FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Aldh17
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General Information
Symbol
Dmel\Aldh17
Species
D. melanogaster
Name
FlyBase ID
FBal0212193
Feature type
allele
Associated gene
Dmel\Aldh
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Fry and Saweikis, 2006)
Mutagen
Delta2-3 transposase
(Fry and Saweikis, 2006)
Progenitor genotype
P{SUPor-P}AldhKG02748
(Fry and Saweikis, 2006)
Cytology
Description

Imprecise excision of the P{SUPor-P} element, extending into the first intron.

(Fry and Saweikis, 2006)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Aldh17 flies are impaired in total fitness and pre-adult viability when reared under crowded conditions. Homozygous flies show reduced starvation resistance and hypersensitivity to hyperoxia compared to controls.

      (Chakraborty and Fry, 2011)

      Aldh17/Df(2L)N22-14 adults show dramatically reduced ethanol resistance compared to controls; mutants are killed by 4% ethanol, while controls can survive at much higher concentrations. Aldh17/Aldh17 larvae also show low ethanol resistance as they are also killed by 4% ethanol, which does not affect the survival of wild-type larvae.

      (Fry and Saweikis, 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      17
      (Chakraborty and Fry, 2011)
      Aldh17
      AldhΔ17
      (Chakraborty and Fry, 2016)
      line 17
      (Fry and Saweikis, 2006)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)