FB2026_03 , released September 17, 2026
Allele: Dmel\emcG4.1
Open Close
General Information
Symbol
Dmel\emcG4.1
Species
D. melanogaster
Name
FlyBase ID
FBal0198468
Feature type
allele
Associated gene
Dmel\emc
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Saito et al., 2002)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      emcG4.1/Df(3L)Fpa1 embryos look normal at early embryonic stages but at stage 17 the shape of the head and midgut appears abnormal. Head development is retarded around stage 15; the dorsal fold does not migrate anteriorly so that the pharyngeal region remains exposed as an anterior protrusion on the dorsal side of the head, even after denticle belts have formed. The midgut fails to develop and appears as a thick smooth tube without constrictions in most stage 17 embryos. Dorsal closure does not occur properly in the mutant embryos, so that the dorsal midline is inappropriately shaped, pinched or puckered. The fas2-positive longitudinal tracts in the central nervous system appear normal.

      (Saito et al., 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      emc1

      (Saito et al., 2002)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Selected as: A mutation that is lethal in combination with Df(3L)Fpa1.

      (Saito et al., 2002)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      G4.1
      (Saito et al., 2002)
      emcG4.1
      l(3)61DaG4.1
      (Saito et al., 2002)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)