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General Information
Symbol
Dmel\AdukUAS.cBa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Braden
FlyBase ID
FBal0326150
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of the Aduk GM08204 cDNA clone.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of AdukScer\UAS.cBa under the control of Scer\GAL4Scer\FRT.Rnor\CD2.Act5C in fat body clones results in an increase in the number of autophagic vesicles (as detected by Atg8a) in well-fed larvae but does not perturb the appearance of autophageosomes in starved larvae relative to the neighboring cells. Scer\GAL4GMR.PU-driven expression leads to reduced adult eye size.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
NOT Enhanced by
Statement
Reference
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Clonal expression of AdukScer\UAS.cBa under the control of Scer\GAL4Scer\FRT.Rnor\CD2.Act5C in the fat body of Atg1Δ3D mutants leads to robust formation of Atg8a-positive (or LysoTracker positive) autophagosome vesicles in both fed and starved conditions, whereas no autophagy induction is observed in Atg13Δ81 mutant clones or clones co-expressing Atg1K38Q.Scer\UAS.

The reduced eye size observed in adult flies expressing AdukScer\UAS.cBa under the control of Scer\GAL4GMR.PU is not further decreased by co-expression of Atg1GS10797 (although Atg1GS10797 expression on its own also leads to small eye phenotype).

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
AdukScer\UAS.cBa
AdukUAS.cBa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Braden
Secondary FlyBase IDs
    References (1)