FlyBase Allele Report: Scer\GAL4[FRT.Rnor\Cd2.Act5C]

General Information

Symbol

Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

Species

S. cerevisiae

Name

FlyBase ID

FBal0058800

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

Carried in Construct

P{GAL4-Act5C(FRT.CD2).P}

Also Known As

Act>CD2>Gal4, Act5C>CD2>Gal4, actin>CD2>Gal4, Actin5C>CD2>Gal4, act > cd2 > GAL4, act<CD2<GAL4, act<FRT-CD2-FRT<Gal4, actin-FRT-Stop-FRT-Gal4, act>CD2stop>Gal4, actP>CD2>Gal4

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Abu-Shaar and Mann, 1998, Britton and Edgar, 1998, Cadigan et al., 1998, Kozopas et al., 1998, Neufeld et al., 1998, Gorfinkiel et al., 1997, Pignoni and Zipursky, 1997)

Progenitor genotype

Carried in construct

P{GAL4-Act5C(FRT.CD2).P}

Cytology

Description

Act5C promoter is fused upstream of an FRT cassette carrying Rnor\Cd2 sequences, which in turn is fused upstream of sequence encoding a GAL4 driver.

(Pignoni and Zipursky, 1997)

Allele components

Component

Use(s)

Regulatory region(s)

Act5C

Encoded product / tool

GAL4

binary expression system - driver

Also carries

FRT

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Designed for use in mosaic analyses; transcription blocked by FRT-flanked fragment carrying RnorCd2. Expression is of ScerGAL4^Act5C.PP, carried in descendant transposon P{GAL4-Act5C(-FRT).P}; see ScerGAL4^Act5C.PP elsewhere in this table.

(FlyBase Curators, 2017)

Designed for use in mosaic analyses; transcription blocked by FRT-flanked fragment carrying RnorCd2. See expression pattern for ScerGAL4^Act5C.PP, carried in descendant transposon P{GAL4-Act5C(-FRT).P}.

(Pignoni and Zipursky, 1997)

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal cell death | somatic clone, with Rheb^{EP50.084-loxP}

(Barth et al., 2011)

abnormal cell growth, with shi^K44A.UAS

(Hennig et al., 2006)

abnormal mitotic cell cycle, with ct^UAS.cPa

(Sun and Deng, 2005)

abnormal neuroanatomy, with da^Δex1.UAS

(Bhattacharya and Baker, 2011)

abnormal size | somatic clone, with PRL-1^UAS.cPa

(Pagarigan et al., 2013)

abnormal starvation stress response | larval stage | somatic clone, with Pi3K92E^UAS.Tag:MYC

(Cinnamon et al., 2016)

decreased cell size | larval stage | somatic clone, with Pi3K92E^A2860C.UAS

(Cinnamon et al., 2016)

decreased cell size | pupal stage | somatic clone, with Vps36^KK102099

(Anding et al., 2018)

hypoplasia | somatic clone, with PRL-1^UAS.cPa

(Pagarigan et al., 2013)

increased cell growth rate | cell non-autonomous | somatic clone, with nab^EP-nd642

(Suissa et al., 2011)

increased cell growth rate | somatic clone, with Pten^KK109278

(Willecke et al., 2011)

increased cell growth rate | somatic clone, with upd1^UAS.cZa

(Willecke et al., 2011)

increased cell growth rate | somatic clone, with yki^UAS.cHa

(Willecke et al., 2011)

increased cell size, with Hsc70-4^K71S.UAS

(Hennig et al., 2006)

increased cell size, with shi^K44A.UAS

(Hennig et al., 2006)

increased cell size | larval stage | somatic clone, with Akt^{UAS.Tag:HA,Tag:MyrPalm(Lck)}

(Cinnamon et al., 2016)

increased cell size | larval stage | somatic clone | nutrition conditional, with Pi3K92E^UAS.Tag:MYC

(Cinnamon et al., 2016)

increased cell size | pupal stage | somatic clone, with TSG101^GD14295

(Anding et al., 2018)

increased cell size | pupal stage | somatic clone, with Vps13D^GD10464

(Anding et al., 2018)

increased cell size | pupal stage | somatic clone, with Vps13D^HMS01784

(Anding et al., 2018)

lethal - all die before end of P-stage, with Mtmr6^GD11001

(Allen et al., 2020)

lethal - all die before end of P-stage, with Mtmr6^HMS01807

(Allen et al., 2020)

neoplasia | somatic clone, with Ras85D^V12.UAS

(Willecke et al., 2011)

