UASt regulatory sequences drive expression of an inverted repeat.
Expression of CG31741GD1756 under the control of Scer\GAL4Hml.Δ results in significantly reduced survival and increased parasite load when infected with Leishmania amastigotes, along with a significant decrease in intracellular parasites in the hemocytes, but no significant difference in the number of promastigotes at 8 days post-infection, as compared to wild type.
Adults expressing CG31741GD1756 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.