FlyBase Allele Report: Dmel\Vps11[KK102566]

General Information

Symbol

Dmel\Vps11^KK102566

Species

D. melanogaster

Name

FlyBase ID

FBal0231866

Feature type

allele

Associated gene

Dmel\Vps11

Associated Insertion(s)

Carried in Construct

P{KK102566}

Also Known As

KK102566

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK102566}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK102566

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

fertile, with Scer\GAL4^Tub.PU

(Syrzycka et al., 2019)

increased cell size, with Scer\GAL4^pros.PU

(Lőrincz et al., 2019)

viable, with Scer\GAL4^Tub.PU

(Syrzycka et al., 2019)

Phenotype Manifest In

Detailed Description

Statement

Reference

Garland cells expressing Vps11^KK102566 under the control of Scer\GAL4^pros.PU are enlarged and show enlarged late endosomes (Rab7-positive puncta), but not early endosomes (Rab5-positive puncta).

(Lőrincz et al., 2019)

Expression of Vps11^KK102566 under the control of Scer\GAL4^unspecified results in larvae that exhibit enlargement of late endosomes in garland nephrocytes, as compared to controls.

(Lőrincz et al., 2016)

Fat body clones expressing CG32350^KK102566 under the control of Scer\GAL4^{Scer\FRT.Rnor\CD2.Act5C} exhibit impaired starvation-induced autophagy.

(Takáts et al., 2014)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v107420

P{KK102566}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

CG32350^KK102566

Vps11^KK102566

Vps11[KK102566]

(Takáts et al., 2014)

vps11^RNAi

(Lőrincz et al., 2019)

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

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