FB2026_03 , released September 17, 2026
Allele: Dmel\Mnn1e173
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General Information
Symbol
Dmel\Mnn1e173
Species
D. melanogaster
Name
FlyBase ID
FBal0198068
Feature type
allele
Associated gene
Dmel\Mnn1
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Papaconstantinou et al., 2005)
Mutagen
P-element activity
(Papaconstantinou et al., 2005)
Progenitor genotype
P{EP}Mnn1EP-GE11370
(Papaconstantinou et al., 2005)
Cytology
Description

Imprecise excision of the P{EP} element, resulting in a 4216bp deletion that begins 661bp upstream of the Mnn1 cDNA sequence and ends at the beginning of exon 4.

(Papaconstantinou et al., 2005)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Although Mnn1e173 mutants are viable in control conditions, they show a high degree of lethality when subjected to heat shock, hypoxia, and oxidative stress. Mnn1e173/Df(2L)spdj2 show similar levels of lethality in response to heat shock.

      (Papaconstantinou et al., 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Mnn1e173
      (Papaconstantinou et al., 2010, Cerrato et al., 2006, Papaconstantinou et al., 2005)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)