Phenotype Manifest In

adult head capsule | somatic clone, with PRL-1^UAS.cPa

(Pagarigan et al., 2013)

autolysosome | somatic clone | wandering third instar larval stage | nutrition conditional, with car^GD1397

(Takáts et al., 2014)

autolysosome | somatic clone | wandering third instar larval stage | nutrition conditional, with dor^KK102176

(Takáts et al., 2014)

autolysosome | somatic clone | wandering third instar larval stage | nutrition conditional, with lt^HMS00190

(Takáts et al., 2014)

autolysosome | somatic clone | wandering third instar larval stage | nutrition conditional, with Vps11^KK102566

(Takáts et al., 2014)

autolysosome | somatic clone | wandering third instar larval stage | nutrition conditional, with Vps16A^GD13782

(Takáts et al., 2014)

autolysosome | somatic clone | wandering third instar larval stage | nutrition conditional, with Vps39^GD12152

(Takáts et al., 2014)

autophagosome, with Rack1^KK109073

(Érdi et al., 2012)

autophagosome | larval stage | somatic clone, with Aduk^UAS.cBa

(Braden and Neufeld, 2016)

embryonic/first instar larval cuticle, with hh^AC, hh^CD2.UAS

(Gallet et al., 2006)

embryonic/larval crystal cell | ectopic | somatic clone | third instar larval stage, with N^CA.UAS.cUa

(Small et al., 2014)

embryonic/larval epidermis, with hh^AC, hh^CD2.UAS

(Gallet et al., 2006)

embryonic/larval fat body | larval stage, with Rack1^KK109073

(Érdi et al., 2012)

embryonic/larval fat body | larval stage | somatic clone, with Aduk^UAS.cBa

(Braden and Neufeld, 2016)

embryonic/larval fat body | larval stage | somatic clone, with Pi3K92E^A2860C.UAS

(Cinnamon et al., 2016)

embryonic/larval fat body | larval stage | somatic clone | nutrition conditional, with Pi3K92E^UAS.Tag:MYC

(Cinnamon et al., 2016)

embryonic/larval fat body | somatic clone | wandering third instar larval stage | nutrition conditional, with car^GD1397

(Takáts et al., 2014)

embryonic/larval fat body | somatic clone | wandering third instar larval stage | nutrition conditional, with dor^KK102176

(Takáts et al., 2014)

embryonic/larval fat body | somatic clone | wandering third instar larval stage | nutrition conditional, with lt^HMS00190

(Takáts et al., 2014)

embryonic/larval fat body | somatic clone | wandering third instar larval stage | nutrition conditional, with Vps11^KK102566

(Takáts et al., 2014)

embryonic/larval fat body | somatic clone | wandering third instar larval stage | nutrition conditional, with Vps16A^GD13782

(Takáts et al., 2014)

embryonic/larval fat body | somatic clone | wandering third instar larval stage | nutrition conditional, with Vps39^GD12152

(Takáts et al., 2014)

embryonic/larval lymph gland | cell non-autonomous | somatic clone | third instar larval stage, with N^JF01637

(Small et al., 2014)

embryonic/larval oenocyte | larval stage | somatic clone, with Akt^{UAS.Tag:HA,Tag:MyrPalm(Lck)}

(Cinnamon et al., 2016)

embryonic/larval oenocyte | larval stage | somatic clone, with FarO^GD3202

(Cinnamon et al., 2016)

embryonic/larval oenocyte | larval stage | somatic clone, with Pi3K92E^A2860C.UAS

