FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\PisninaE.PW
Open Close
General Information
Symbol
Dmel\PisninaE.PW
Species
D. melanogaster
Name
neither inactivation nor afterpotential E promoter construct of Wang
FlyBase ID
FBal0196212
Feature type
allele
Associated gene
Dmel\Pis
Associated Insertion(s)
Carried in Construct
P{ninaE-Pis.W}
Key Links
Transgenic product class
wild_type
(Wang and Montell, 2006)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Wang and Montell, 2006)
Mutagen
in vitro construct
(Wang and Montell, 2006)
Progenitor genotype
Carried in construct
P{ninaE-Pis.W}
Cytology
Description

A 3kb ninaE promoter drives expression of Pis. The construct has a 0.5kb region from the SV40 virus that provides signals for polyadenylation and 3' end cleavage of RNA.

(Wang and Montell, 2006)
Allele components
Component
Use(s)
Regulatory region(s)
ninaE
Encoded product / tool
Pis
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      PisninaE.PW is a suppressor of rhabdomere phenotype of Cds1

      (Wang and Montell, 2006)

      PisninaE.PW is a suppressor of rhabdomere phenotype of rdgB9

      (Wang and Montell, 2006)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The degeneration of rhabdomeres in rdgB9 flies is greatly suppressed by expression of PisninaE.PW.

      Expression of PisninaE.PW partially suppresses the CdsA1 retinal degeneration phenotype; after 5 days under a light/dark cycle, PisninaE.PW; CdsA1 flies have ommatidia that contain several rhabdomeres whereas almost all rhabdomeres have degenerated in CdsA1 flies at this stage.

      (Wang and Montell, 2006)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      PisninaE.PW
      Name Synonyms
      neither inactivation nor afterpotential E promoter construct of Wang
      Secondary FlyBase IDs
        References (1)