FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\CkIIβVIIb.UAS
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General Information
Symbol
Dmel\CkIIβVIIb.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0194272
Feature type
allele
Associated gene
Dmel\CkIIβ
Associated Insertion(s)
Carried in Construct
P{UAS-CkIIβ.VIIb}
Key Links
Transgenic product class
cDNA
(Jauch et al., 2006)
wild_type
(Jauch et al., 2006)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Jauch et al., 2006)
wild_type
(Jauch et al., 2006)
Mutagen
in vitro construct
(Jauch et al., 2006)
Progenitor genotype
Carried in construct
P{UAS-CkIIβ.VIIb}
Cytology
Description

UASt regulatory sequences drive expression of a EcoRI-XbaI fragment containing a CkIIβ-VIIb cDNA. (Exon VIIa sequences on clone RE31047 were deleted to generate a cDNA encoding CkIIβ-VIIb, called RE31047[VIIb]).

(Jauch et al., 2006)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
CkIIβ
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of CkIIβVIIb.Scer\UAS under the control of Scer\GAL4αTub84B.PL induces lethality in five out of eight tested CkIIβVIIb.Scer\UAS transgenic lines.

      Expression of CkIIβVIIb.Scer\UAS under the control of Scer\GAL4αTub84B.PL in a CkIIβmbuΔA26-2L background results in mushroom body calyces that are proportionally larger than those of wild type flies.

      (Jauch et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      CkIIβVIIb.UAS/Scer\GAL4αTub84B.PL rescues CkIIβmbuΔA26-2L

      (Jauch et al., 2006)
      Comments

      When expressed under the control of Scer\GAL4αTub84B.PL, not all of the CkIIβVIIb.Scer\UAS transgenic lines rescue the lethality of CkIIβmbuΔA26-2L flies.

      (Jauch et al., 2006)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      CkIIβVIIb.Scer\UAS
      CkIIβVIIb.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (2)