FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Cad99CRNAi.UAS
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General Information
Symbol
Dmel\Cad99CRNAi.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0212156
Feature type
allele
Associated gene
Dmel\Cad99C
Associated Insertion(s)
Carried in Construct
P{UAS-Cad99C.RNAi}
Key Links
Transgenic product class
RNAi_reagent
(D'Alterio et al., 2005)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(D'Alterio et al., 2005)
Mutagen
in vitro construct
(D'Alterio et al., 2005)
Progenitor genotype
Carried in construct
P{UAS-Cad99C.RNAi}
Cytology
Description

1.1kb of Cad99C coding sequence (342-1436bp) in reverse (3'-5') orientation is attached to a 0.5kb linker containing two Cad99C introns, followed by a 0.7kb fragment of the 1.1kb Cad99C coding sequence in forward (5'-3') orientation.

(D'Alterio et al., 2005)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Cad99C
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In

      microvillus & follicle cell, with Scer\GAL4FRT.Rnor\Cd2.Act5C

      (D'Alterio et al., 2005)
      Detailed Description
      Statement
      Reference

      Expression of Cad99CScer\UAS.dsRNA in follicle cells exhibit a range of defects of microvilli. Microvilli appear substantially shorter than in wild-type. In many cases, apical protrusions appear reduced in number, and they form an irregular, spiky pattern, suggesting that microvilli are abnormally shaped and may be clumped. In other cases, no obvious protrusions are detected or only few microvilli with an abnormal, wavy shape protruded from the apical surface.

      (D'Alterio et al., 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      Cad99CRNAi.UAS
      Cad99CScer\UAS.dsRNA
      Cad99CdsRNA.Scer\UAS
      Cad99CdsRNA.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (2)