FlyBase Allele Report: Dmel\Samuel[5D]

General Information

Symbol

Dmel\Samuel^5D

Species

D. melanogaster

Name

FlyBase ID

FBal0197250

Feature type

allele

Associated gene

Dmel\Samuel

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Baker et al., 2007)

Progenitor genotype

Samuel^KG04270

(Baker et al., 2007)

Cytology

Description

Imprecise excision of the insertion in Samuel^KG04270, resulting in a deletion of intronic sequences of Samuel.

(Baker et al., 2007)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal developmental rate | third instar larval stage (with Samuel²⁴)

(Baker et al., 2007)

hyperplasia | third instar larval stage (with Samuel²⁴)

(Baker et al., 2007)

lethal | prepupal stage (with Samuel²⁴)

(Baker et al., 2007)

lethal | third instar larval stage (with Samuel²⁴)

(Baker et al., 2007)

Phenotype Manifest In

imaginal disc (with Samuel²⁴)

(Baker et al., 2007)

larval brain (with Samuel²⁴)

(Baker et al., 2007)

Detailed Description

Statement

Reference

Samuel²⁴/Samuel^5D mutants die as late third instar larvae or early prepupae, with 15% of the animals escaping to adulthood with no apparent defects.

Samuel²⁴/Samuel^5D third instar larvae show an overgrowth phenotype. They show marked delays of up to 10-14 days in pupariation, severe hemolymph-induced bloating, fat clearing and hyperplastic overgrowth of the imaginal discs and brain.

(Baker et al., 2007)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

Samuel²⁴

(Baker et al., 2007)

Rescued by

Samuel^5D/Samuel²⁴ is rescued by Samuel^hs.PB

(Baker et al., 2007)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Samuel^5D

moses^5D

(Baker et al., 2007)

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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