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General Information
Symbol
Dmel\mir-11UAS.DsRed2
Species
D. melanogaster
Name
FlyBase ID
FBal0178871
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-miR-11
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS sequences drive expression of DsRed2 followed by a genomic fragment that includes mir-11.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Expression of mir-11Scer\UAS.T:Disc\RFP-DsRed2 suppresses the apoptosis seen in the wings of newly eclosed flies expressing E2f1Scer\UAS.cNa under the control of Scer\GAL4Act88F.PD.

Generation of eye disc clones expressing mir-11Scer\UAS.T:Disc\RFP-DsRed2 does not suppress the cell death seen in Rbf120a mutant eye discs.

Expression of mir-11Scer\UAS.T:Disc\RFP-DsRed2 suppresses the apoptosis seen in the eye disc in flies expressing E2f1Scer\UAS.cNa and DpScer\UAS.cDa under the control of Scer\GAL4GMR.PU.

The addition of mir-11Scer\UAS.T:Disc\RFP-DsRed2 does not prevent the ectopic S phases which are induced posterior to the morphogenetic furrow by co-expression of E2fScer\UAS.cNa and DpScer\UAS.cDa under the control of Scer\GAL4GMR.PF. However, co-expression of mir-11Scer\UAS.T:Disc\RFP-DsRed2 does suppress the ability of co-expression of E2fScer\UAS.cNa and DpScer\UAS.cDa under the control of Scer\GAL4GMR.PF to induce apoptosis in the eye disc.

Co-expression of mir-11Scer\UAS.T:Disc\RFP-DsRed2 strongly suppresses the wing defects caused by expression of E2fScer\UAS.cNa under the control of Scer\GAL4Act88F.PD.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
mir-11Scer\UAS.T:Disc\RFP-DsRed2
mir-11Scer\UAS.cBa
mir-11UAS.DsRed2
Name Synonyms
Secondary FlyBase IDs
    References (7)