FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\βggt-IGD10976
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General Information
Symbol
Dmel\βggt-IGD10976
Species
D. melanogaster
Name
FlyBase ID
FBal0213269
Feature type
allele
Associated gene
Dmel\βggt-I
Associated Insertion(s)
Carried in Construct
P{GD10976}
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Dietzl et al., 2007)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Dietzl et al., 2007)
Mutagen
in vitro construct
(Dietzl et al., 2007)
Progenitor genotype
Carried in construct
P{GD10976}
Cytology
Description

UASt regulatory sequences drive expression of an inverted repeat.

(Dietzl et al., 2007)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
dsRNA-GD10976
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression under the control of Scer\GAL41407 results in abnormally large neuroblasts greater than two times the normal cell diameter being seen in the larval brain.

      Expression under the control of Scer\GAL41407 results in an increase in the average size of neuroblasts in the larval brain compared to controls.

      Expression under the control of Scer\GAL41407 results in shorter neuroblast lineages (less daughter cells per neuroblast) in the larval brain compared to controls.

      Expression under the control of Scer\GAL41407 results in mild defects in the shape of neuroblasts in the larval brain.

      (Neumüller et al., 2011)

      Adults expressing βggt-IGD10976 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.

      (Neely et al., 2010)

      Expression under the control of Scer\GAL4Mef2.PR results in grossly normal adult indirect flight muscles.

      Expression under the control of Scer\GAL4Mef2.PR results in morphologically wild-type myofibrils in the adult indirect flight muscles.

      Expression under the control of Scer\GAL4Mef2.PR results in wild-type sarcomeres in the adult indirect flight muscles.

      (Schnorrer et al., 2010)
      External Data
      Linkouts
      Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 2 )
      Linkouts
      Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development
      Neuroblasts Screen Database (Knoblich Lab) - A database for RNAi phenotypes in larval neural stem cells
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      βggt-IGD10976
      Name Synonyms
      Secondary FlyBase IDs
        References (6)