UASt regulatory sequences drive expression of an inverted repeat.
Adults expressing LaGD1476 under the control of the cardioblast-specific Scer\GAL4tin.CΔ4 driver show significantly reduced survival on day 6 after a shift to 29[o]C compared to control flies.
Expression of LaGD1476 under the control of the cardioblast-specific Scer\GAL4tin.CΔ4 driver results in viable flies or partial lethality, depending on the particular P{GD1476} insertion line used.
Adults expressing LaGD1476 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.
Expression of LaGD1476 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) results in viable flies or partial lethality, depending on the particular P{GD1476} insertion line used.
Depending on the insertion line used, expression under the control of Scer\GAL4Mef2.PR can result in flightless flies.
Expression under the control of Scer\GAL4Mef2.PR results in grossly normal adult indirect flight muscles.
Expression under the control of Scer\GAL4Mef2.PR results in morphologically wild-type myofibrils in the adult indirect flight muscles.
Expression under the control of Scer\GAL4Mef2.PR results in wild-type sarcomeres in the adult indirect flight muscles.
Expression under the control of Scer\GAL4pnr-MD237 results in loss of bristles on the notum in 0% or 50-60% of the Scer\GAL4pnr-MD237 expression domain, depending on the insertion line used.
Expression under the control of Scer\GAL4pnr-MD237 results in bristle morphology defects on the notum in 50-60% or 80-90% of the Scer\GAL4pnr-MD237 expression domain, depending on the insertion line used.