FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\kudUAS.CFP
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General Information
Symbol
Dmel\kudUAS.CFP
Species
D. melanogaster
Name
FlyBase ID
FBal0335709
Feature type
allele
Associated gene
Dmel\kud
Associated Insertion(s)
Carried in Construct
P{UAS-kud.CFP}
Key Links
Transgenic product class
wild_type
(Ding et al., 2017)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Ding et al., 2017)
Mutagen
in vitro construct
(Ding et al., 2017)
Progenitor genotype
Carried in construct
P{UAS-kud.CFP}
Cytology
Description

UASt regulates expression of wild type kud tagged at the C-terminus with CFP.

(Ding et al., 2017)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
kud
Tagged with
CFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The expression of kudScer\UAS.T:Avic\GFP-CFP under the control of Scer\GAL4Mef2.247 results in moderate nuclear shape defects and in insignificant to minor nuclear spacing defects (i.e. nuclear clustering) in third instar larval muscle fibers, as compared to controls.

      (Ding et al., 2017)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The minor/insignificant myonuclear spacing defects in third instar larval muscle fibers induced by the expression of kudScer\UAS.T:Avic\GFP-CFP under the control of Scer\GAL4Mef2.247 are enhanced by heterozygosity for either klarΔ1-18 or koi80, leading to moderate nuclear clustering, as compared to controls.

      (Ding et al., 2017)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      kudUAS.CFP/Scer\GAL4FRT.Rnor\Cd2.Act5C rescues kudKO

      (Ding et al., 2017)
      Comments

      The expression of kudScer\UAS.T:Avic\GFP-CFP under the control of Scer\GAL4Scer\FRT.Rnor\Cd2.Act5C rescues both the increased apoptosis and the decreased transverse cell area observed in kudKO homozygous follicular epithelium clones.

      (Ding et al., 2017)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      kudScer\UAS.T:Avic\GFP-CFP
      kudUAS.CFP
      Name Synonyms
      Secondary FlyBase IDs
        References (1)