FB2026_02 , released June 18, 2026
Allele: Dmel\opaB28
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General Information
Symbol
Dmel\opaB28
Species
D. melanogaster
Name
FlyBase ID
FBal0196145
Feature type
allele
Associated gene
Dmel\opa
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Mahoney et al., 2006)
Progenitor genotype
Cytology
Description

Amino acid replacement: Y275N.

(Mahoney et al., 2006)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3R:4,853,931..4,853,931 [+]
Nucleotide change:

T4853931A

Amino acid change:

Y276N | opa-PA; Y276N | opa-PB

Reported amino acid change:

Y275N

Comment:

Approximate location of lesion based on the reported Y275N change. Residue 275 is a K so mutation was mapped as Y276N. Note residue 275 could also change to an N with a single base change.

(Mahoney et al., 2006)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Other
      Statement
      Reference

      Psn143, opaB28 has visible phenotype

      (Mahoney et al., 2006)

      Psn143/Psn[+], opaB28 has visible phenotype

      (Mahoney et al., 2006)
      Phenotype Manifest In
      Other
      Statement
      Reference

      Psn143, opaB28 has eye phenotype

      (Mahoney et al., 2006)

      Psn143/Psn[+], opaB28 has vibrissal bristle phenotype

      (Mahoney et al., 2006)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      opaB28 Psn143/+ flies have tufted vibrissae.

      (Mahoney et al., 2006)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      B28
      (Mahoney et al., 2006)
      opaB28
      Name Synonyms
      Secondary FlyBase IDs
        References (1)