mosimann et al., 2006)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Co-expression of Hsap\CDC73Scer\UAS.cMa with Scer\GAL4nub-AC-62 driven ci75.Scer\UAS leads to a striking, albeit incomplete, reversion to wild-type wing morphology.

      (Mosimann et al., 2009)

      Coexpression of the hyx human homologue, Hsap\CDC73Scer\UAS.cMa, with lgs17E.Scer\UAS (driven by Scer\GAL4salm.E) suppresses the notched wing phenotype of lgs17E.Scer\UAS flies.

      (Mosimann et al., 2006)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Hsap\CDC73Scer\UAS.cMa
      Hsap\CDC73UAS.cMa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Mosimann
      Secondary FlyBase IDs
        References (3)