FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Mkp3M76-M
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General Information
Symbol
Dmel\Mkp3M76-M
Species
D. melanogaster
Name
FlyBase ID
FBal0213203
Feature type
allele
Associated gene
Dmel\Mkp3
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Ruiz-Gomez et al., 2005)
Mutagen
ethyl methanesulfonate
(Ruiz-Gomez et al., 2005)
Progenitor genotype
Cytology
Description

Amino acid replacement: Y316N.

(Ruiz-Gomez et al., 2005)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3L:19,069,202..19,069,202 [-]
Nucleotide change:

T19069202A

Reported nucleotide change:

T?A

Amino acid change:

Y146N | Mkp3-PA; Y316N | Mkp3-PB; Y316N | Mkp3-PC; Y316N | Mkp3-PD

Reported amino acid change:

Y316N

(Ruiz-Gomez et al., 2005)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mkp3M76-M homozygotes and Mkp3M76-M/Mkp3M76-R2b transheterozygotes have ectopic wing vein tissue differentiated in the proximal region between veins L4 and L5 and in other wing territories.

      (Ruiz-Gomez et al., 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Chromosome carries a lethal mutation which is probably separable from the Mkp3 locus.

      (Ruiz-Gomez et al., 2005)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Mkp3M76-M
      (Ruiz-Gomez et al., 2005)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)