FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Nf1GRD.UAS.Tag:HA
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General Information
Symbol
Dmel\Nf1GRD.UAS.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0197128
Feature type
allele
Associated gene
Dmel\Nf1
Associated Insertion(s)
Carried in Construct
P{UAS-Nf1.GRD}
Also Known As
UAS-GRD
Key Links
Transgenic product class
inframe_deletion
(Walker et al., 2006)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Walker et al., 2006)
Mutagen
in vitro construct
(Walker et al., 2006)
Progenitor genotype
Carried in construct
P{UAS-Nf1.GRD}
Cytology
Description

UAS regulatory sequences drive expression of the Nf1 GAP-related domain (amino acids 1214-1574), which is tagged at the C-terminal end with Tag:HA.

(Walker et al., 2006)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Nf1
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Nf1GRD.UAS.Tag:HA/Scer\GAL4Act5C.PI rescues Nf1E2

      (Walker et al., 2006)

      Nf1GRD.UAS.Tag:HA/Scer\GAL4Ras64B.PW rescues Nf1E2

      (Walker et al., 2006)

      Nf1GRD.UAS.Tag:HA/Scer\GAL4Ras85D.PW rescues Nf1E2

      (Walker et al., 2006)
      Partially rescues

      Nf1GRD.UAS.Tag:HA/Scer\GAL4C23 partially rescues Nf1E2

      (Walker et al., 2006)
      Fails to rescue

      Nf1GRD.UAS.Tag:HA/Scer\GAL4repo fails to rescue Nf1E2

      (Walker et al., 2006)
      Comments

      The pupal size defect seen in Nf1E2 animals is rescued by expression of Nf1<up>GRD.Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4Act5C.PI, is partially rescued by expression of Nf1<up>GRD.Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4C23 and is not rescued by expression of Nf1<up>GRD.Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4repo.

      (Walker et al., 2006)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Nf1GRD.Scer\UAS.T:Ivir\HA1
      Nf1GRD.UAS.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (2)