(Cinnamon et al., 2016)

eye | somatic clone, with PRL-1^UAS.cPa

(Pagarigan et al., 2013)

eye disc | somatic clone, with da^Δex1.UAS

(Bhattacharya and Baker, 2011)

eye disc | somatic clone, with emc^EP3620

(Bhattacharya and Baker, 2011)

eye disc anterior to the morphogenetic furrow | somatic clone, with da^Δex1.UAS

(Bhattacharya and Baker, 2011)

eye disc anterior to the morphogenetic furrow | somatic clone, with emc^EP3620

(Bhattacharya and Baker, 2011)

eye disc morphogenetic furrow | somatic clone, with da^Δex1.UAS

(Bhattacharya and Baker, 2011)

fat body, with shi^K44A.UAS

(Hennig et al., 2006)

fat cell | somatic clone | third instar larval stage, with Mtmr6^HMS01807

(Allen et al., 2020)

glycogen granule, with Rack1^KK109073

(Érdi et al., 2012)

haltere | somatic clone, with Sumo^GD10521

(Smith et al., 2011)

imaginal disc, with Hsc70-4^K71S.UAS

(Hennig et al., 2006)

imaginal disc, with shi^K44A.UAS

(Hennig et al., 2006)

lamellocyte | cell non-autonomous | somatic clone | third instar larval stage, with N^JF01637

(Small et al., 2014)

leg | somatic clone, with Sumo^GD10521

(Smith et al., 2011)

macrochaeta | ectopic | somatic clone, with Sumo^GD10521

(Smith et al., 2011)

microvillus & follicle cell, with Cad99C^RNAi.UAS

(D'Alterio et al., 2005)

microvillus & follicle cell, with Cad99C^UAS.fl

(D'Alterio et al., 2005)

microvillus & follicle cell, with Cad99C^{Δcyt.UAS.EGFP}

(D'Alterio et al., 2005)

microvillus & follicle cell, with Cad99C^{Δcyt.UAS.EGFP}, Cad99C^21-5/Cad99C^21-6

(D'Alterio et al., 2005)

midgut | pupal stage | somatic clone, with TSG101^GD14295

(Anding et al., 2018)

midgut | pupal stage | somatic clone, with Vps13B^GD9044

(Anding et al., 2018)

midgut | pupal stage | somatic clone, with Vps13D^GD10464

(Anding et al., 2018)

midgut | pupal stage | somatic clone, with Vps13D^HMS01784

(Anding et al., 2018)

midgut | pupal stage | somatic clone, with Vps36^KK102099

(Anding et al., 2018)

ommatidium | P-stage | somatic clone, with Pi3K92E^CAAX.UAS

(Malin et al., 2024)

ommatidium | P-stage | somatic clone, with Pi3K92E^JF02770

(Malin et al., 2024)

photoreceptor cell R2 | somatic clone, with emc^EP3620

(Bhattacharya and Baker, 2011)

photoreceptor cell R3 | somatic clone, with emc^EP3620

(Bhattacharya and Baker, 2011)

photoreceptor cell R4 | somatic clone, with emc^EP3620

(Bhattacharya and Baker, 2011)

photoreceptor cell R5 | somatic clone, with emc^EP3620

(Bhattacharya and Baker, 2011)

photoreceptor cell R8 | somatic clone, with emc^EP3620

(Bhattacharya and Baker, 2011)

primary lobe of embryonic/larval lymph gland | somatic clone | third instar larval stage, with N^CA.UAS.cUa

(Small et al., 2014)

tertiary lobe of embryonic/larval lymph gland | somatic clone | third instar larval stage, with N^CA.UAS.cUa

(Small et al., 2014)

vitelline membrane, with Cad99C^UAS.fl

(D'Alterio et al., 2005)

vitelline membrane, with Cad99C^{Δcyt.UAS.EGFP}

(D'Alterio et al., 2005)

vitelline membrane, with Cad99C^{Δcyt.UAS.EGFP}, Cad99C^21-5/Cad99C^21-6

(D'Alterio et al., 2005)

wing | somatic clone, with Sumo^GD10521

(Smith et al., 2011)

wing disc, with shi^K44A.UAS

(Hennig et al., 2006)

wing disc | somatic clone, with PRL-1^UAS.cPa

(Pagarigan et al., 2013)

wing pouch, with bi^RNAi.UAS

(Shen et al., 2008)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, nab^EP-nd642 has increased cell growth rate | cell non-autonomous | somatic clone phenotype, enhanceable by BacA\p35^UAS.cHa, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Suissa et al., 2011)

Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} has neoplasia | somatic clone phenotype, enhanceable by dlg1^GD4689, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Willecke et al., 2011)

Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} has neoplasia | somatic clone phenotype, enhanceable by yki^UAS.cHa, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Willecke et al., 2011)

Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} has neoplasia | somatic clone phenotype, enhanceable by upd1^UAS.cZa, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Willecke et al., 2011)

Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, dlg1^GD4689 has neoplasia phenotype, enhanceable by yki^UAS.cHa, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Willecke et al., 2011)

Suppressed by

Statement

Reference

Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, ato^UAS.cJa has abnormal neuroanatomy | somatic clone | third instar larval stage phenotype, suppressible by ase^UAS.cBa/Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Mora et al., 2018)

Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, ato^UAS.cJa has abnormal cell polarity | somatic clone | third instar larval stage phenotype, suppressible by ase^UAS.cBa/Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Mora et al., 2018)

Cbl^L.UAS, Rbf^120a, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} has increased cell death phenotype, suppressible | partially by mir-998^UAS.cTa, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Truscott et al., 2014)

Cbl^S.UAS, Rbf^120a, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} has increased cell death phenotype, suppressible | partially by mir-998^UAS.cTa, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Truscott et al., 2014)

Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, scrib¹ has neoplasia phenotype, suppressible by Ctps^GD4740, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Willoughby et al., 2013)

Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, scrib¹ has neoplasia phenotype, suppressible by Glts^GD14285, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Willoughby et al., 2013)

Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, scrib¹ has neoplasia phenotype, suppressible by bur^GD13797, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Willoughby et al., 2013)

Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, scrib¹ has neoplasia phenotype, suppressible by r^GD9607, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Willoughby et al., 2013)

Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, scrib¹ has neoplasia phenotype, suppressible by Pfas^GD1356, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Willoughby et al., 2013)

Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, scrib¹ has neoplasia phenotype, suppressible by Gfat1^GD7732, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Willoughby et al., 2013)

Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, scrib¹ has neoplasia phenotype, suppressible by Prat^GD9838, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Willoughby et al., 2013)

Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, scrib¹ has neoplasia phenotype, suppressible by Prat2^GD16167, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Willoughby et al., 2013)

Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, scrib¹ has neoplasia phenotype, suppressible by Nadsyn^GD14730, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Willoughby et al., 2013)

Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, nab^EP-nd642 has increased cell growth rate | somatic clone | cell non-autonomous phenotype, suppressible by puc^UAS.cMa

(Suissa et al., 2011)

Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} has neoplasia | somatic clone phenotype, suppressible by Pi3K92E^GD11228, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Willecke et al., 2011)

Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, dlg1^GD4689 has neoplasia | somatic clone phenotype, suppressible by Pi3K92E^GD11228, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Willecke et al., 2011)

Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, Scer\GAL80^ts.αTub84B, dlg1^GD4689 has neoplasia phenotype, suppressible by Pi3K92E^GD11228, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, Scer\GAL80^ts.αTub84B

(Willecke et al., 2011)

Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, Scer\GAL80^ts.αTub84B, dlg1^GD4689 has neoplasia phenotype, suppressible by Akt^GD1361, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, Scer\GAL80^ts.αTub84B

(Willecke et al., 2011)

Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, dlg1^GD4689 has neoplasia phenotype, suppressible by Pi3K92E^1C1

(Willecke et al., 2011)

Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, dlg1^GD4689 has neoplasia phenotype, suppressible by InR^GD104, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Willecke et al., 2011)

Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, dlg1^GD4689 has neoplasia phenotype, suppressible by S6k^GD6646, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Willecke et al., 2011)

Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, dlg1^GD4689 has neoplasia phenotype, suppressible by Rheb^NIG.1081R, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Willecke et al., 2011)

Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, dlg1^GD4689 has neoplasia phenotype, suppressible by mTor^NIG.5092R, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Willecke et al., 2011)

Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, dlg1^GD4689 has neoplasia phenotype, suppressible by Pten^KK109278, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Willecke et al., 2011)

NOT suppressed by

Statement

Reference

Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, nab^EP-nd642 has increased cell growth rate | somatic clone | cell non-autonomous phenotype, non-suppressible by Df(3L)H99

(Suissa et al., 2011)

Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, nab^EP-nd642 has increased cell growth rate | somatic clone | cell non-autonomous phenotype, non-suppressible by Dronc^NIG.8091R, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Suissa et al., 2011)

Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, nab^EP-nd642 has increased cell growth rate | somatic clone | cell non-autonomous phenotype, non-suppressible by Diap1^EP.M, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Suissa et al., 2011)

Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, nab^EP-nd642 has increased cell death | somatic clone | cell non-autonomous phenotype, non-suppressible by p53^D259H.UAS/Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Suissa et al., 2011)

Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, nab^EP-nd642 has increased cell growth rate | somatic clone | cell non-autonomous phenotype, non-suppressible by Df(3L)H99/p53^D259H.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Suissa et al., 2011)

Enhancer of

Statement

Reference

klar^{KASH.UAS.Tag:HA}/Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is an enhancer of increased cell death | oogenesis | somatic clone phenotype of kud^KO

(Ding et al., 2017)

klar^{5'ΔA.UAS.6.Tag:MYC}/Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is an enhancer of increased cell death | oogenesis | somatic clone phenotype of kud^KO

(Ding et al., 2017)

Cbl^L.UAS/Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is an enhancer of increased cell death phenotype of Rbf^120a

(Truscott et al., 2014)

Scer\GAL4^{FRT.Rnor\Cd2.Act5C}/Cbl^S.UAS is an enhancer of increased cell death phenotype of Rbf^120a

(Truscott et al., 2014)

BacA\p35^UAS.cHa, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is an enhancer of increased cell growth rate | cell non-autonomous | somatic clone phenotype of Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, nab^EP-nd642

(Suissa et al., 2011)

dlg1^GD4689, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is an enhancer of neoplasia | somatic clone phenotype of Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Willecke et al., 2011)

yki^UAS.cHa, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is an enhancer of neoplasia | somatic clone phenotype of Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Willecke et al., 2011)

upd1^UAS.cZa, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is an enhancer of neoplasia | somatic clone phenotype of Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Willecke et al., 2011)

yki^UAS.cHa, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is an enhancer of neoplasia phenotype of Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, dlg1^GD4689

(Willecke et al., 2011)

Suppressor of

Statement

Reference

ase^UAS.cBa/Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a suppressor of abnormal neuroanatomy | somatic clone | third instar larval stage phenotype of Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, ato^UAS.cJa

(Mora et al., 2018)

ase^UAS.cBa/Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a suppressor of abnormal cell polarity | somatic clone | third instar larval stage phenotype of Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, ato^UAS.cJa

(Mora et al., 2018)

klar^{3'ΔS.UAS.6.Tag:MYC}/Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a suppressor | partially of increased cell death | somatic clone | oogenesis phenotype of kud^KO

(Ding et al., 2017)

Hsap\TMEM258^UAS.CFP/Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a suppressor of increased cell death | somatic clone | oogenesis phenotype of kud^KO

(Ding et al., 2017)

mir-998^UAS.cTa, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a suppressor | partially of increased cell death phenotype of Cbl^L.UAS, Rbf^120a, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Truscott et al., 2014)

mir-998^UAS.cTa, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a suppressor | partially of increased cell death phenotype of Cbl^S.UAS, Rbf^120a, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Truscott et al., 2014)

mir-11^UAS.DsRed2/Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a suppressor of increased cell death phenotype of E2f1^UAS.cNa

(Truscott et al., 2014)

mir-998^UAS.cTa/Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a suppressor of increased cell death phenotype of Rbf^120a

(Truscott et al., 2014)

Ctps^GD4740, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a suppressor of neoplasia phenotype of Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, scrib¹

(Willoughby et al., 2013)

Glts^GD14285, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a suppressor of neoplasia phenotype of Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, scrib¹

(Willoughby et al., 2013)

bur^GD13797, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a suppressor of neoplasia phenotype of Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, scrib¹

(Willoughby et al., 2013)

r^GD9607, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a suppressor of neoplasia phenotype of Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, scrib¹

(Willoughby et al., 2013)

Pfas^GD1356, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a suppressor of neoplasia phenotype of Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, scrib¹

(Willoughby et al., 2013)

Gfat1^GD7732, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a suppressor of neoplasia phenotype of Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, scrib¹

(Willoughby et al., 2013)

