FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Myo31DFsouther
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General Information
Symbol
Dmel\Myo31DFsouther
Species
D. melanogaster
Name
FlyBase ID
FBal0195151
Feature type
allele
Associated gene
Dmel\Myo31DF
Associated Insertion(s)
gypsy{}Myo31DFsouther
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    gypsy{}Myo31DFsouther
    Cytology
    Description

    gypsy insertion in the 5' untranslated region.

    (Hozumi et al., 2006)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Myo31DFsouther mutants exhibit recessive left-right symmetry defects in the embryonic midgut and hindgut. In contrast, the foregut of Myo31DFsouther mutant embryos show normal handedness, indicating that these left-right defects are heterotaxic. In addition, in adult Myo31DFsouther mutant flies, the laterality of the testis and hindgut is reversed.

        (Taniguchi et al., 2007)

        75.7% of homozygous embryos show synchronous inversion of the normal left-right asymmetry of the midgut and hindgut, such that in these embryos the midgut and hindgut are a mirror image of those in wild-type embryos. The handedness of the foregut is normal in these embryos.

        The normal left-right asymmetry of the hindgut is inversed in 40.7% of homozygous adults, while in 29.6% of cases the hindgut is deformed. The handedness of the spiral of the testis is reversed in 73.7% of homozygous males, while in 18.4% of cases the testis is deformed.

        (Hozumi et al., 2006)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer

        Separable from: P{GSV6}GS14508.

        (Hozumi et al., 2006)
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        Myo31DFsouther
        (Taniguchi et al., 2007, Hozumi et al., 2006)
        Name Synonyms
        Secondary FlyBase IDs
          References (2)