UASt regulatory sequences drive expression of an inverted repeat.
Adults expressing bcn92GD10495 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) can show significantly reduced avoidance of noxious temperature (46[o]C) compared to control flies, depending on the particular P{GD10495} insertion line used.
Depending on the insertion line used, expression under the control of Scer\GAL4Mef2.PR can result in defects in locomotion, early pupal lethality or late pupal lethality.
Expression under the control of Scer\GAL4pnr-MD237 may result in semi-lethality, depending on the insertion line used.