Prat^GD9838, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a suppressor of neoplasia phenotype of Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, scrib¹

(Willoughby et al., 2013)

Prat2^GD16167, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a suppressor of neoplasia phenotype of Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, scrib¹

(Willoughby et al., 2013)

Nadsyn^GD14730, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a suppressor of neoplasia phenotype of Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, scrib¹

(Willoughby et al., 2013)

Pi3K92E^GD11228, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a suppressor of neoplasia | somatic clone phenotype of Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Willecke et al., 2011)

Pi3K92E^GD11228, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a suppressor of neoplasia | somatic clone phenotype of Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, dlg1^GD4689

(Willecke et al., 2011)

Pi3K92E^GD11228, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, Scer\GAL80^ts.αTub84B is a suppressor of neoplasia phenotype of Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, Scer\GAL80^ts.αTub84B, dlg1^GD4689

(Willecke et al., 2011)

Akt^GD1361, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, Scer\GAL80^ts.αTub84B is a suppressor of neoplasia phenotype of Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, Scer\GAL80^ts.αTub84B, dlg1^GD4689

(Willecke et al., 2011)

InR^GD104, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a suppressor of neoplasia phenotype of Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, dlg1^GD4689

(Willecke et al., 2011)

S6k^GD6646, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a suppressor of neoplasia phenotype of Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, dlg1^GD4689

(Willecke et al., 2011)

Rheb^NIG.1081R, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a suppressor of neoplasia phenotype of Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, dlg1^GD4689

(Willecke et al., 2011)

mTor^NIG.5092R, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a suppressor of neoplasia phenotype of Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, dlg1^GD4689

(Willecke et al., 2011)

Pten^KK109278, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a suppressor of neoplasia phenotype of Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, dlg1^GD4689

(Willecke et al., 2011)

NOT Suppressor of

Statement

Reference

mir-998^UAS.cTa/Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a non-suppressor of increased cell death phenotype of E2f1^UAS.cNa

(Truscott et al., 2014)

mir-11^UAS.DsRed2/Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a non-suppressor of increased cell death phenotype of Rbf^120a

(Truscott et al., 2014)

Dronc^NIG.8091R, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a non-suppressor of increased cell growth rate | somatic clone | cell non-autonomous phenotype of Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, nab^EP-nd642

(Suissa et al., 2011)

Diap1^EP.M, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a non-suppressor of increased cell growth rate | somatic clone | cell non-autonomous phenotype of Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, nab^EP-nd642

(Suissa et al., 2011)

p53^D259H.UAS/Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a non-suppressor of increased cell death | somatic clone | cell non-autonomous phenotype of Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, nab^EP-nd642

(Suissa et al., 2011)

Df(3L)H99/p53^D259H.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a non-suppressor of increased cell growth rate | somatic clone | cell non-autonomous phenotype of Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, nab^EP-nd642

(Suissa et al., 2011)

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, da^Δex1.UAS has eye disc anterior to the morphogenetic furrow | somatic clone phenotype, enhanceable by Scer\GAL4^{FRT.Rnor\Cd2.Act5C}/ato^UAS.cJa

(Bhattacharya and Baker, 2011)

Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, da^Δex1.UAS has eye disc morphogenetic furrow | somatic clone phenotype, enhanceable by Scer\GAL4^{FRT.Rnor\Cd2.Act5C}/ato^UAS.cJa

(Bhattacharya and Baker, 2011)

Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, da^Δex1.UAS has eye disc | somatic clone phenotype, enhanceable by Scer\GAL4^{FRT.Rnor\Cd2.Act5C}/ato^UAS.cJa

(Bhattacharya and Baker, 2011)

Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, nab^EP-nd642 has wing disc | cell non-autonomous | somatic clone phenotype, enhanceable by BacA\p35^UAS.cHa, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Suissa et al., 2011)

Suppressed by

Statement

Reference

Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, ato^UAS.cJa has inner optic anlage neuroblast | somatic clone | third instar larval stage phenotype, suppressible by ase^UAS.cBa/Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Mora et al., 2018)

Aduk^UAS.cBa, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} has autophagosome | somatic clone | larval stage phenotype, suppressible by Atg13^Δ81

(Braden and Neufeld, 2016)

Aduk^UAS.cBa, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} has embryonic/larval fat body | somatic clone | larval stage phenotype, suppressible by Atg13^Δ81

