FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\wda11
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General Information
Symbol
Dmel\wda11
Species
D. melanogaster
Name
FlyBase ID
FBal0213198
Feature type
allele
Associated gene
Dmel\wda
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Guelman et al., 2006)
Progenitor genotype
P{SUPor-P}wdaKG03744
(Guelman et al., 2006)
Caused by aberration
Df(3L)wda11
Cytology
Description

Imprecise excision of the progenitor insertion, resulting in a deletion of nucleotides -392 to +1118 relative to the wda transcription start site (this removes part of both the wda and CG13827 transcription units).

(Guelman et al., 2006)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The majority of wda3 mutant embryos (98%) hatch into larvae. Mutant first-instar larvae do not present abnormalities, or movement behaviour and can develop into second instar larvae. However, second instar larvae do not develop beyond that developmental stage.

      A reduction of over 50% in His3-K9 acetylation is observed in wda3 mutants.

      The majority of wda11 mutant embryos (98%) hatch into larvae. Mutant first-instar larvae do not present abnormalities in their mouth parts or movement behaviour and can develop into second instar larvae. However, second instar larvae do not develop beyond that developmental stage.

      (Guelman et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      wda11 is rescued by wdaUAS.cGa/Scer\GAL4αTub84B.PL

      (Guelman et al., 2006)
      Comments

      Lethality in wda11 is rescued by expression of wdaScer\UAS.cGa under the control of Scer\GAL4αTub84B.PK.

      Lethality in wda3 is rescued by expression of wdaScer\UAS.cGa under the control of Scer\GAL4αTub84B.PL.

      Levels of His3-K9 acetylation in wda3 mutants are restored to approximately 80% of wild-type levels by expression of wdaScer\UAS.cGa under the control of Scer\GAL4αTub84B.PL.

      (Guelman et al., 2006)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      wda11
      (Stegeman et al., 2016, Guelman et al., 2006)
      wda3
      Name Synonyms
      Secondary FlyBase IDs
        References (2)