Expression of PRL-1Scer\UAS.cPa partially suppresses the pupal lethality seen when Src64BUY1332 is expressed in the dorsal compartment of the wing disc under the control of Scer\GAL4ap-md544, enabling 45% of the expected adults to eclose. The overgrowth and apoptosis seen in the larval wing discs are also suppressed by PRL-1Scer\UAS.cPa.
Expression of PRL-1Scer\UAS.cPa enhances the lethality seen when Ras85DV12.Scer\UAS is expressed in the dorsal compartment of the wing disc under the control of Scer\GAL4ap-md544. Fewer than 10% of mutants reach the prepupal stage, compared to 90% when Ras85DV12.Scer\UAS is expressed alone. The larvae appear lethargic.