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General Information
Symbol
Dmel\aseUAS.cBa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Brand
FlyBase ID
FBal0030517
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-ase
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of ase.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expressing aseUAS.cBa under the control of Scer\GAL4FRT.Rnor\Cd2.Act5C has no effect on the mode of division of type III neuroblasts in FLP-out somatic clones in the optic lobe of third instar larvae.

No extra neuroblasts are seen when aseScer\UAS.cBa is expressed under the control of Scer\GAL4wor.PA or Scer\GAL4elav.PU.

Flies expressing aseScer\UAS.cBa under the control of Scer\GAL4hs.PB display in total an average of 10.9 ectopic bristles.

Ectopic expression of aseScer\UAS.cBa, driven by Scer\GAL4pnr-MD237, stimulates sensory organ precursor development in the wing disc to a greater level than wild type.

Expression of aseScer\UAS.cBa under the control of Scer\GAL4C-765 results in the formation of ectopic sensory organs, including ectopic bristles on the notum and ectopic bristles and sensilla campaniformia on the wing.

Expression of aseScer\UAS.cBa under the control of Scer\GAL471B results in a breakdown of the mitotic domain pattern that is present in the outer proliferation center (OPC) of the developing optic lobe.

Expression of aseScer\UAS.cBa under the control of Scer\GAL4455.2 results in extra macrochaetae.

Penetrance and expressivity of bristle phenotype increased with respect to that of asehs.PB, but the spatial and temporal specificity of the effect is unaltered.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressed by
Suppressor of
Additional Comments
Genetic Interactions
Statement
Reference

Co-expression of aseScer\UAS.cBa largely suppresses the production of ectopic intermediate neural progenitor-like cells seen in the type I neuroblasts of the ventral brain and ventral nerve cord when pntScer\UAS.P1.cZa is expressed under the control of Scer\GAL4insc-Mz1407.

Expression of aseScer\UAS.cBa under the control of Scer\GAL4hs.PB suppresses the mechanosensory bristle defects found in scase-1 mutants. The number of defective bristles in scase-1 flies is reduced from an average of 9.7 to 2.5 bristles per fly.

Co-expression of aseScer\UAS.cBa and nvyScer\UAS.cWa, both under the control of Scer\GAL4pnr-MD237, leads to a phenotype that is an intermediate of the two phenotypes seen when each is expressed separately. Resulting larvae have few sensory organ precursors in the wing disc and adults have some bristles on the thorax.

The phenotype caused by expression of aseScer\UAS.cBa under the control of Scer\GAL4455.2 is strongly suppressed by co-expression of esgScer\UAS.cFa.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
aseScer\UAS.cBa
aseUAS.cBa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Brand
Secondary FlyBase IDs
    References (18)