FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\foiE584A.E588A.D591A.UAS.Tag:HA
Open Close
General Information
Symbol
Dmel\foiE584A.E588A.D591A.UAS.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0194009
Feature type
allele
Associated gene
Dmel\foi
Associated Insertion(s)
Carried in Construct
P{UAS-foi.E584A.E588A.D591A.HA}
Key Links
Transgenic product class
missense_variant
(Mathews et al., 2006)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Mathews et al., 2006)
Mutagen
in vitro construct
(Mathews et al., 2006)
Progenitor genotype
foi704.UAS.Tag:HA
(Mathews et al., 2006)
Carried in construct
P{UAS-foi.E584A.E588A.D591A.HA}
Cytology
Description

Amino acid replacement: E584A.

(Mathews et al., 2006)

The mutated amino acid residues are all within the 'HELP' domain.

(Mathews et al., 2006)

Amino acid replacement: E588A.

(Mathews et al., 2006)

Amino acid replacement: D591A.

(Mathews et al., 2006)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
foi
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      foiE584A.E588A.D591A.UAS.Tag:HA fails to rescue foi20.71

      (Mathews et al., 2006)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Carried in a plasmid and transfected into S2 cells to study the subcellular localization of the expressed product.

      (Mathews et al., 2006)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      foiE584A.E588A.D591A.Scer\UAS.T:Ivir\HA1
      foiE584A.E588A.D591A.UAS.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (2)