FB2026_02 , released June 18, 2026
Allele: Dmel\TraxW151stop
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General Information
Symbol
Dmel\TraxW151stop
Species
D. melanogaster
Name
FlyBase ID
FBal0196829
Feature type
allele
Associated gene
Dmel\Trax
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    Amino acid replacement: W151term.

    (Claussen et al., 2006)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    point_mutation
    3R:15,362,276..15,362,276 [+]
    Nucleotide change:

    G15362276A

    Amino acid change:

    W151term | Trax-PB; W151term | Trax-PC

    Reported amino acid change:

    W151term

    Comment:

    G to A nucleotide change at the second or third position of the Trp codon leads to a nonsense mutation (exact site of mutation unspecified). Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

    (Claussen et al., 2006)
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        The recombination frequency seen in the b-pr and pr-cn intervals are similar in TraxW151stop/Df(3R)Exel6174 females compared to controls.

        No differences in the rate of X chromosome nondisjunction are seen between TraxW151stop/Df(3R)Exel6174 females and males and control flies.

        TraxW151stop/Df(3R)Exel6174 flies are not more sensitive to γ-irradiation than control flies.

        (Claussen et al., 2006)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Other
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer

        Separable from: fs(3)H813H813.

        (Claussen et al., 2006)

        The "H813" chromosome is female sterile when homozygous and has a molecular lesion in the Trax gene (TraxW151stop). However the female sterility appears not to be due to an absence of functional Trax protein, but due to a separable lesion (fs(3)H813H813), since flies carrying the "H813" chromosome over a deficiency for Trax are fertile.

        (Claussen et al., 2006)
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        TraxW151stop
        traxW151*
        (Claussen et al., 2006)
        Name Synonyms
        Secondary FlyBase IDs
          References (1)