FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\wkdMB04624
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General Information
Symbol
Dmel\wkdMB04624
Species
D. melanogaster
Name
FlyBase ID
FBal0198350
Feature type
allele
Associated gene
Dmel\wkd
Associated Insertion(s)
Mi{ET1}wkdMB04624
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    Mi{ET1}wkdMB04624
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Inserted element
    Mi{ET1}
    Encoded product / tool
    GAL4
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Terminal cells mutant for wkdMB04624 exhibit a decreased number of branches and a "U-turn" phenotype, in which seamless tubes execute a series of 180[o] turns.

        (Schottenfeld-Roames and Ghabrial, 2012)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        NOT suppressed by
        Statement
        Reference

        wkdMB04624 has terminal tracheal cell phenotype, non-suppressible by snX2/sn[+]

        (Schottenfeld-Roames and Ghabrial, 2012)

        wkdMB04624 has terminal tracheal cell phenotype, non-suppressible by snX2/Df(1)C128

        (Schottenfeld-Roames and Ghabrial, 2012)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        Heterozygous snX2 does not suppress the tracheal defects seen in wkdMB04624/Df(3R)Exel6276 mutant larvae. No suppression is seen in a snX2/Df(1)C128 background.

        (Schottenfeld-Roames and Ghabrial, 2012)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Rescued by

        wkdMB04624/Df(3R)Exel6276 is rescued by wkd+t3.9

        (Schottenfeld-Roames and Ghabrial, 2012)
        Comments

        Expression of wkd+t3.9 rescues the tracheal defects and lethality seen in wkdMB04624/Df(3R)Exel6276 mutants.

        (Schottenfeld-Roames and Ghabrial, 2012)
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        wkdMB04624
        (Bellen, 2007.8.20)
        wkdMI
        (Schottenfeld-Roames and Ghabrial, 2012)
        Name Synonyms
        Secondary FlyBase IDs
          References (2)