(Braden and Neufeld, 2016)

Aduk^UAS.cBa, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} has autophagosome | somatic clone | larval stage phenotype, suppressible by Atg1^K38Q.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Braden and Neufeld, 2016)

Aduk^UAS.cBa, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} has embryonic/larval fat body | somatic clone | larval stage phenotype, suppressible by Atg1^K38Q.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Braden and Neufeld, 2016)

Cbl^L.UAS, Rbf^120a, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} has eye disc phenotype, suppressible | partially by mir-998^UAS.cTa, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Truscott et al., 2014)

Cbl^S.UAS, Rbf^120a, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} has eye disc phenotype, suppressible | partially by mir-998^UAS.cTa, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Truscott et al., 2014)

Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, nab^EP-nd642 has wing disc | somatic clone | cell non-autonomous phenotype, suppressible by puc^UAS.cMa/Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Suissa et al., 2011)

Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, Scer\GAL80^ts.αTub84B, dlg1^GD4689 has eye phenotype, suppressible by Akt^GD1361, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, Scer\GAL80^ts.αTub84B

(Willecke et al., 2011)

Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, Scer\GAL80^ts.αTub84B, dlg1^GD4689 has eye phenotype, suppressible by Pi3K92E^GD11228, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, Scer\GAL80^ts.αTub84B

(Willecke et al., 2011)

NOT suppressed by

Statement

Reference

Aduk^UAS.cBa, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} has embryonic/larval fat body | somatic clone | larval stage phenotype, non-suppressible by Atg1^Δ3D

(Braden and Neufeld, 2016)

Aduk^UAS.cBa, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} has autophagosome | somatic clone | larval stage phenotype, non-suppressible by Atg1^Δ3D

(Braden and Neufeld, 2016)

Enhancer of

Statement

Reference

Cbl^L.UAS/Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is an enhancer of eye disc phenotype of Rbf^120a

(Truscott et al., 2014)

Scer\GAL4^{FRT.Rnor\Cd2.Act5C}/Cbl^S.UAS is an enhancer of eye disc phenotype of Rbf^120a

(Truscott et al., 2014)

Scer\GAL4^{FRT.Rnor\Cd2.Act5C}/ato^UAS.cJa is an enhancer of eye disc anterior to the morphogenetic furrow | somatic clone phenotype of Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, da^Δex1.UAS

(Bhattacharya and Baker, 2011)

Scer\GAL4^{FRT.Rnor\Cd2.Act5C}/ato^UAS.cJa is an enhancer of eye disc morphogenetic furrow | somatic clone phenotype of Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, da^Δex1.UAS

(Bhattacharya and Baker, 2011)

Scer\GAL4^{FRT.Rnor\Cd2.Act5C}/ato^UAS.cJa is an enhancer of eye disc | somatic clone phenotype of Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, da^Δex1.UAS

(Bhattacharya and Baker, 2011)

BacA\p35^UAS.cHa, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is an enhancer of wing disc | cell non-autonomous | somatic clone phenotype of Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, nab^EP-nd642

(Suissa et al., 2011)

Suppressor of

Statement

Reference

ase^UAS.cBa/Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a suppressor of inner optic anlage neuroblast | somatic clone | third instar larval stage phenotype of Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, ato^UAS.cJa

(Mora et al., 2018)

klar^{3'ΔS.UAS.6.Tag:MYC}/Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a suppressor | partially of follicle cell | somatic clone | oogenesis phenotype of kud^KO

(Ding et al., 2017)

klar^{KASH.UAS.Tag:HA}/Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a suppressor | partially of follicle cell | somatic clone | oogenesis phenotype of kud^KO

(Ding et al., 2017)

klar^{5'ΔA.UAS.6.Tag:MYC}/Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a suppressor | partially of follicle cell | somatic clone | oogenesis phenotype of kud^KO

(Ding et al., 2017)

Hsap\TMEM258^UAS.CFP/Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a suppressor of follicle cell | somatic clone | oogenesis phenotype of kud^KO

(Ding et al., 2017)

Atg1^K38Q.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a suppressor of autophagosome | somatic clone | larval stage phenotype of Aduk^UAS.cBa, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Braden and Neufeld, 2016)

