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General Information
Symbol
Dmel\Cad99CΔcyt.UAS.EGFP
Species
D. melanogaster
Name
FlyBase ID
FBal0212158
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
Cad99CΔcyt::GFP
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of a mutated form of Cad99C in which the EGFP tag replaces 256 of the 287 amino acids of the Cad99C cytoplasmic domain.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Overexpression of Cad99CΔcyt.Scer\UAS.T:Avic\GFP-EGFP in the salivary gland under the control of Scer\GAL4fkh.PH results in apical salivary gland membrane expansion. These mutants exhibit an increase in microvilli-like structures and causes apical membranes to protrude into the lateral domain.

Expression of Cad99C&cyt.Scer\UAS.T.Avic\GFP-EGFP in follicle cells under the control of Scer\GAL4Scer\FRT.Rnor\CD2.Act5C induces abnormally tall microvilli that fan out from the apical surface, along with enlarged vitelline bodies. This phenotype is seen in both wild-type and Cad99C21-5/Cad99C21-6 backgrounds.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Cad99CΔcyt.Scer\UAS.T.Avic\GFP-EGFP
Cad99CΔcyt.Scer\UAS.T:Avic\GFP-EGFP
Cad99CΔcyt.UAS.EGFP
Name Synonyms
Secondary FlyBase IDs
    References (3)