UASt regulatory sequences drive expression of the N-terminal portion (amino acids 1 to 287) of Hsap\ATXN3. The Hsap\ATXN3 sequence is tagged at the N-terminal end with Tag:MYC.
Co-expression of Hsap\MJDΔ.Scer\UAS.T:Hsap\MYC suppresses the eye degeneration phenotype caused by Hsap\MJDtr.Q78.Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4GMR.PF.