FlyBase Allele Report: Dmel\nab[EP13]

General Information

Symbol

Dmel\nab^EP13

Species

D. melanogaster

Name

FlyBase ID

FBal0217955

Feature type

allele

Associated gene

Dmel\nab

Associated Insertion(s)

P{EP}nab^EP13

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Félix et al., 2007)

Progenitor genotype

Associated Insertion(s)

P{EP}nab^EP13

Cytology

Description

Insertion of P{EP} at 86bp upstream of the nab transcription initiation site.

(Félix et al., 2007)

Allele components

Component

Use(s)

Inserted element

P{EP}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3L:4,160,996..4,160,996

(Félix et al., 2007)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

viable

(Félix et al., 2007)

visible, with Scer\GAL4^nub-AC-62

(Félix et al., 2007)

visible, with Scer\GAL4^rn-GAL4-13

(Félix et al., 2007)

Phenotype Manifest In

tarsal segment 2, with Scer\GAL4^Dll-md23

(Félix et al., 2007)

tarsal segment 2, with Scer\GAL4^rn-GAL4-13

(Félix et al., 2007)

tarsal segment 3, with Scer\GAL4^Dll-md23

(Félix et al., 2007)

tarsal segment 3, with Scer\GAL4^rn-GAL4-13

(Félix et al., 2007)

tarsal segment 4, with Scer\GAL4^Dll-md23

(Félix et al., 2007)

tarsal segment 4, with Scer\GAL4^rn-GAL4-13

(Félix et al., 2007)

wing hinge, with Scer\GAL4^Dll-md23

(Félix et al., 2007)

wing hinge, with Scer\GAL4^nub-AC-62

(Félix et al., 2007)

wing hinge, with Scer\GAL4^rn-GAL4-13

(Félix et al., 2007)

Detailed Description

Statement

Reference

In nab^EP13; Scer\GAL4^nub-AC-62 adults, the wing hinge is deleted.

In nab^EP13/Scer\GAL4^rn-GAL4-13 adults, tarsal segments 2-4 are deleted or much reduced, and the wing hinge is deleted. The same phenotype is seen in Scer\GAL4^Dll-md23/+; nab^EP13/+ animals.

(Félix et al., 2007)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^rn-GAL4-13, nab^EP13 has wing hinge phenotype, suppressible | partially by rn^UAS.cSPa

(Félix et al., 2007)

Scer\GAL4^rn-GAL4-13, nab^EP13 has tarsal segment 2 phenotype, suppressible | partially by rn^UAS.cSPa

(Félix et al., 2007)

Scer\GAL4^rn-GAL4-13, nab^EP13 has tarsal segment 3 phenotype, suppressible | partially by rn^UAS.cSPa

(Félix et al., 2007)

Scer\GAL4^rn-GAL4-13, nab^EP13 has tarsal segment 4 phenotype, suppressible | partially by rn^UAS.cSPa

(Félix et al., 2007)

Additional Comments

Genetic Interactions

Statement

Reference

The reduction or loss of tarsal segments 2-4 and deletion of the wing hinge seen in nab^EP13/Scer\GAL4^rn-GAL4-13 adults is largely suppressed by rn^{Scer\UAS.cSPa}.

(Félix et al., 2007)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

EP#13

(Diaz-Benjumea, 2008.8.8)

nab^EP13

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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