Atg1^K38Q.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a suppressor of embryonic/larval fat body | somatic clone | larval stage phenotype of Aduk^UAS.cBa, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Braden and Neufeld, 2016)

mir-998^UAS.cTa, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a suppressor | partially of eye disc phenotype of Cbl^L.UAS, Rbf^120a, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Truscott et al., 2014)

mir-998^UAS.cTa, Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a suppressor | partially of eye disc phenotype of Cbl^S.UAS, Rbf^120a, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

(Truscott et al., 2014)

mir-11^UAS.DsRed2/Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a suppressor of wing phenotype of E2f1^UAS.cNa

(Truscott et al., 2014)

mir-998^UAS.cTa/Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a suppressor of eye disc phenotype of Rbf^120a

(Truscott et al., 2014)

puc^UAS.cMa/Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a suppressor of wing disc | somatic clone | cell non-autonomous phenotype of Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, nab^EP-nd642

(Suissa et al., 2011)

Akt^GD1361, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, Scer\GAL80^ts.αTub84B is a suppressor of eye phenotype of Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, Scer\GAL80^ts.αTub84B, dlg1^GD4689

(Willecke et al., 2011)

Pi3K92E^GD11228, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, Scer\GAL80^ts.αTub84B is a suppressor of eye phenotype of Ras85D^V12.UAS, Scer\GAL4^{FRT.Rnor\Cd2.Act5C}, Scer\GAL80^ts.αTub84B, dlg1^GD4689

(Willecke et al., 2011)

NOT Suppressor of

Statement

Reference

mir-998^UAS.cTa/Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a non-suppressor of wing phenotype of E2f1^UAS.cNa

(Truscott et al., 2014)

mir-11^UAS.DsRed2/Scer\GAL4^{FRT.Rnor\Cd2.Act5C} is a non-suppressor of eye disc phenotype of Rbf^120a

(Truscott et al., 2014)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Fails to rescue

Scer\GAL4^{FRT.Rnor\Cd2.Act5C}/kud^IM-J.UAS.GFP fails to rescue kud^KO

(Ding et al., 2017)

Scer\GAL4^{FRT.Rnor\Cd2.Act5C}/kud^TM-J.UAS.GFP fails to rescue kud^KO

(Ding et al., 2017)

kud^TM-U.UAS.CFP/Scer\GAL4^{FRT.Rnor\Cd2.Act5C} fails to rescue kud^KO

(Ding et al., 2017)

Comments

Images (0)

Mutant

Wild-type

Stocks (9)

Bloomington

4779

y¹ w^* P{GAL4-Act5C(FRT.CD2).P}D

4780

y¹ w^*; P{GAL4-Act5C(FRT.CD2).P}S

39760

P{GAL4-Act5C(FRT.CD2).P}D, y¹ w^*; P{UAS-GFP.U}2

30558

w¹¹¹⁸; P{GAL4-Act5C(FRT.CD2).P}S, P{UAS-RFP.W}3/TM3, Sb¹

64095

y¹ w^* P{ey-FLP.N}2 P{GAL4-Act5C(FRT.CD2).P}D; M{UAS-NowGFP-NLS}ZH-86Fb

76361

P{hsFLP}12, y¹ w^*; P{UAS-GFP-Col4a1}2/SM6a; P{GAL4-Act5C(FRT.CD2).P}S, P{UAS-His-RFP}3/TM6B, Tb¹

51308

w^*; P{Act5C(FRT.polyA)lacZ.nls1}2, P{Ubi-p63E(FRT.STOP)Stinger}9F6/CyO; P{GAL4-Act5C(FRT.CD2).P}S, P{UAS-His-RFP}3/TM3, Sb¹

Kyoto

107874

y¹ w^* P{GAL4-Act5C(FRT.CD2).P}D

107875

y¹ w^*; P{GAL4-Act5C(FRT.CD2).P}S

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

GAL4^{FRT.CD2.Act5C}

Scer\GAL4^{FRT.Rnor\Cd2.Act5C}

Scer\GAL4^{Scer\FRT.Rnor\CD2.Act5C}

Scer\GAL4^{Scer\FRT.Rnor\Cd2.Act5C}

Name Synonyms

Secondary FlyBase IDs

References (397)

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