FB2026_02 , released June 18, 2026
Allele: Dmel\meltRNAi.UAS.pTb
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General Information
Symbol
Dmel\meltRNAi.UAS.pTb
Species
D. melanogaster
Name
FlyBase ID
FBal0197834
Feature type
allele
Associated gene
Dmel\melt
Associated Insertion(s)
Carried in Construct
P{UAS-melt.RNAi.Tb}
Key Links
Transgenic product class
RNAi_reagent
(Teleman et al., 2005)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Teleman et al., 2005)
Mutagen
in vitro construct
(Teleman et al., 2005)
Progenitor genotype
Carried in construct
P{UAS-melt.RNAi.Tb}
Cytology
Description

Expression of a hairpin loop of melt sequence (amplified by PCR using tctagaCGCCCACACGTTGCAGCATTG and tctagaGGACTCCCGCGTGCTAAG), separated by an intron space, is under the control of UAS sequences.

(Teleman et al., 2005)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
melt
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      MeltdsRNA.Scer\UAS.pTa; MeltdsRNA.Scer\UAS.pTb; Scer\GAL4αTub84B.PL flies have only about 25% the body fat levels of controls flies.

      (Teleman et al., 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Transfected into flies to study the the phenotypic consequences of dsRNA interference (RNAi) of the melt gene.

      (Teleman et al., 2005)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      meltRNAi.UAS.pTb
      meltdsRNA.Scer\UAS.pTb
      meltdsRNA.UAS.pTb
      Name Synonyms
      Secondary FlyBase IDs
        References (2)