FB2026_02 , released June 18, 2026
Allele: Dmel\COX5ARNAi.cMa
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General Information
Symbol
Dmel\COX5ARNAi.cMa
Species
D. melanogaster
Name
FlyBase ID
FBal0217455
Feature type
allele
Associated gene
Dmel\COX5A
Associated Insertion(s)
Carried in Construct
P{UAS-COX5A.RNAi.M}
Key Links
Transgenic product class
RNAi_reagent
(Mandal et al., 2005)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Mandal et al., 2005)
Mutagen
in vitro construct
(Mandal et al., 2005)
Progenitor genotype
Carried in construct
P{UAS-COX5A.RNAi.M}
Cytology
Description

Template corresponding to unspecified 500bp of coding sequence of CoVa.

(Mandal et al., 2005)
Allele components
Component
Use(s)
Encoded product / tool
COX5A
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of CoVadsRNA.cMa in the posterior signalling center (PSC) under the control of either Scer\GAL4Antp-10 leads to an increase in the number of circulating lamellocytes.

      (Sinenko et al., 2011)

      Transfection of S2 cells with CoVadsRNA.cMa leads to a gradual reduction in ATP levels and a concomitant decrease in cell proliferation rate.

      (Mandal et al., 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      dsRNA has been synthesised from the template and transfected into S2 cells to study the phenotypic consequences of dsRNA interference (RNAi) of the CoVa gene.

      (Mandal et al., 2005)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      COX5ARNAi.cMa
      COX5AdsRNA.cMa
      CoVadsRNA.cMa
      Name Synonyms
      Secondary FlyBase IDs
        References (3)