FB2026_02 , released June 18, 2026
Allele: Dmel\Diap1EP.M
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General Information
Symbol
Dmel\Diap1EP.M
Species
D. melanogaster
Name
FlyBase ID
FBal0143164
Feature type
allele
Associated gene
Dmel\Diap1
Associated Insertion(s)
P{EP(loxP.UAS)y+.UAS}Diap1EP.M
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Moreno et al., 2002)
Progenitor genotype
Associated Insertion(s)
P{EP(loxP.UAS)y+.UAS}Diap1EP.M
Cytology
Description

P{EP(loxP.UAS)y+.UAS} insertion upstream of Diap1.

(Moreno et al., 2002)
Allele components
Component
Use(s)
Inserted element
P{EP(loxP.UAS)y+.UAS}
Regulatory region(s)
UAS
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Diap1EP.M, Scer\GAL4GMR.PF is a suppressor of eye phenotype of Scer\GAL4GMR.PF, egrUAS.cMa

      (Moreno et al., 2002)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of thEP.M and nabEP642 in the wing imaginal disc under the control of Scer\GAL4ap.nd432 abolishes effector caspase activation and apoptosis.

      Co-expression of thEP.M in clones of cells expressing nabEP642 in the wing imaginal disc (under the control of Scer\GAL4Scer\FRT.Rnor\CD2.Act5C) fails to suppress nabEP642-induced tissue overgrowth.

      (Suissa et al., 2011)

      The presence of thEP.M partially supresses the eye ablation phenotype seen in egrScer\UAS.cMa; Scer\GAL4GMR.PF flies.

      (Moreno et al., 2002)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Diap1EP.M
      thEP.M
      Name Synonyms
      Secondary FlyBase IDs
        References (2)